Q8KG91 (Q8KG91_CHLTE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pyrroline-5-carboxylate reductase RuleBase RU003903
EC=1.5.1.2 RuleBase RU003903

Gene names

Name:	proC EMBL AAM71325.1
Ordered Locus Names:	CT0077

Organism

Chlorobium tepidum

Taxonomic identifier

1097 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobaculum

Protein attributes

Sequence length	266 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H. RuleBase RU003903
Pathway	Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1. RuleBase RU003903
Sequence similarities	Belongs to the pyrroline-5-carboxylate reductase family. RuleBase RU003903

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Proline biosynthesis RuleBase RU003903
Ligand	NADP RuleBase RU003903
Molecular function	Oxidoreductase RuleBase RU003903 EMBL AAM71325.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proline biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro pyrroline-5-carboxylate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8KG91 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 2C0E8C4B5FA9C58D	FASTA	266	27,906
	10 20 30 40 50 60 MARLSIGFIG TGRIAQALIS GLSHDPNIVI CGYDKMPDAL HSVSLQYGVN TEESIESLAR 70 80 90 100 110 120 DAEIIVIAVK PYQMAEVLAE LKPALHGQHL IVSVAAGIST GFIESNCPEG TRVVRVMPNT 130 140 150 160 170 180 PAFVGEGMTA LCKGMHATAD DLLVAERIFN AIGKTAIIEE SGMDAATAVS GSGPAYMFRI 190 200 210 220 230 240 IDSLAEGGEA CGLDRETAQL LAAQTMLGAA KMVLSGHKSP EELVREVTTP GGTTEAGLKA 250 260 MDERDLRGAL IDTVRAAAAR SKELMK

References

[1]

"The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium." Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M., Dodson R.J., DeBoy R.T., Gwinn M.L., Nelson W.C., Haft D.H., Hickey E.K., Peterson J.D., Durkin A.S., Kolonay J.F., Yang F., Holt I.E., Umayam L.A., Mason T.M. , Brenner M., Shea T.P., Parksey D.S., Nierman W.C., Feldblyum T.V., Hansen C.L., Craven M.B., Radune D., Vamathevan J.J., Khouri H.M., White O., Gruber T.M., Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002) [PubMed: 12093901] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49652 / DSM 12025 / TLS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE006470 Genomic DNA. Translation: AAM71325.1.
RefSeq	NP_660983.1. NC_002932.3.
3D structure databases
ProteinModelPortal	Q8KG91.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1006498.
GenomeReviews	Gene locus CT0077 in contig AE006470_GR.
KEGG	cte:CT0077.
NMPDR	fig|194439.1.peg.77.
PATRIC	21398257. VBIChlTep116050_0077.
TIGR	CT0077.
Phylogenomic databases
HOGENOM	HBG726602.
OMA	RTFNEHQ.
ProtClustDB	CLSK637145.
Family and domain databases
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR016040. NAD(P)-bd_dom. IPR004455. NADP_OxRdtase_F420. IPR000304. Pyrroline-COOH_reductase. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00286.
PANTHER	PTHR11645. P5CR. 1 hit.
Pfam	PF03807. F420_oxidored. 1 hit. [Graphical view]
PIRSF	PIRSF000193. Pyrrol-5-carb_rd. 1 hit.
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR00112. ProC. 1 hit.
PROSITE	PS00521. P5CR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8KG91_CHLTE

Accession

Primary (citable) accession number: Q8KG91

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	December 14, 2011
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)