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Q8L7I0

- GUN19_ARATH

UniProt

Q8L7I0 - GUN19_ARATH

Protein

Endoglucanase 19

Gene

At4g11050

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei412 – 4121By similarity
    Active sitei464 – 4641By similarity
    Active sitei473 – 4731By similarity

    GO - Molecular functioni

    1. carbohydrate binding Source: InterPro
    2. cellulase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cell wall biogenesis/degradation, Cellulose degradation, Polysaccharide degradation

    Enzyme and pathway databases

    BioCyciARA:AT4G11050-MONOMER.

    Protein family/group databases

    CAZyiCBM49. Carbohydrate-Binding Module Family 49.
    GH9. Glycoside Hydrolase Family 9.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Endoglucanase 19 (EC:3.2.1.4)
    Alternative name(s):
    Endo-1,4-beta glucanase 19
    Gene namesi
    Ordered Locus Names:At4g11050
    ORF Names:F2P3.1, T22B4.30
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 4

    Organism-specific databases

    TAIRiAT4G11050.

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2323Sequence AnalysisAdd
    BLAST
    Chaini24 – 626603Endoglucanase 19PRO_0000249271Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi560 – 5601N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi622 – 6221N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiQ8L7I0.
    PRIDEiQ8L7I0.

    Expressioni

    Gene expression databases

    GenevestigatoriQ8L7I0.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8L7I0.
    SMRiQ8L7I0. Positions 26-489.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG05134.
    HOGENOMiHOG000021033.
    InParanoidiQ8L7I0.
    OMAiELNTTRP.
    PhylomeDBiQ8L7I0.

    Family and domain databases

    Gene3Di1.50.10.10. 1 hit.
    InterProiIPR008928. 6-hairpin_glycosidase-like.
    IPR012341. 6hp_glycosidase.
    IPR019028. CBM_49.
    IPR001701. Glyco_hydro_9.
    IPR018221. Glyco_hydro_9_AS.
    [Graphical view]
    PfamiPF09478. CBM49. 1 hit.
    PF00759. Glyco_hydro_9. 1 hit.
    [Graphical view]
    SMARTiSM01063. CBM49. 1 hit.
    [Graphical view]
    SUPFAMiSSF48208. SSF48208. 1 hit.
    PROSITEiPS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
    PS00698. GLYCOSYL_HYDROL_F9_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8L7I0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGSRTTISIL VVLLLGLVQL AISGHDYKQA LSKSILFFEA QRSGHLPPNQ    50
    RVSWRSHSGL YDGKSSGVDL VGGYYDAGDN VKFGLPMAFT VTTMCWSIIE 100
    YGGQLESNGE LGHAIDAVKW GTDYFIKAHP EPNVLYGEVG DGKSDHYCWQ 150
    RPEEMTTDRR AYKIDRNNPG SDLAGETAAA MAAASIVFRR SDPSYSAELL 200
    RHAHQLFEFA DKYRGKYDSS ITVAQKYYRS VSGYNDELLW AAAWLYQATN 250
    DKYYLDYLGK NGDSMGGTGW SMTEFGWDVK YAGVQTLVAK VLMQGKGGEH 300
    TAVFERYQQK AEQFMCSLLG KSTKNIKKTP GGLIFRQSWN NMQFVTSASF 350
    LATVYSDYLS YSKRDLLCSQ GNISPSQLLE FSKSQVDYIL GDNPRATSYM 400
    VGYGENYPRQ VHHRGSSIVS FNVDQKFVTC RGGYATWFSR KGSDPNVLTG 450
    ALVGGPDAYD NFADQRDNYE QTEPATYNNA PLLGVLARLI SGSTGFDQLL 500
    PGVSPTPSPV IIKPAPVPQR KPTKPPAASS PSPITISQKM TNSWKNEGKV 550
    YYRYSTILTN RSTKTLKILK ISITKLYGPI WGVTKTGNSF SFPSWMQSLP 600
    SGKSMEFVYI HSASPADVLV SNYSLE 626
    Length:626
    Mass (Da):69,345
    Last modified:October 1, 2002 - v1
    Checksum:i6F7457C97EEF655F
    GO

    Sequence cautioni

    The sequence AAC35539.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence CAB43040.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence CAB81206.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF080120 Genomic DNA. Translation: AAC35539.1. Sequence problems.
    AL049876 Genomic DNA. Translation: CAB43040.1. Sequence problems.
    AL161518 Genomic DNA. Translation: CAB81206.1. Sequence problems.
    CP002687 Genomic DNA. Translation: AEE82966.1.
    AY133685 mRNA. Translation: AAM91619.1.
    PIRiT01929.
    RefSeqiNP_192843.2. NM_117175.2.
    UniGeneiAt.33589.

    Genome annotation databases

    EnsemblPlantsiAT4G11050.1; AT4G11050.1; AT4G11050.
    GeneIDi826706.
    KEGGiath:AT4G11050.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF080120 Genomic DNA. Translation: AAC35539.1 . Sequence problems.
    AL049876 Genomic DNA. Translation: CAB43040.1 . Sequence problems.
    AL161518 Genomic DNA. Translation: CAB81206.1 . Sequence problems.
    CP002687 Genomic DNA. Translation: AEE82966.1 .
    AY133685 mRNA. Translation: AAM91619.1 .
    PIRi T01929.
    RefSeqi NP_192843.2. NM_117175.2.
    UniGenei At.33589.

    3D structure databases

    ProteinModelPortali Q8L7I0.
    SMRi Q8L7I0. Positions 26-489.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi CBM49. Carbohydrate-Binding Module Family 49.
    GH9. Glycoside Hydrolase Family 9.

    Proteomic databases

    PaxDbi Q8L7I0.
    PRIDEi Q8L7I0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT4G11050.1 ; AT4G11050.1 ; AT4G11050 .
    GeneIDi 826706.
    KEGGi ath:AT4G11050.

    Organism-specific databases

    TAIRi AT4G11050.

    Phylogenomic databases

    eggNOGi NOG05134.
    HOGENOMi HOG000021033.
    InParanoidi Q8L7I0.
    OMAi ELNTTRP.
    PhylomeDBi Q8L7I0.

    Enzyme and pathway databases

    BioCyci ARA:AT4G11050-MONOMER.

    Gene expression databases

    Genevestigatori Q8L7I0.

    Family and domain databases

    Gene3Di 1.50.10.10. 1 hit.
    InterProi IPR008928. 6-hairpin_glycosidase-like.
    IPR012341. 6hp_glycosidase.
    IPR019028. CBM_49.
    IPR001701. Glyco_hydro_9.
    IPR018221. Glyco_hydro_9_AS.
    [Graphical view ]
    Pfami PF09478. CBM49. 1 hit.
    PF00759. Glyco_hydro_9. 1 hit.
    [Graphical view ]
    SMARTi SM01063. CBM49. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48208. SSF48208. 1 hit.
    PROSITEi PS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
    PS00698. GLYCOSYL_HYDROL_F9_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
      Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
      , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
      Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Phylogenetic analysis of the plant endo-beta-1,4-glucanase gene family."
      Libertini E., Li Y., McQueen-Mason S.J.
      J. Mol. Evol. 58:506-515(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY.

    Entry informationi

    Entry nameiGUN19_ARATH
    AccessioniPrimary (citable) accession number: Q8L7I0
    Secondary accession number(s): O82513
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 5, 2006
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3