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Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) (Chlorobium tepidum)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease, RNA-binding
Biological processtRNA processing

Enzyme and pathway databases

BioCyciCTEP194439:G1FZE-4-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
Ordered Locus Names:CT0004
OrganismiChlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) (Chlorobium tepidum)
Taxonomic identifieri194439 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobaculum
Proteomesi
  • UP000001007 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001984471 – 154Ribonuclease P protein componentAdd BLAST154

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

Protein-protein interaction databases

STRINGi194439.CT0004

Structurei

3D structure databases

ProteinModelPortaliQ8KGG4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG41086JU Bacteria
ENOG410ZYVZ LUCA
HOGENOMiHOG000155258
KOiK03536
OMAiKHEILRK
OrthoDBiPOG091H011Y

Family and domain databases

Gene3Di3.30.230.10, 1 hit
HAMAPiMF_00227 RNase_P, 1 hit
InterProiView protein in InterPro
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
IPR000100 RNase_P
IPR020539 RNase_P_CS
PfamiView protein in Pfam
PF00825 Ribonuclease_P, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD003629 Ribonuclease_P, 1 hit
SUPFAMiSSF54211 SSF54211, 1 hit
PROSITEiView protein in PROSITE
PS00648 RIBONUCLEASE_P, 1 hit

Sequencei

Sequence statusi: Complete.

Q8KGG4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYPGMLSEKR TNALPRGEIA RGKSAVSRLF SQGGRLKGGF LLLIYSASRP
60 70 80 90 100
VEQAPRIPVR VLFTVGKKLV PRAVDRNRIK RLMREAYRLE KNILTRALAF
110 120 130 140 150
DAGKGDHQVM LAFLYRARAD AIPSLERFRA EIRHMLKNLL SNRLPQTREG

DRIE
Length:154
Mass (Da):17,584
Last modified:October 1, 2002 - v1
Checksum:iF6D5112EA43686DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006470 Genomic DNA Translation: AAM71252.1
RefSeqiNP_660910.1, NC_002932.3
WP_010931698.1, NC_002932.3

Genome annotation databases

EnsemblBacteriaiAAM71252; AAM71252; CT0004
GeneIDi1006128
KEGGicte:CT0004
PATRICifig|194439.7.peg.4

Similar proteinsi

Entry informationi

Entry nameiRNPA_CHLTE
AccessioniPrimary (citable) accession number: Q8KGG4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2002
Last sequence update: October 1, 2002
Last modified: March 28, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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