Reviewed, UniProtKB/Swiss-Prot Q8KFN8 (MURI_CHLTE)

Names and origin

Protein names

Recommended name:
    Glutamate racemase
    EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	CT0284

Organism

Chlorobium tepidum [Complete proteome] [HAMAP]

Taxonomic identifier

1097 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobaculum

Protein attributes

Sequence length	272 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity.
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 272	272	Glutamate racemase HAMAP MF_00258		PRO_0000095464

Sequences

	Sequence		Length	Mass (Da)
	Q8KFN8-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: E882A0D8D745A06C	FASTA	272	29,225
	10 20 30 40 50 60 MPQHKVSSDS PIGIFDSGIG GLTVVKAVQA ALPSERIIYF GDTARVPYGS KSQVTIRKYA 70 80 90 100 110 120 REDTELLMKH QPKLIIVACN TVSALALDVV EQTAGGIPVI GVLKAGAELA VQKTKSGRIG 130 140 150 160 170 180 VIGTQATIGS NAYTCAIREE KETLEVFPKA CPLFVPLAEE GFIDHPATRL VAEEYLAAFT 190 200 210 220 230 240 GKEIDTLVLG CTHYPILRKI IESITGPEIT IIDSAEAVAS KAGELLAARG LLNQSPEKAL 250 260 270 PHLMVSDLPQ KFRELYRLFM GTELPDVELV GM

References

[1]

"The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium." Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M., Dodson R.J., DeBoy R.T., Gwinn M.L., Nelson W.C., Haft D.H., Hickey E.K., Peterson J.D., Durkin A.S., Kolonay J.F., Yang F., Holt I.E., Umayam L.A., Mason T.M. , Brenner M., Shea T.P., Parksey D.S., Nierman W.C., Feldblyum T.V., Hansen C.L., Craven M.B., Radune D., Vamathevan J.J., Khouri H.M., White O., Gruber T.M., Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002) [PubMed: 12093901] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49652 / DSM 12025 / TLS.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE006470 Genomic DNA. Translation: AAM71530.1.
RefSeq	NP_661188.1.
3D structure databases
HSSP	HSSP built from PDB template 1B74 based on UniProtKB P56868.
ModBase	Search...
Genome annotation databases
GeneID	1007856.
GenomeReviews	Gene locus CT0284 in contig AE006470_GR.
KEGG	cte:CT0284.
NMPDR	fig|194439.1.peg.282.
TIGR	CT0284.
Phylogenomic databases
HOGENOM	Q8KFN8.
OMA	VACNTAA.
Enzyme and pathway databases
BioCyc	CTEP194439:CT_0284-MON.
BRENDA	5.1.1.3. 189605.
Family and domain databases
HAMAP	MF_00258. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
TIGRFAMs	TIGR00067. glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. False negative. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_CHLTE

Accession

Primary (citable) accession number: Q8KFN8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 25, 2002
Last sequence update:	October 1, 2002
Last modified:	November 3, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)