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Q8KKS1

- APT2_RHIEC

UniProt

Q8KKS1 - APT2_RHIEC

Protein

Adenine phosphoribosyltransferase 2

Gene

apt2

Organism
Rhizobium etli (strain CFN 42 / ATCC 51251)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 2 (04 Apr 2006)
      Previous versions | rss
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    Functioni

    Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.UniRule annotation

    Catalytic activityi

    AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. adenine phosphoribosyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. adenine salvage Source: InterPro
    2. AMP salvage Source: UniProtKB-UniPathway
    3. purine ribonucleoside salvage Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Purine salvage

    Enzyme and pathway databases

    BioCyciRETL347834:GJJ0-5567-MONOMER.
    UniPathwayiUPA00588; UER00646.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Adenine phosphoribosyltransferase 2UniRule annotation (EC:2.4.2.7UniRule annotation)
    Short name:
    APRT 2UniRule annotation
    Gene namesi
    Name:apt2UniRule annotation
    Ordered Locus Names:RHE_PD00341
    Encoded oniPlasmid sym p42d0 Publication
    OrganismiRhizobium etli (strain CFN 42 / ATCC 51251)
    Taxonomic identifieri347834 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
    ProteomesiUP000001936: Plasmid sym p42d

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 184184Adenine phosphoribosyltransferase 2PRO_0000334716Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi347834.RHE_PD00341.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8KKS1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the purine/pyrimidine phosphoribosyltransferase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0503.
    HOGENOMiHOG000036776.
    KOiK00759.
    OMAiAPVISAM.
    OrthoDBiEOG6T4S55.

    Family and domain databases

    Gene3Di3.40.50.2020. 1 hit.
    HAMAPiMF_00004. Aden_phosphoribosyltr.
    InterProiIPR005764. Ade_phspho_trans.
    IPR000836. PRibTrfase_dom.
    IPR029057. PRTase-like.
    [Graphical view]
    PfamiPF00156. Pribosyltran. 1 hit.
    [Graphical view]
    SUPFAMiSSF53271. SSF53271. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8KKS1-1 [UniParc]FASTAAdd to Basket

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    MIVAVPNSGA SRINQSGVEA LREFPNFPIG GILFKDIAPM LAGRGALGEV    50
    VSTVASQVSG TEIDAILAVD ARGFILGASL ADRLGCGFIM VRKPGKLPGD 100
    VLSFEYSCEY CSGTLEVTAG LIGDGLRCLI ADDLLATGGT ARATGNFVKS 150
    QGGEIAGYAF ILEIEVLKGR RQLDDAPVIS AMTC 184
    Length:184
    Mass (Da):19,027
    Last modified:April 4, 2006 - v2
    Checksum:i9B715686CDB75F91
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U80928 Genomic DNA. Translation: AAM55053.2.
    RefSeqiNP_660052.2. NC_004041.2.

    Genome annotation databases

    EnsemblBacteriaiAAM55053; AAM55053; RHE_PD00341.
    GeneIDi1005231.
    KEGGiret:RHE_PD00341.
    PATRICi23081243. VBIRhiEtl108884_0314.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U80928 Genomic DNA. Translation: AAM55053.2 .
    RefSeqi NP_660052.2. NC_004041.2.

    3D structure databases

    ProteinModelPortali Q8KKS1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 347834.RHE_PD00341.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM55053 ; AAM55053 ; RHE_PD00341 .
    GeneIDi 1005231.
    KEGGi ret:RHE_PD00341.
    PATRICi 23081243. VBIRhiEtl108884_0314.

    Phylogenomic databases

    eggNOGi COG0503.
    HOGENOMi HOG000036776.
    KOi K00759.
    OMAi APVISAM.
    OrthoDBi EOG6T4S55.

    Enzyme and pathway databases

    UniPathwayi UPA00588 ; UER00646 .
    BioCyci RETL347834:GJJ0-5567-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.2020. 1 hit.
    HAMAPi MF_00004. Aden_phosphoribosyltr.
    InterProi IPR005764. Ade_phspho_trans.
    IPR000836. PRibTrfase_dom.
    IPR029057. PRTase-like.
    [Graphical view ]
    Pfami PF00156. Pribosyltran. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53271. SSF53271. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CFN 42 / ATCC 51251.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CFN 42 / ATCC 51251.

    Entry informationi

    Entry nameiAPT2_RHIEC
    AccessioniPrimary (citable) accession number: Q8KKS1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: April 4, 2006
    Last modified: October 1, 2014
    This is version 74 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Plasmid, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3