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Protein
Submitted name:

WbpP

Gene
N/A
Organism
Pseudomonas aeruginosa
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei98 – 981NAD; via carbonyl oxygenCombined sources
Binding sitei117 – 1171NADCombined sources
Binding sitei166 – 1661NADCombined sources
Binding sitei170 – 1701NADCombined sources
Binding sitei196 – 1961NAD; via amide nitrogenCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi26 – 283NADCombined sources
Nucleotide bindingi47 – 526NADCombined sources
Nucleotide bindingi78 – 792NADCombined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

NADCombined sources, Nucleotide-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
WbpPImported
OrganismiPseudomonas aeruginosaImported
Taxonomic identifieri287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1SB8X-ray2.10A1-341[»]
1SB9X-ray2.50A1-341[»]
ProteinModelPortaliQ8KN66.
SMRiQ8KN66. Positions 1-341.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8KN66.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini19 – 264246EpimeraseInterPro annotationAdd
BLAST

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR001509. Epimerase_deHydtase_N.
IPR016040. NAD(P)-bd_dom.
IPR008089. Nuc_sugar_epim.
[Graphical view]
PfamiPF01370. Epimerase. 1 hit.
[Graphical view]
PRINTSiPR01713. NUCEPIMERASE.
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8KN66-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSRYEELRK ELPAQPKVWL ITGVAGFIGS NLLETLLKLD QKVVGLDNFA
60 70 80 90 100
TGHQRNLDEV RSLVSEKQWS NFKFIQGDIR NLDDCNNACA GVDYVLHQAA
110 120 130 140 150
LGSVPRSIND PITSNATNID GFLNMLIAAR DAKVQSFTYA ASSSTYGDHP
160 170 180 190 200
GLPKVEDTIG KPLSPYAVTK YVNELYADVF SRCYGFSTIG LRYFNVFGRR
210 220 230 240 250
QDPNGAYAAV IPKWTSSMIQ GDDVYINGDG ETSRDFCYIE NTVQANLLAA
260 270 280 290 300
TAGLDARNQV YNIAVGGRTS LNQLFFALRD GLAENGVSYH REPVYRDFRE
310 320 330 340
GDVRHSLADI SKAAKLLGYA PKYDVSAGVA LAMPWYIMFL K
Length:341
Mass (Da):37,749
Last modified:October 1, 2002 - v1
Checksum:i15835AFAB8219061
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF498417 Genomic DNA. Translation: AAM27817.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF498417 Genomic DNA. Translation: AAM27817.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1SB8X-ray2.10A1-341[»]
1SB9X-ray2.50A1-341[»]
ProteinModelPortaliQ8KN66.
SMRiQ8KN66. Positions 1-341.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiQ8KN66.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR001509. Epimerase_deHydtase_N.
IPR016040. NAD(P)-bd_dom.
IPR008089. Nuc_sugar_epim.
[Graphical view]
PfamiPF01370. Epimerase. 1 hit.
[Graphical view]
PRINTSiPR01713. NUCEPIMERASE.
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genetic variation at the O-antigen biosynthetic locus in Pseudomonas aeruginosa."
    Raymond C.K., Sims E.H., Kas A., Spencer D.H., Kutyavin T.V., Ivey R.G., Zhou Y., Kaul R., Clendenning J.B., Olson M.V.
    J. Bacteriol. 184:3614-3622(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Crystal structure of WbpP, a genuine UDP-N-acetylglucosamine 4-epimerase from Pseudomonas aeruginosa: substrate specificity in udp-hexose 4-epimerases."
    Ishiyama N., Creuzenet C., Lam J.S., Berghuis A.M.
    J. Biol. Chem. 279:22635-22642(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) IN COMPLEX WITH NAD.

Entry informationi

Entry nameiQ8KN66_PSEAI
AccessioniPrimary (citable) accession number: Q8KN66
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: March 16, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.