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Protein

Probable xyloglucan endotransglucosylase/hydrolase protein 8

Gene

XTH8

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity).By similarity

Catalytic activityi

Breaks a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei115NucleophilePROSITE-ProRule annotation1
Active sitei119Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase, Transferase
Biological processCell wall biogenesis/degradation

Enzyme and pathway databases

BioCyciARA:AT1G11545-MONOMER

Protein family/group databases

CAZyiGH16 Glycoside Hydrolase Family 16

Names & Taxonomyi

Protein namesi
Recommended name:
Probable xyloglucan endotransglucosylase/hydrolase protein 8 (EC:2.4.1.207)
Short name:
At-XTH8
Short name:
XTH-8
Gene namesi
Name:XTH8
Ordered Locus Names:At1g11545
ORF Names:T23J18.21
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G11545
TAIRilocus:2823919 AT1G11545

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Apoplast, Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 31Sequence analysisAdd BLAST31
ChainiPRO_000001180832 – 305Probable xyloglucan endotransglucosylase/hydrolase protein 8Add BLAST274

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi61N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi66N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi123N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi138N-linked (GlcNAc...) asparagineSequence analysis1

Post-translational modificationi

Contains at least one intrachain disulfide bond essential for its enzymatic activity.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ8L9A9
PRIDEiQ8L9A9

Expressioni

Gene expression databases

ExpressionAtlasiQ8L9A9 baseline and differential
GenevisibleiQ8L9A9 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G11545.1

Structurei

3D structure databases

ProteinModelPortaliQ8L9A9
SMRiQ8L9A9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 231GH16PROSITE-ProRule annotationAdd BLAST200

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410INDT Eukaryota
ENOG410YAVH LUCA
HOGENOMiHOG000236368
InParanoidiQ8L9A9
KOiK08235
OMAiDYCKDSE
OrthoDBiEOG09360FG8

Family and domain databases

InterProiView protein in InterPro
IPR008264 Beta_glucanase
IPR013320 ConA-like_dom_sf
IPR000757 GH16
IPR008263 GH16_AS
IPR010713 XET_C
IPR016455 XTH
PfamiView protein in Pfam
PF00722 Glyco_hydro_16, 1 hit
PF06955 XET_C, 1 hit
PIRSFiPIRSF005604 XET, 1 hit
PRINTSiPR00737 GLHYDRLASE16
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS01034 GH16_1, 1 hit
PS51762 GH16_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8L9A9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METERRIITS CSAMTALFLF MTALMASSSI AATPTQSFED NFNIMWSENH
60 70 80 90 100
FTTSDDGEIW NLSLDNDTGC GFQTKHMYRF GWFSMKLKLV GGDSAGVVTA
110 120 130 140 150
YYMCSENGAG PERDEIDFEF LGNRTGQPYI IQTNVYKNGT GNREMRHSLW
160 170 180 190 200
FDPTKDYHTY SILWNNHQLV FFVDRVPIRV YKNSDKVPNN DFFPNQKPMY
210 220 230 240 250
LFSSIWNADD WATRGGLEKT DWKKAPFVSS YKDFAVEGCR WKDPFPACVS
260 270 280 290 300
TTTENWWDQY DAWHLSKTQK MDYAWVQRNL VVYDYCKDSE RFPTLPWECS

ISPWA
Length:305
Mass (Da):35,565
Last modified:May 31, 2011 - v2
Checksum:i7A5FDFDDC655ECF7
GO

Sequence cautioni

The sequence AAF16642 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAM66078 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011661 Genomic DNA Translation: AAF16642.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE28750.1
AK228427 mRNA Translation: BAF00360.1
AY088546 mRNA Translation: AAM66078.1 Different initiation.
PIRiG86248
RefSeqiNP_563892.1, NM_101028.4
UniGeneiAt.47525

Genome annotation databases

EnsemblPlantsiAT1G11545.1; AT1G11545.1; AT1G11545
GeneIDi837698
GrameneiAT1G11545.1; AT1G11545.1; AT1G11545
KEGGiath:AT1G11545

Similar proteinsi

Entry informationi

Entry nameiXTH8_ARATH
AccessioniPrimary (citable) accession number: Q8L9A9
Secondary accession number(s): Q0WR89, Q9LPY1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: May 31, 2011
Last modified: May 23, 2018
This is version 122 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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