Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Orf14

Gene
N/A
Organism
Streptomyces clavuligerus
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • clavulanic acid biosynthetic process Source: CACAO
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Orf14Imported
OrganismiStreptomyces clavuligerusImported
Taxonomic identifieri1901 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

Interactioni

Protein-protein interaction databases

STRINGi443255.SclaA2_010100020068.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2WPWX-ray2.38A/B/C/D1-339[»]
2WPXX-ray2.31A/B1-339[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini8 – 170163N-acetyltransferaseInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4105ZQS. Bacteria.
ENOG4111JCT. LUCA.

Family and domain databases

Gene3Di3.40.630.30. 2 hits.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
[Graphical view]
PfamiPF00583. Acetyltransf_1. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 2 hits.
PROSITEiPS51186. GNAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8KRB5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNDTAGELEF VPLAANDDET VGQWLDLMAL AAETGPRAAP PCNVDMVGSL
60 70 80 90 100
RFAPPATALD DWVVRSGGRV VGALRLALPD GAPTARVDQL LVHPGRRRRG
110 120 130 140 150
IGRALWAHAR ELARKHDRTT LTATVVESLP SGPAQDPGPA AFAAAMGAHR
160 170 180 190 200
SDIPAGTHQW LDLDRHDPLA DGVPAVPAGY SLVTWGTITP DEYAVPVSEL
210 220 230 240 250
ELSLGAGPVD RAAQEVRTSY ARQFETMRVG RGRRAYHTGA VHDATGALAG
260 270 280 290 300
YTSVSKTTGN PAYALQGMTV VHREHRGHAL GTLLKLANLE YVLRHEPEVR
310 320 330
LVETANAEDN HPMIAVNAAL GFEPYDRWVF WTAEAGPSD
Length:339
Mass (Da):36,293
Last modified:October 1, 2002 - v1
Checksum:iA8EDACA92F5FEEEF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY034175 Genomic DNA. Translation: AAK56492.1.
AY258009 Genomic DNA. Translation: AAP13503.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY034175 Genomic DNA. Translation: AAK56492.1.
AY258009 Genomic DNA. Translation: AAP13503.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2WPWX-ray2.38A/B/C/D1-339[»]
2WPXX-ray2.31A/B1-339[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi443255.SclaA2_010100020068.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4105ZQS. Bacteria.
ENOG4111JCT. LUCA.

Family and domain databases

Gene3Di3.40.630.30. 2 hits.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
[Graphical view]
PfamiPF00583. Acetyltransf_1. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 2 hits.
PROSITEiPS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The clavulanic acid biosynthetic cluster of Streptomyces clavuligerus: genetic organization of the region upstream of the car gene."
    Mellado E., Lorenzana L.M., Rodriguez-Saiz M., Diez B., Liras P., Barredo J.L.
    Microbiology 148:1427-1438(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Five additional genes are involved in clavulanic acid biosynthesis in Streptomyces clavuligerus."
    Jensen S.E., Paradkar A.S., Mosher R.H., Anders C., Beatty P.H., Brumlik M.J., Griffin A., Barton B.
    Antimicrob. Agents Chemother. 48:192-202(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "Crystallographic and mass spectrometric analyses of a tandem GNAT protein from the clavulanic acid biosynthesis pathway."
    Iqbal A., Arunlanantham H., Brown T., Chowdhury R., Clifton I.J., Kershaw N.J., Hewitson K.S., McDonough M.A., Schofield C.J.
    Proteins 78:1398-1407(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.31 ANGSTROMS).

Entry informationi

Entry nameiQ8KRB5_STRCL
AccessioniPrimary (citable) accession number: Q8KRB5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: May 11, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.