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Q8L7I4

- P2C17_ARATH

UniProt

Q8L7I4 - P2C17_ARATH

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Protein
Probable protein phosphatase 2C 17
Gene
At1g78200, T11I11.14
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 magnesium or manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi69 – 691Manganese 1 By similarity
Metal bindingi69 – 691Manganese 2 By similarity
Metal bindingi70 – 701Manganese 1; via carbonyl oxygen By similarity
Metal bindingi234 – 2341Manganese 2 By similarity
Metal bindingi273 – 2731Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT1G78200-MONOMER.
ARA:GQT-1433-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 17 (EC:3.1.3.16)
Short name:
AtPP2C17
Gene namesi
Ordered Locus Names:At1g78200
ORF Names:T11I11.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 1

Organism-specific databases

TAIRiAT1G78200.

Subcellular locationi

GO - Cellular componenti

  1. plasma membrane Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 283283Probable protein phosphatase 2C 17
PRO_0000367947Add
BLAST

Proteomic databases

PaxDbiQ8L7I4.
PRIDEiQ8L7I4.

Expressioni

Gene expression databases

GenevestigatoriQ8L7I4.

Structurei

3D structure databases

ProteinModelPortaliQ8L7I4.
SMRiQ8L7I4. Positions 33-283.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini31 – 275245PP2C-like
Add
BLAST

Sequence similaritiesi

Belongs to the PP2C family.
Contains 1 PP2C-like domain.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ8L7I4.
OMAiAKAYENT.
PhylomeDBiQ8L7I4.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8L7I4-1 [UniParc]FASTAAdd to Basket

« Hide

MPKICCSRSA TQVVVAQKSN SGKGRNGEGG IKYGFSLIKG KSNHSMEDYH    50
VAKFTNFNGN ELGLFAIFDG HKGDHVAAYL QKHLFSNILK DGEFLVDPRR 100
AIAKAYENTD QKILADNRTD LESGGSTAVT AILINGKALW IANVGDSRAI 150
VSSRGKAKQM SVDHDPDDDT ERSMIESKGG FVTNRPGDVP RVNGLLAVSR 200
VFGDKNLKAY LNSEPEIKDV TIDSHTDFLI LASDGISKVM SNQEAVDVAK 250
KLKDPKEAAR QVVAEALKRN SKDDISCIVV RFR 283
Length:283
Mass (Da):30,854
Last modified:October 1, 2002 - v1
Checksum:i576000E070123F3E
GO

Sequence cautioni

The sequence AAG52101.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti198 – 2003VSR → ISS in AAK82506. 1 Publication
Sequence conflicti229 – 2313LIL → IIM in AAK82506. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC012680 Genomic DNA. Translation: AAG52101.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE36080.1.
CP002684 Genomic DNA. Translation: AEE36081.1.
AY048244 mRNA. Translation: AAK82506.1.
AY133563 mRNA. Translation: AAM91393.1.
AK317294 mRNA. Translation: BAH19970.1.
PIRiD96811.
RefSeqiNP_565172.1. NM_106470.2.
NP_974168.1. NM_202439.2.
UniGeneiAt.18010.

Genome annotation databases

EnsemblPlantsiAT1G78200.1; AT1G78200.1; AT1G78200.
AT1G78200.2; AT1G78200.2; AT1G78200.
GeneIDi844156.
KEGGiath:AT1G78200.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC012680 Genomic DNA. Translation: AAG52101.1 . Sequence problems.
CP002684 Genomic DNA. Translation: AEE36080.1 .
CP002684 Genomic DNA. Translation: AEE36081.1 .
AY048244 mRNA. Translation: AAK82506.1 .
AY133563 mRNA. Translation: AAM91393.1 .
AK317294 mRNA. Translation: BAH19970.1 .
PIRi D96811.
RefSeqi NP_565172.1. NM_106470.2.
NP_974168.1. NM_202439.2.
UniGenei At.18010.

3D structure databases

ProteinModelPortali Q8L7I4.
SMRi Q8L7I4. Positions 33-283.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi Q8L7I4.
PRIDEi Q8L7I4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT1G78200.1 ; AT1G78200.1 ; AT1G78200 .
AT1G78200.2 ; AT1G78200.2 ; AT1G78200 .
GeneIDi 844156.
KEGGi ath:AT1G78200.

Organism-specific databases

TAIRi AT1G78200.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000233896.
InParanoidi Q8L7I4.
OMAi AKAYENT.
PhylomeDBi Q8L7I4.

Enzyme and pathway databases

BioCyci ARA:AT1G78200-MONOMER.
ARA:GQT-1433-MONOMER.

Gene expression databases

Genevestigatori Q8L7I4.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Analysis of multiple occurrences of alternative splicing events in Arabidopsis thaliana using novel sequenced full-length cDNAs."
    Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M., Shinozaki K.
    DNA Res. 16:155-164(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C17_ARATH
AccessioniPrimary (citable) accession number: Q8L7I4
Secondary accession number(s): Q94AE3, Q9C9R2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 1, 2002
Last modified: June 11, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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