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Protein

Cyclin-dependent kinase B1-1

Gene

CDKB1-1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei33ATPPROSITE-ProRule annotation1
Active sitei136Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 18ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinase B1-1 (EC:2.7.11.22, EC:2.7.11.23)
Short name:
CDKB1;1
Short name:
CDKB;1
Gene namesi
Name:CDKB1-1
Ordered Locus Names:Os01g0897000, LOC_Os01g67160
ORF Names:OsJ_04403, P0674H09.14, P0696G06.32
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002960981 – 303Cyclin-dependent kinase B1-1Add BLAST303

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei14PhosphothreonineBy similarity1
Modified residuei15PhosphotyrosineBy similarity1
Modified residuei170PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8L4P8.

PTM databases

iPTMnetiQ8L4P8.

Expressioni

Tissue specificityi

Expressed in actively dividing cells: root and shoot apical meristems, and young leaves.1 Publication

Inductioni

Down-regulated by sucrose starvation in suspension cell culture.1 Publication

Gene expression databases

GenevisibleiQ8L4P8. OS.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi39947.LOC_Os01g67160.1.

Structurei

3D structure databases

ProteinModelPortaliQ8L4P8.
SMRiQ8L4P8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 295Protein kinasePROSITE-ProRule annotationAdd BLAST292

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0594. Eukaryota.
ENOG410XPP3. LUCA.
HOGENOMiHOG000233024.
InParanoidiQ8L4P8.
KOiK07760.
OMAiDWHVYPQ.
OrthoDBiEOG09360F64.

Family and domain databases

InterProiView protein in InterPro
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
SMARTiView protein in SMART
SM00220. S_TKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8L4P8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKYEKLEKV GEGTYGKVYK AQDRATGQLV ALKKTRLEMD EEGIPPTALR
60 70 80 90 100
EISILRLLSQ SLYVVRLLSV EQATKNGKPV LYLVFEFLDT DLKKFVDAYR
110 120 130 140 150
KGPNPRPLPT NVIKSFLYQL CKGVAHCHGH GVLHRDLKPQ NLLVDKEKGI
160 170 180 190 200
LKIADLGLGR AFTVPMKSYT HEIVTLWYRA PEVLLGSTHY STGVDIWSVG
210 220 230 240 250
CIFAEMVRRQ ALFPGDSELQ QLLHIFRLLG TPTEEQWPGV TDLRDWHEFP
260 270 280 290 300
QWKPQILERQ VPSLEPEGVD LLSKMLQYNP ANRISAKAAM EHPYFDSLDK

SQF
Length:303
Mass (Da):34,602
Last modified:October 1, 2002 - v1
Checksum:i5AAAF71C0C1E281B
GO

Sequence cautioni

The sequence BAD82176 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAF06998 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB239918 mRNA. Translation: BAE93883.1.
AP003316 Genomic DNA. Translation: BAC06275.1.
AP003349 Genomic DNA. Translation: BAD82176.1. Sequence problems.
AP008207 Genomic DNA. Translation: BAF06998.1. Sequence problems.
AP014957 Genomic DNA. Translation: BAS75708.1.
CM000138 Genomic DNA. Translation: EEE55809.1.
RefSeqiXP_015626887.1. XM_015771401.1.
UniGeneiOs.12638.

Genome annotation databases

EnsemblPlantsiOS01T0897000-01; OS01T0897000-01; OS01G0897000.
GeneIDi9269568.
GrameneiOS01T0897000-01; OS01T0897000-01; OS01G0897000.
KEGGiosa:9269568.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiCKB11_ORYSJ
AccessioniPrimary (citable) accession number: Q8L4P8
Secondary accession number(s): A0A0P0VBT7
, B9EVC5, Q0JGY0, Q5N8M3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: October 1, 2002
Last modified: June 7, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families