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Q8KGG4

- RNPA_CHLTE

UniProt

Q8KGG4 - RNPA_CHLTE

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Protein
Ribonuclease P protein component
Gene
rnpA, CT0004
Organism
Chlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme By similarity.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC
  2. tRNA binding Source: InterPro

GO - Biological processi

  1. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciCTEP194439:GHN0-4-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component (EC:3.1.26.5)
Short name:
RNase P protein
Short name:
RNaseP protein
Alternative name(s):
Protein C5
Gene namesi
Name:rnpA
Ordered Locus Names:CT0004
OrganismiChlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS)
Taxonomic identifieri194439 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobaculum
ProteomesiUP000001007: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 154154Ribonuclease P protein componentUniRule annotation
PRO_0000198447Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit By similarity.

Protein-protein interaction databases

STRINGi194439.CT0004.

Structurei

3D structure databases

ProteinModelPortaliQ8KGG4.

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.

Phylogenomic databases

eggNOGiNOG41814.
HOGENOMiHOG000155258.
KOiK03536.
OMAiICIVAAD.
OrthoDBiEOG6XWV8K.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
HAMAPiMF_00227. RNase_P.
InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
[Graphical view]
PfamiPF00825. Ribonuclease_P. 1 hit.
[Graphical view]
ProDomiPD003629. Ribonuclease_P. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54211. SSF54211. 1 hit.
PROSITEiPS00648. RIBONUCLEASE_P. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8KGG4-1 [UniParc]FASTAAdd to Basket

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MYPGMLSEKR TNALPRGEIA RGKSAVSRLF SQGGRLKGGF LLLIYSASRP    50
VEQAPRIPVR VLFTVGKKLV PRAVDRNRIK RLMREAYRLE KNILTRALAF 100
DAGKGDHQVM LAFLYRARAD AIPSLERFRA EIRHMLKNLL SNRLPQTREG 150
DRIE 154
Length:154
Mass (Da):17,584
Last modified:October 1, 2002 - v1
Checksum:iF6D5112EA43686DD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006470 Genomic DNA. Translation: AAM71252.1.
RefSeqiNP_660910.1. NC_002932.3.
WP_010931698.1. NC_002932.3.

Genome annotation databases

EnsemblBacteriaiAAM71252; AAM71252; CT0004.
GeneIDi1006128.
KEGGicte:CT0004.
PATRICi21398109. VBIChlTep116050_0004.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006470 Genomic DNA. Translation: AAM71252.1 .
RefSeqi NP_660910.1. NC_002932.3.
WP_010931698.1. NC_002932.3.

3D structure databases

ProteinModelPortali Q8KGG4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 194439.CT0004.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM71252 ; AAM71252 ; CT0004 .
GeneIDi 1006128.
KEGGi cte:CT0004.
PATRICi 21398109. VBIChlTep116050_0004.

Phylogenomic databases

eggNOGi NOG41814.
HOGENOMi HOG000155258.
KOi K03536.
OMAi ICIVAAD.
OrthoDBi EOG6XWV8K.

Enzyme and pathway databases

BioCyci CTEP194439:GHN0-4-MONOMER.

Family and domain databases

Gene3Di 3.30.230.10. 1 hit.
HAMAPi MF_00227. RNase_P.
InterProi IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
[Graphical view ]
Pfami PF00825. Ribonuclease_P. 1 hit.
[Graphical view ]
ProDomi PD003629. Ribonuclease_P. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF54211. SSF54211. 1 hit.
PROSITEi PS00648. RIBONUCLEASE_P. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49652 / DSM 12025 / TLS.

Entry informationi

Entry nameiRNPA_CHLTE
AccessioniPrimary (citable) accession number: Q8KGG4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2002
Last sequence update: October 1, 2002
Last modified: September 3, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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