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Q8L1Z8

- PGK_BARHE

UniProt

Q8L1Z8 - PGK_BARHE

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Bartonella henselae (strain ATCC 49882 / Houston 1) (Rochalimaea henselae)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei36 – 361SubstrateUniRule annotation
    Binding sitei118 – 1181SubstrateUniRule annotation
    Binding sitei151 – 1511SubstrateUniRule annotation
    Binding sitei201 – 2011ATPUniRule annotation
    Binding sitei323 – 3231ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi353 – 3564ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBHEN283166:GIVZ-1502-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:BH15070
    OrganismiBartonella henselae (strain ATCC 49882 / Houston 1) (Rochalimaea henselae)
    Taxonomic identifieri283166 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella
    ProteomesiUP000000421: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 397397Phosphoglycerate kinasePRO_0000145907Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi283166.BH15070.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8L1Z8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni21 – 233Substrate bindingUniRule annotation
    Regioni59 – 624Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227107.
    KOiK00927.
    OMAiAGHPVGK.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8L1Z8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGFRTLDDVD VTGKRVLVRV DFNVPMAQGK VCDDTRLKRH KETLLELQKR    50
    GAKLILLSHC GRPKGQVEPE FSLHPVVQVL EKIINQPVNF ASDCIGVAVQ 100
    TAVEALQNGG ILLLENVRFH SGEEKNAGSF AEALAHNGDL YVNDAFSVSH 150
    RAHASVEGIT HFLPSYAGRS LQCELQALEK GLGKPERPVI AIVGGAKVSS 200
    KLFVLNHLVK KVDYLVIGGG MANSFLAAQG VCVGKSLCEH ALIETVKKVI 250
    EKARECQCTL LLPVDAIVGF RFEKDAPHRL YDIGDIPEDG MILDVGTRSI 300
    AHINAVIDKA ATLVWNGPLG VFEMSPFDQG TIAVARHAAE LSLTGKLVSI 350
    AGGGDTVFAL NHAGVADDFT YLSTAGGAFL EWMEGKMLPG ILALTQA 397
    Length:397
    Mass (Da):42,617
    Last modified:October 1, 2002 - v1
    Checksum:i9CBB50173FE98508
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY074772 Genomic DNA. Translation: AAL74285.1.
    BX897699 Genomic DNA. Translation: CAF28270.1.
    RefSeqiYP_034205.1. NC_005956.1.

    Genome annotation databases

    EnsemblBacteriaiCAF28270; CAF28270; BH15070.
    GeneIDi2865020.
    KEGGibhe:BH15070.
    PATRICi20547250. VBIBarHen29080_1733.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY074772 Genomic DNA. Translation: AAL74285.1 .
    BX897699 Genomic DNA. Translation: CAF28270.1 .
    RefSeqi YP_034205.1. NC_005956.1.

    3D structure databases

    ProteinModelPortali Q8L1Z8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 283166.BH15070.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAF28270 ; CAF28270 ; BH15070 .
    GeneIDi 2865020.
    KEGGi bhe:BH15070.
    PATRICi 20547250. VBIBarHen29080_1733.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227107.
    KOi K00927.
    OMAi AGHPVGK.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci BHEN283166:GIVZ-1502-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 49882 / Houston 1.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 49882 / Houston 1.

    Entry informationi

    Entry nameiPGK_BARHE
    AccessioniPrimary (citable) accession number: Q8L1Z8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2004
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3