Q8KUF8 (Q8KUF8_ACTPA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Methyltransferase EMBL AAM54088.1

Gene names

Name:

asm10 EMBL AAM54088.1

Organism

Actinosynnema pretiosum subsp. auranticum EMBL AAM54088.1

Taxonomic identifier

42198 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Actinosynnemataceae › Actinosynnema

Protein attributes

Sequence length	294 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function

Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity By similarity. SAAS SAAS007213

Ontologies

Keywords
Ligand	S-adenosyl-L-methionine SAAS SAAS007213
Molecular function	Methyltransferase SAAS SAAS011610 EMBL AAM54088.1 Transferase
Gene Ontology (GO)
Molecular function	methyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8KUF8 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 7AD7E3E5E6625AE6	FASTA	294	30,764
	10 20 30 40 50 60 MSLPADSPPP GPVEMPDESW TSLGNAGARA QESARADRLF DDPLARAFLD AAGTGNPLLP 70 80 90 100 110 120 DRGGGDPGLL GQITDVIVVK TVFFDAVLAR AAAAGVRQVV LLAAGLDARA FRLPWPEGVV 130 140 150 160 170 180 VFEVDLPDVL GFKERVVREV GAEPSCDRRV VAADLRSDWV AALVAAGLDR EAPVAWLAEG 190 200 210 220 230 240 ALGLLDEAGC EELMAAVLGA SAAGSRFALD HTHDGWKAGE ALGGYLEGTG VCLADLVKGG 250 260 270 280 290 PREPGGAWLA RHGWRVAEYD VVAEAARHGR PAPTLFRVPE RRANATILFE AELG

References

[1]	"The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum." Yu T.W., Bai L., Clade D., Hoffmann D., Toelzer S., Trinh K.Q., Xu J., Moss S.J., Leistner E., Floss H.G. Proc. Natl. Acad. Sci. U.S.A. 99:7968-7973(2002) [PubMed: 12060743] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: ATCC 31565 EMBL AAM54088.1.
[2]	Yu T.-W., Bai L., Clade D., Hoffmann D., Toelzer S., Trinh K.Q., Xu J., Moss S.J., Leistner E., Floss H.G. Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: ATCC 31565 EMBL AAM54088.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF453501 Genomic DNA. Translation: AAM54088.1.
3D structure databases
ProteinModelPortal	Q8KUF8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR011610. CHP00027_methylltransferase. IPR007213. LCM_MeTrfase. [Graphical view]
Pfam	PF04072. LCM. 1 hit. [Graphical view]
TIGRFAMs	TIGR00027. Mthyl_TIGR00027. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8KUF8_ACTPA

Accession

Primary (citable) accession number: Q8KUF8

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	September 21, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)