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Q8KFJ7 (UPPP_CHLTE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:CT0329
OrganismChlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS) [Reference proteome] [HAMAP]
Taxonomic identifier194439 [NCBI]
Taxonomic lineageBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobaculum

Protein attributes

Sequence length282 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 282282Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000151131

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane40 – 6021Helical; Potential
Transmembrane89 – 10921Helical; Potential
Transmembrane112 – 13221Helical; Potential
Transmembrane153 – 17321Helical; Potential
Transmembrane196 – 21621Helical; Potential
Transmembrane228 – 24821Helical; Potential
Transmembrane258 – 27821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q8KFJ7 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 8231A028E2C17C19

FASTA28230,197
        10         20         30         40         50         60 
MNLFQAIILG IIQGLTEFLP ISSSAHLRIV PALMGWGDPG AAFTAIIQIG TLAAVLIYFA 

        70         80         90        100        110        120 
KDIVSISGAV ISGLVKGKPL GTDEARTGWM IAVGTIPIVV FGLTFKHEIE TVLRSLYIVS 

       130        140        150        160        170        180 
ASMIGLALVL VVAEKHTANR ARDGRRGKSI NELSWTDAII IGLAQAMALI PGSSRSGVTI 

       190        200        210        220        230        240 
TGGLFRNLDR ETAARFSFLL SLPSVFAAGM LELYQTRQEI MSSTHNMLNL AVATIAAFIF 

       250        260        270        280 
GYLSIAFLLN YLKRHTTGIF IAYRLILGIG LIVMIGTGHL LP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006470 Genomic DNA. Translation: AAM71575.1.
RefSeqNP_661233.1. NC_002932.3.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING194439.CT0329.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM71575; AAM71575; CT0329.
GeneID1007991.
KEGGcte:CT0329.
PATRIC21398775. VBIChlTep116050_0319.

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAFNDAHAK.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycCTEP194439:GHN0-347-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_CHLTE
AccessionPrimary (citable) accession number: Q8KFJ7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 25, 2002
Last sequence update: October 1, 2002
Last modified: May 14, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families