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Protein

Serine/threonine-protein phosphatase BSL1

Gene

BSL1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Phosphatase involved in elongation process, probably by acting as a regulator of brassinolide signaling.1 Publication

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mn2+By similarityNote: Binds 2 manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi584 – 5841Manganese 1By similarity
Metal bindingi586 – 5861Manganese 1By similarity
Metal bindingi618 – 6181Manganese 1By similarity
Metal bindingi618 – 6181Manganese 2By similarity
Metal bindingi650 – 6501Manganese 2By similarity
Active sitei651 – 6511Proton donorBy similarity
Metal bindingi703 – 7031Manganese 2By similarity
Metal bindingi782 – 7821Manganese 2By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT4G03080-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase BSL1 (EC:3.1.3.16)
Alternative name(s):
BSU1-like protein 1
Gene namesi
Name:BSL1
Ordered Locus Names:At4g03080
ORF Names:T4I9.4
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G03080.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: UniProtKB-SubCell
  • plasma membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 881881Serine/threonine-protein phosphatase BSL1PRO_0000058905Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei491 – 4911PhosphoserineCombined sources
Modified residuei839 – 8391PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8L7U5.
PRIDEiQ8L7U5.

PTM databases

iPTMnetiQ8L7U5.

Expressioni

Tissue specificityi

Expressed in mature cauline leaves and at the tip of influorescence, including flowers. Expressed at lower level in young tissues relative to older ones.1 Publication

Gene expression databases

GenevisibleiQ8L7U5. AT.

Interactioni

Subunit structurei

Interacts with CDG1 and CDL1.1 Publication

Protein-protein interaction databases

BioGridi13388. 4 interactions.
IntActiQ8L7U5. 1 interaction.
STRINGi3702.AT4G03080.1.

Structurei

3D structure databases

ProteinModelPortaliQ8L7U5.
SMRiQ8L7U5. Positions 12-188, 190-359, 550-832.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati60 – 10950Kelch 1Add
BLAST
Repeati269 – 32052Kelch 2Add
BLAST
Repeati338 – 38548Kelch 3Add
BLAST

Sequence similaritiesi

Belongs to the PPP phosphatase family. BSU subfamily.Curated
Contains 3 Kelch repeats.Curated

Keywords - Domaini

Kelch repeat, Repeat

Phylogenomic databases

eggNOGiKOG0374. Eukaryota.
KOG0379. Eukaryota.
COG0639. LUCA.
HOGENOMiHOG000246464.
InParanoidiQ8L7U5.
KOiK01090.
OMAiTFWDDED.
OrthoDBiEOG093602DI.

Family and domain databases

Gene3Di2.120.10.80. 2 hits.
3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR015915. Kelch-typ_b-propeller.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
IPR012391. Ser/Thr_prot_Pase_BSU1.
[Graphical view]
PANTHERiPTHR11668:SF228. PTHR11668:SF228. 2 hits.
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFiPIRSF036363. PPP_BSU1. 1 hit.
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8L7U5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSKPWLHPA PQYKTLETFW DDEDDAPGPR CAHTLTAVAA TKTHGPRLIL
60 70 80 90 100
FGGATAIEGG SSSVPGIRLA GVTNTVHSYD ILTRKWTRLK PAGEPPSPRA
110 120 130 140 150
AHAAAAVGTM VVFQGGIGPA GHSTDDLYVL DMTNDKFKWH RVVVQGDGPG
160 170 180 190 200
PRYGHVMDLV SQRYLVTVTG NDGKRALSDA WALDTAQKPY VWQRLNPDGD
210 220 230 240 250
RPSARMYASG SARSDGMFLL CGGRDTLGAP LGDAYGLLMH RNGQWEWTLA
260 270 280 290 300
PGVAPSPRYQ HAAVFVGARL HVSGGVLRGG RVIDAEASVA VLDTAAGVWL
310 320 330 340 350
DRNGQVTSAR GSKGQIDQDP SFELMRRCRH GAASVGIRIY VHGGLRGDVL
360 370 380 390 400
LDDFLVAENS TFQSDISSPL LASDRTQQSS TPRFSYAARP PSGSEPSFSM
410 420 430 440 450
SEGLSLDENS LEKLTEASAA EAEVASSVWR AAQLGAGTLD EEPSTSDASS
460 470 480 490 500
PIVESTTDGT ANEGDVRLHP RAVVVAKETV GSLGGMVRQL SLDQFQNESR
510 520 530 540 550
RMVPMNNSDV PQPTKKFTRQ KSPQGLHKKV IAALLRPRNW KPPGNRKFFL
560 570 580 590 600
DSYEVGELCY AAEQIFMHEQ TVLQLKAPIK VFGDLHGQFG DLMRLFDEYG
610 620 630 640 650
FPSTAGDITY IDYLFLGDYV DRGQHSLETI TLLLALKIEY PENVHLIRGN
660 670 680 690 700
HEAADINALF GFRLECIERM GENDGIWAWT RFNQLFNYLP LAALIENKII
710 720 730 740 750
CMHGGIGRSI STVEQIEKIE RPITMDAGSL VLMDLLWSDP TENDSIEGLR
760 770 780 790 800
PNARGPGLVT FGPDRVTEFC KRNKLQLIIR AHECVMDGFE RFAQGQLITL
810 820 830 840 850
FSATNYCGTA NNAGAILVVG RGLVIVPKLI HPLPPPILSP ENSPEHSGDD
860 870 880
AWMQELNIQR PPTPTRGRPQ PDFDRSSLAY I
Length:881
Mass (Da):96,146
Last modified:May 3, 2011 - v2
Checksum:i6EC45417BAEBD6E0
GO

Sequence cautioni

The sequence AAC79097 differs from that shown. Reason: Erroneous gene model prediction. Curated
The sequence CAB77793 differs from that shown. Reason: Erroneous gene model prediction. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti794 – 7941Q → P in AAM83219 (PubMed:10617198).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF069442 Genomic DNA. Translation: AAC79097.1. Sequence problems.
AL161496 Genomic DNA. Translation: CAB77793.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE82268.1.
AY126992 mRNA. Translation: AAM83219.1.
PIRiT01385.
RefSeqiNP_192217.2. NM_116542.4.
UniGeneiAt.26278.
At.48826.

Genome annotation databases

EnsemblPlantsiAT4G03080.1; AT4G03080.1; AT4G03080.
GeneIDi828097.
GrameneiAT4G03080.1; AT4G03080.1; AT4G03080.
KEGGiath:AT4G03080.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF069442 Genomic DNA. Translation: AAC79097.1. Sequence problems.
AL161496 Genomic DNA. Translation: CAB77793.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE82268.1.
AY126992 mRNA. Translation: AAM83219.1.
PIRiT01385.
RefSeqiNP_192217.2. NM_116542.4.
UniGeneiAt.26278.
At.48826.

3D structure databases

ProteinModelPortaliQ8L7U5.
SMRiQ8L7U5. Positions 12-188, 190-359, 550-832.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi13388. 4 interactions.
IntActiQ8L7U5. 1 interaction.
STRINGi3702.AT4G03080.1.

PTM databases

iPTMnetiQ8L7U5.

Proteomic databases

PaxDbiQ8L7U5.
PRIDEiQ8L7U5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G03080.1; AT4G03080.1; AT4G03080.
GeneIDi828097.
GrameneiAT4G03080.1; AT4G03080.1; AT4G03080.
KEGGiath:AT4G03080.

Organism-specific databases

TAIRiAT4G03080.

Phylogenomic databases

eggNOGiKOG0374. Eukaryota.
KOG0379. Eukaryota.
COG0639. LUCA.
HOGENOMiHOG000246464.
InParanoidiQ8L7U5.
KOiK01090.
OMAiTFWDDED.
OrthoDBiEOG093602DI.

Enzyme and pathway databases

BioCyciARA:AT4G03080-MONOMER.

Miscellaneous databases

PROiQ8L7U5.

Gene expression databases

GenevisibleiQ8L7U5. AT.

Family and domain databases

Gene3Di2.120.10.80. 2 hits.
3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR015915. Kelch-typ_b-propeller.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
IPR012391. Ser/Thr_prot_Pase_BSU1.
[Graphical view]
PANTHERiPTHR11668:SF228. PTHR11668:SF228. 2 hits.
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFiPIRSF036363. PPP_BSU1. 1 hit.
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBSL1_ARATH
AccessioniPrimary (citable) accession number: Q8L7U5
Secondary accession number(s): Q9ZTA4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: May 3, 2011
Last modified: September 7, 2016
This is version 111 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.