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Protein

Probable protein S-acyltransferase 19

Gene

PAT19

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Palmitoyl acyltransferase.By similarity1 Publication

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei204S-palmitoyl cysteine intermediateBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BRENDAi2.3.1.225. 399.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein S-acyltransferase 19 (EC:2.3.1.225)
Alternative name(s):
Probable palmitoyltransferase At4g15080
Zinc finger DHHC domain-containing protein At4g15080
Gene namesi
Name:PAT19
Ordered Locus Names:At4g15080
ORF Names:dl3585c, FCAALL.183
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G15080.
TAIRilocus:2129655. AT4G15080.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei16 – 36HelicalSequence analysisAdd BLAST21
Transmembranei41 – 61HelicalSequence analysisAdd BLAST21
Transmembranei222 – 242HelicalSequence analysisAdd BLAST21
Transmembranei277 – 297HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: TAIR

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003636031 – 718Probable protein S-acyltransferase 19Add BLAST718

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiQ8L5Y5.

PTM databases

iPTMnetiQ8L5Y5.
SwissPalmiQ8L5Y5.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G15080.1.

Structurei

3D structure databases

ProteinModelPortaliQ8L5Y5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini174 – 224DHHCPROSITE-ProRule annotationAdd BLAST51

Domaini

The DHHC domain is required for palmitoyltransferase activity.By similarity

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
HOGENOMiHOG000242421.
InParanoidiQ8L5Y5.
KOiK20027.
OMAiVIWDQEA.
OrthoDBiEOG0936048N.
PhylomeDBiQ8L5Y5.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. DHHC. 1 hit.
PROSITEiView protein in PROSITE
PS50216. DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8L5Y5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRKHGWQLP AHKFQVVAIT VFCLLSVAYY AFFAPFVGGR IWEYILLGVY
60 70 80 90 100
SPVALIVFVL YVRCTAINPA DPGIMSKFER GASRGGDLPT AKDISRKFDE
110 120 130 140 150
TGSHLQSSPS VASRTSTLPN SSVKGSVGDA QRVEAAKRKS CFNPLAICCG
160 170 180 190 200
VFVYEDCRSK EETDEQQGDR EEALFCTLCN AEVRKFSKHC RSCDKCVDCF
210 220 230 240 250
DHHCRWLNNC VGRKNYMTFI SLMAVSLLWL LIEAGVGIAV IVRVFVNKKD
260 270 280 290 300
METEIVNRLG NGFSRAPFAT VVGLCTAVSM LALFPLGELF FFHMLLIKKG
310 320 330 340 350
ITTYEYVVAM RAMSEAPAGA SIDEEIPNVL YSPSGSATTG FSGGSSLGLP
360 370 380 390 400
YKGAWCTPPR VFVDYQDEVI PHLDPRMVPS TVDPDAAETA ERGNKIPKRP
410 420 430 440 450
VKISAWKLAK LNSNEATRAA ARARASSSVL RPIENRHLHD DELSSRSGTI
460 470 480 490 500
SVVSSVSTEA NGATLSREIR NNDPMLSHCR NSYAPSQGSR DEYDTGTHSM
510 520 530 540 550
SSLSSPSHVH ETVTLSPLPQ HHTAGHRFTA AAASNSSRPP LNQATNHMIH
560 570 580 590 600
STFDEKIMQK GNHADPLLLP APAASLLRDV RRTSVVWDQE AGRYISVPAT
610 620 630 640 650
TSEPRTRFSS QNQPIPSSHM GNTQNPRPVG HPPQDSSSGR APPPTQQQQG
660 670 680 690 700
ERLMYTGESI FFGGPLVNIP NRDGLRHDGD SGREGQDRMT LTLPREARFK
710
RDTTSNQLPV FAPVGTRK
Length:718
Mass (Da):78,738
Last modified:October 1, 2002 - v1
Checksum:i5ED36F410905780F
GO

Sequence cautioni

The sequence CAB10287 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB78550 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z97337 Genomic DNA. Translation: CAB10287.1. Sequence problems.
AL161540 Genomic DNA. Translation: CAB78550.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE83552.1.
CP002687 Genomic DNA. Translation: ANM66481.1.
AY099860 mRNA. Translation: AAM20711.1.
BT008794 mRNA. Translation: AAP68233.1.
PIRiE71414.
RefSeqiNP_001328372.1. NM_001340991.1.
NP_193244.2. NM_117595.5.
UniGeneiAt.33215.
At.7865.

Genome annotation databases

EnsemblPlantsiAT4G15080.1; AT4G15080.1; AT4G15080.
AT4G15080.2; AT4G15080.2; AT4G15080.
GeneIDi827172.
GrameneiAT4G15080.1; AT4G15080.1; AT4G15080.
AT4G15080.2; AT4G15080.2; AT4G15080.
KEGGiath:AT4G15080.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiZDH17_ARATH
AccessioniPrimary (citable) accession number: Q8L5Y5
Secondary accession number(s): O23362
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: October 1, 2002
Last modified: June 7, 2017
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families