Q8KUH2 (Q8KUH2_ACTPA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
3-amino-5-hydroxybenzoate synthase EMBL AAM54102.1

Gene names

Name:

asm24 EMBL AAM54102.1

Organism

Actinosynnema pretiosum subsp. auranticum EMBL AAM54102.1

Taxonomic identifier

42198 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Actinosynnemataceae › Actinosynnema

Protein attributes

Sequence length	388 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the degT/dnrJ/eryC1 family. RuleBase RU004508

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU004509
Gene Ontology (GO)
Molecular function	catalytic activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8KUH2 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: E9BEA4F42D14E626	FASTA	388	42,202
	10 20 30 40 50 60 MHLKAPQKLE FPAWPQFDST EREALLRTLD SGRWWRITGD EVVSFEREFA QAHGARHALA 70 80 90 100 110 120 VTTGTHALEL VLEVMGAGPG TEVIVPAFTF ISSSQAAQRL GAVVVPVDVD PDTYCVDPAA 130 140 150 160 170 180 VRAAITERTR AIMPVHMAGQ LADMDALRAL SAETGVPLLQ DAAHAHGARW RGEPLGALGS 190 200 210 220 230 240 IAAFSFQNGK LMTAGEGGAV LLPDGDQHEE AFLRHACGRP LADRAYHHRT AGSNFRMNEF 250 260 270 280 290 300 SAALLRAQLG RLQQQTDVRE RHWPVLSRLL AEVPGVVPQG TDPRCDRNPH YMAMFQVPGI 310 320 330 340 350 360 GEERRARLVD ALVERGVPAF AGFRAIYRTA AFWERAAPDT TVDALARACP VTEALSSDCV 370 380 WLHHRVLLGA EEQMPLVAEA VACALEEA

References

[1]	"The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum." Yu T.W., Bai L., Clade D., Hoffmann D., Toelzer S., Trinh K.Q., Xu J., Moss S.J., Leistner E., Floss H.G. Proc. Natl. Acad. Sci. U.S.A. 99:7968-7973(2002) [PubMed: 12060743] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: ATCC 31565 EMBL AAM54102.1.
[2]	Yu T.-W., Bai L., Clade D., Hoffmann D., Toelzer S., Trinh K.Q., Xu J., Moss S.J., Leistner E., Floss H.G. Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: ATCC 31565 EMBL AAM54102.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF453501 Genomic DNA. Translation: AAM54102.1.
3D structure databases
HSSP	HSSP built from PDB template 1B9H based on UniProtKB O52552.
ProteinModelPortal	Q8KUH2.
SMR	Q8KUH2. Positions 4-388.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR000653. DegT/StrS_aminotransferase. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
Pfam	PF01041. DegT_DnrJ_EryC1. 1 hit. [Graphical view]
PIRSF	PIRSF000390. PLP_StrS. 1 hit.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8KUH2_ACTPA

Accession

Primary (citable) accession number: Q8KUH2

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	March 8, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)