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Reviewed, UniProtKB/Swiss-Prot Q8KZM8 (BIOD_BACNA)

Last modified February 9, 2010. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Dethiobiotin synthetase
    EC=6.3.3.3
Alternative name(s):
    Dethiobiotin synthase
    DTB synthetase
      Short name=DTBS
Gene names
Name: bioD
OrganismBacillus subtilis subsp. natto
Taxonomic identifier86029 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesBacillaceaeBacillus

Protein attributes

Sequence length231 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. HAMAP MF_00336

Cofactor

Magnesium By similarity. HAMAP MF_00336

Pathway

Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. HAMAP MF_00336

Sequence similarities

Belongs to the dethiobiotin synthetase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 231231Dethiobiotin synthetase HAMAP MF_00336
PRO_0000187947

Regions

Nucleotide binding8 – 169ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8KZM8-1 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 44146F6456CC9151

FASTA23125,188
        10         20         30         40         50         60 
MRGFFVTGTD TEVGKTVISS GLAALLKEHN RDVGVYKPFL SGISRHHPDS DTSLLKDMSQ 

        70         80         90        100        110        120 
TSLSHEDITP FAFKAPLAPY VAGKLEGKTV TMEEVLSHWG RIREKHECFI VEGAGGISVP 

       130        140        150        160        170        180 
LGEDYLVSHV IKALQLPMII VARPHLGTIN HTFLTVKYAE SMGLPIAGII INGISDSPDE 

       190        200        210        220        230 
DEKTNPEMIE RLCGVPILGV TPKLANVTKE TVLHMVKDHI NLSLLMNQMG V 

« Hide

References

[1]"Genetic analysis of biotin operon in Bacillus subtilis natto OK2."
Sasaki M., Kotanagi T., Kurusu Y.
Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: OK2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB088066 Genomic DNA. Translation: BAC03242.1.

3D structure databases

SMRQ8KZM8. Positions 3-210.
ModBaseSearch...

Enzyme and pathway databases

BRENDA6.3.3.3. 298357.

Family and domain databases

HAMAPMF_00336. BioD.
[Tree]
InterProIPR004472. BioD_synth.
[Graphical view]
PIRSFPIRSF006755. DTB_synth. 1 hit.
TIGRFAMsTIGR00347. bioD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameBIOD_BACNA
AccessionPrimary (citable) accession number: Q8KZM8
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: October 1, 2002
Last modified: February 9, 2010
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents