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Q8L7I4

- P2C17_ARATH

UniProt

Q8L7I4 - P2C17_ARATH

Protein

Probable protein phosphatase 2C 17

Gene

At1g78200

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi69 – 691Manganese 1By similarity
    Metal bindingi69 – 691Manganese 2By similarity
    Metal bindingi70 – 701Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi234 – 2341Manganese 2By similarity
    Metal bindingi273 – 2731Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT1G78200-MONOMER.
    ARA:GQT-1433-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 17 (EC:3.1.3.16)
    Short name:
    AtPP2C17
    Gene namesi
    Ordered Locus Names:At1g78200
    ORF Names:T11I11.14
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 1

    Organism-specific databases

    TAIRiAT1G78200.

    Subcellular locationi

    GO - Cellular componenti

    1. plasma membrane Source: TAIR

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 283283Probable protein phosphatase 2C 17PRO_0000367947Add
    BLAST

    Proteomic databases

    PaxDbiQ8L7I4.
    PRIDEiQ8L7I4.

    Expressioni

    Gene expression databases

    GenevestigatoriQ8L7I4.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8L7I4.
    SMRiQ8L7I4. Positions 33-283.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini31 – 275245PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000233896.
    InParanoidiQ8L7I4.
    OMAiAKAYENT.
    PhylomeDBiQ8L7I4.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8L7I4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPKICCSRSA TQVVVAQKSN SGKGRNGEGG IKYGFSLIKG KSNHSMEDYH    50
    VAKFTNFNGN ELGLFAIFDG HKGDHVAAYL QKHLFSNILK DGEFLVDPRR 100
    AIAKAYENTD QKILADNRTD LESGGSTAVT AILINGKALW IANVGDSRAI 150
    VSSRGKAKQM SVDHDPDDDT ERSMIESKGG FVTNRPGDVP RVNGLLAVSR 200
    VFGDKNLKAY LNSEPEIKDV TIDSHTDFLI LASDGISKVM SNQEAVDVAK 250
    KLKDPKEAAR QVVAEALKRN SKDDISCIVV RFR 283
    Length:283
    Mass (Da):30,854
    Last modified:October 1, 2002 - v1
    Checksum:i576000E070123F3E
    GO

    Sequence cautioni

    The sequence AAG52101.1 differs from that shown. Reason: Erroneous gene model prediction.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti198 – 2003VSR → ISS in AAK82506. (PubMed:14593172)Curated
    Sequence conflicti229 – 2313LIL → IIM in AAK82506. (PubMed:14593172)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC012680 Genomic DNA. Translation: AAG52101.1. Sequence problems.
    CP002684 Genomic DNA. Translation: AEE36080.1.
    CP002684 Genomic DNA. Translation: AEE36081.1.
    AY048244 mRNA. Translation: AAK82506.1.
    AY133563 mRNA. Translation: AAM91393.1.
    AK317294 mRNA. Translation: BAH19970.1.
    PIRiD96811.
    RefSeqiNP_565172.1. NM_106470.2.
    NP_974168.1. NM_202439.2.
    UniGeneiAt.18010.

    Genome annotation databases

    EnsemblPlantsiAT1G78200.1; AT1G78200.1; AT1G78200.
    AT1G78200.2; AT1G78200.2; AT1G78200.
    GeneIDi844156.
    KEGGiath:AT1G78200.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC012680 Genomic DNA. Translation: AAG52101.1 . Sequence problems.
    CP002684 Genomic DNA. Translation: AEE36080.1 .
    CP002684 Genomic DNA. Translation: AEE36081.1 .
    AY048244 mRNA. Translation: AAK82506.1 .
    AY133563 mRNA. Translation: AAM91393.1 .
    AK317294 mRNA. Translation: BAH19970.1 .
    PIRi D96811.
    RefSeqi NP_565172.1. NM_106470.2.
    NP_974168.1. NM_202439.2.
    UniGenei At.18010.

    3D structure databases

    ProteinModelPortali Q8L7I4.
    SMRi Q8L7I4. Positions 33-283.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q8L7I4.
    PRIDEi Q8L7I4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT1G78200.1 ; AT1G78200.1 ; AT1G78200 .
    AT1G78200.2 ; AT1G78200.2 ; AT1G78200 .
    GeneIDi 844156.
    KEGGi ath:AT1G78200.

    Organism-specific databases

    TAIRi AT1G78200.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000233896.
    InParanoidi Q8L7I4.
    OMAi AKAYENT.
    PhylomeDBi Q8L7I4.

    Enzyme and pathway databases

    BioCyci ARA:AT1G78200-MONOMER.
    ARA:GQT-1433-MONOMER.

    Gene expression databases

    Genevestigatori Q8L7I4.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
      Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
      , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
      Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Analysis of multiple occurrences of alternative splicing events in Arabidopsis thaliana using novel sequenced full-length cDNAs."
      Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M., Shinozaki K.
      DNA Res. 16:155-164(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    5. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C17_ARATH
    AccessioniPrimary (citable) accession number: Q8L7I4
    Secondary accession number(s): Q94AE3, Q9C9R2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3