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Q8KKS1

- APT2_RHIEC

UniProt

Q8KKS1 - APT2_RHIEC

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Protein

Adenine phosphoribosyltransferase 2

Gene

apt2

Organism
Rhizobium etli (strain CFN 42 / ATCC 51251)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.UniRule annotation

Catalytic activityi

AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. adenine phosphoribosyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. adenine salvage Source: InterPro
  2. AMP salvage Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Purine salvage

Enzyme and pathway databases

BioCyciRETL347834:GJJ0-5567-MONOMER.
UniPathwayiUPA00588; UER00646.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine phosphoribosyltransferase 2UniRule annotation (EC:2.4.2.7UniRule annotation)
Short name:
APRT 2UniRule annotation
Gene namesi
Name:apt2UniRule annotation
Ordered Locus Names:RHE_PD00341
Encoded oniPlasmid sym p42d0 Publication
OrganismiRhizobium etli (strain CFN 42 / ATCC 51251)
Taxonomic identifieri347834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
ProteomesiUP000001936: Plasmid sym p42d

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 184184Adenine phosphoribosyltransferase 2PRO_0000334716Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi347834.RHE_PD00341.

Structurei

3D structure databases

ProteinModelPortaliQ8KKS1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the purine/pyrimidine phosphoribosyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0503.
HOGENOMiHOG000036776.
KOiK00759.
OMAiAPVISAM.
OrthoDBiEOG6T4S55.

Family and domain databases

Gene3Di3.40.50.2020. 1 hit.
HAMAPiMF_00004. Aden_phosphoribosyltr.
InterProiIPR005764. Ade_phspho_trans.
IPR000836. PRibTrfase_dom.
IPR029057. PRTase-like.
[Graphical view]
PfamiPF00156. Pribosyltran. 1 hit.
[Graphical view]
SUPFAMiSSF53271. SSF53271. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8KKS1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIVAVPNSGA SRINQSGVEA LREFPNFPIG GILFKDIAPM LAGRGALGEV
60 70 80 90 100
VSTVASQVSG TEIDAILAVD ARGFILGASL ADRLGCGFIM VRKPGKLPGD
110 120 130 140 150
VLSFEYSCEY CSGTLEVTAG LIGDGLRCLI ADDLLATGGT ARATGNFVKS
160 170 180
QGGEIAGYAF ILEIEVLKGR RQLDDAPVIS AMTC
Length:184
Mass (Da):19,027
Last modified:April 4, 2006 - v2
Checksum:i9B715686CDB75F91
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U80928 Genomic DNA. Translation: AAM55053.2.
RefSeqiNP_660052.2. NC_004041.2.
WP_004672710.1. NC_004041.2.

Genome annotation databases

EnsemblBacteriaiAAM55053; AAM55053; RHE_PD00341.
GeneIDi1005231.
KEGGiret:RHE_PD00341.
PATRICi23081243. VBIRhiEtl108884_0314.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U80928 Genomic DNA. Translation: AAM55053.2 .
RefSeqi NP_660052.2. NC_004041.2.
WP_004672710.1. NC_004041.2.

3D structure databases

ProteinModelPortali Q8KKS1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 347834.RHE_PD00341.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM55053 ; AAM55053 ; RHE_PD00341 .
GeneIDi 1005231.
KEGGi ret:RHE_PD00341.
PATRICi 23081243. VBIRhiEtl108884_0314.

Phylogenomic databases

eggNOGi COG0503.
HOGENOMi HOG000036776.
KOi K00759.
OMAi APVISAM.
OrthoDBi EOG6T4S55.

Enzyme and pathway databases

UniPathwayi UPA00588 ; UER00646 .
BioCyci RETL347834:GJJ0-5567-MONOMER.

Family and domain databases

Gene3Di 3.40.50.2020. 1 hit.
HAMAPi MF_00004. Aden_phosphoribosyltr.
InterProi IPR005764. Ade_phspho_trans.
IPR000836. PRibTrfase_dom.
IPR029057. PRTase-like.
[Graphical view ]
Pfami PF00156. Pribosyltran. 1 hit.
[Graphical view ]
SUPFAMi SSF53271. SSF53271. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CFN 42 / ATCC 51251.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CFN 42 / ATCC 51251.

Entry informationi

Entry nameiAPT2_RHIEC
AccessioniPrimary (citable) accession number: Q8KKS1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 4, 2006
Last modified: October 29, 2014
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3