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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) (Chlorobium tepidum)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BioCyciCTEP194439:G1FZE-364-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:CT0346
OrganismiChlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) (Chlorobium tepidum)
Taxonomic identifieri194439 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobaculum
Proteomesi
  • UP000001007 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002072121 – 194Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST194

Proteomic databases

PRIDEiQ8KFI0

Interactioni

Protein-protein interaction databases

STRINGi194439.CT0346

Structurei

3D structure databases

ProteinModelPortaliQ8KFI0
SMRiQ8KFI0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102326
KOiK00684
OMAiYRQGIFP
OrthoDBiPOG091H045I

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

Q8KFI0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKVEDILRA YRHGFFPMAD SREGTVSWCQ PYQRAVVPLD SFRPSRSLRR
60 70 80 90 100
VIGKKRFTIK INSVFEQVIR ACSQPRSTGQ ETWLSEEIIK VFLKLHRLGV
110 120 130 140 150
AHSVESWQDG ELAGGLYGLS MGGAFFGESM FFFRSDASKV AFAWLVGYLK
160 170 180 190
RKGYLLLDAQ IMNPHLESLG AIEIPHEEYM VQLERALGKK ISFV
Length:194
Mass (Da):22,136
Last modified:October 1, 2002 - v1
Checksum:i55A6DC4E87AB984E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006470 Genomic DNA Translation: AAM71592.1
RefSeqiNP_661250.1, NC_002932.3
WP_010932038.1, NC_002932.3

Genome annotation databases

EnsemblBacteriaiAAM71592; AAM71592; CT0346
GeneIDi1008008
KEGGicte:CT0346
PATRICifig|194439.7.peg.335

Similar proteinsi

Entry informationi

Entry nameiLFTR_CHLTE
AccessioniPrimary (citable) accession number: Q8KFI0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: October 1, 2002
Last modified: March 28, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health