SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8KG38

- GLMS_CHLTE

UniProt

Q8KG38 - GLMS_CHLTE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
Gene
glmS, CT0130
Organism
Chlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source By similarity.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activity By similarity
Active sitei609 – 6091For Fru-6P isomerization activity By similarity

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate biosynthetic process Source: InterPro
  2. glutamine metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

BioCyciCTEP194439:GHN0-132-MONOMER.

Protein family/group databases

MEROPSiC44.971.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC:2.6.1.16)
Alternative name(s):
D-fructose-6-phosphate amidotransferase
GFAT
Glucosamine-6-phosphate synthase
Hexosephosphate aminotransferase
L-glutamine--D-fructose-6-phosphate amidotransferase
Gene namesi
Name:glmS
Ordered Locus Names:CT0130
OrganismiChlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS)
Taxonomic identifieri194439 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobaculum
ProteomesiUP000001007: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 614613Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation
PRO_0000135320Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi194439.CT0130.

Structurei

3D structure databases

ProteinModelPortaliQ8KG38.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 223222Glutamine amidotransferase type-2
Add
BLAST
Domaini292 – 431140SIS 1
Add
BLAST
Domaini463 – 604142SIS 2
Add
BLAST

Sequence similaritiesi

Contains 2 SIS domains.

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiCOG0449.
HOGENOMiHOG000258898.
KOiK00820.
OMAiPVTRRFM.
OrthoDBiEOG6KT2Q1.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
HAMAPiMF_00164. GlmS.
InterProiIPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
PfamiPF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01135. glmS. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8KG38-1 [UniParc]FASTAAdd to Basket

« Hide

MCGIIGYIGR REAAPLLLNG LKRLEYRGYD SAGMAVLNGS MKMLKKKGSV    50
SNLEELLNVS GTVMLGATVG IAHTRWATHG DPSDRNAHPH MNVSGDIALI 100
HNGIIENYSA LKQELMGEGY VFESDTDSEV LVHLIDRIWK NDSALGLEGA 150
VRQALRHVEG AYGICVVSSR EPDKIVVARK GSPLVIGLGD GEFFIASDAA 200
PIVEHTNKVV YLSDGEMAVV TRDSYTVKTI ENVEQQKRVT ELDFSLEKIE 250
KGGFEHFMLK EIFEQPEVMR DVMRGRVRVE EGRVHLGGIH DYLDRLKQAK 300
RIMICACGTS WHAGLIGEYL IEEFARIPVE VDYASEFRYR NPIVSSDDVV 350
IVISQSGETA DTLAALRLAK EKGAMVMGIC NVVGSTIPRE TLCGMYTHAG 400
PEVGVASTKA FTAQVIVLFM LAMALSKGRT ISQEEIKLNL RELAEVPDKV 450
AWILEQNDAI KEIAVKLKDA RNALYLGRGY NFPVALEGAL KLKEISYIHA 500
EGYPAAEMKH GPIALIDEDM PVIVIATRDN TYAKILSNIE EVRSRKGRVI 550
AIASEGDREI ERLTEDVIYI PQASAAVLPL LTVIPLQLLS YHVATLRGCN 600
VDRPRNLAKS VTVE 614
Length:614
Mass (Da):67,577
Last modified:January 23, 2007 - v3
Checksum:iA9B4195C3DC3F84F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006470 Genomic DNA. Translation: AAM71378.1.
RefSeqiNP_661036.1. NC_002932.3.
WP_010931824.1. NC_002932.3.

Genome annotation databases

EnsemblBacteriaiAAM71378; AAM71378; CT0130.
GeneIDi1006837.
KEGGicte:CT0130.
PATRICi21398359. VBIChlTep116050_0127.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006470 Genomic DNA. Translation: AAM71378.1 .
RefSeqi NP_661036.1. NC_002932.3.
WP_010931824.1. NC_002932.3.

3D structure databases

ProteinModelPortali Q8KG38.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 194439.CT0130.

Protein family/group databases

MEROPSi C44.971.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM71378 ; AAM71378 ; CT0130 .
GeneIDi 1006837.
KEGGi cte:CT0130.
PATRICi 21398359. VBIChlTep116050_0127.

Phylogenomic databases

eggNOGi COG0449.
HOGENOMi HOG000258898.
KOi K00820.
OMAi PVTRRFM.
OrthoDBi EOG6KT2Q1.

Enzyme and pathway databases

BioCyci CTEP194439:GHN0-132-MONOMER.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
HAMAPi MF_00164. GlmS.
InterProi IPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
Pfami PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01135. glmS. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49652 / DSM 12025 / TLS.

Entry informationi

Entry nameiGLMS_CHLTE
AccessioniPrimary (citable) accession number: Q8KG38
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 25, 2002
Last sequence update: January 23, 2007
Last modified: September 3, 2014
This is version 80 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi