Q8KFH6 (Q8KFH6_CHLTE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADH] PIRNR PIRNR000094
EC=1.3.1.9 PIRNR PIRNR000094

Gene names

Name:	fabI EMBL AAM71596.1
Ordered Locus Names:	CT0350

Organism

Chlorobium tepidum

Taxonomic identifier

1097 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobaculum

Protein attributes

Sequence length	293 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH. PIRNR PIRNR000094
Pathway	Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Ontologies

Keywords
Biological process	Fatty acid biosynthesis PIRNR PIRNR000094 Lipid synthesis
Ligand	NAD PIRNR PIRNR000094
Molecular function	Oxidoreductase PIRNR PIRNR000094 EMBL AAM71596.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	164	1	Proton acceptor By similarity PIRSR PIRSR000094-1

Sequences

	Sequence		Length	Mass (Da)
	Q8KFH6 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: D6427D83B3DAE03D	FASTA	293	32,445
	10 20 30 40 50 60 MPEKAHYGLL KGKKGIVFGP LDESSIGWQI ALHAYREGAQ VALSNVATAI RFGKLQELSE 70 80 90 100 110 120 LCGNAPILIC DASKNEEVDN TFRELKETMG SVDFIVHSIG MSQNIRKQVP YEELNYEWFM 130 140 150 160 170 180 RTLDVSGISF HRLVAYALKN EALNDGASIV ALSYIASQRN YWTYSDMGDA KSLLESIARS 190 200 210 220 230 240 FGPRLAPRGI RINTISQSPT YTKAGSGIPG FEKMYDYSEL MSPLGNASAE ECAEYTMTIL 250 260 270 280 290 SDLTRKVTMQ NLFHDGGYSS MGATIPMIKL AHEALHDKEL AERVGLEGRH SSR

References

[1]

"The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium." Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M., Dodson R.J., DeBoy R.T., Gwinn M.L., Nelson W.C., Haft D.H., Hickey E.K., Peterson J.D., Durkin A.S., Kolonay J.F., Yang F., Holt I.E., Umayam L.A., Mason T.M. , Brenner M., Shea T.P., Parksey D.S., Nierman W.C., Feldblyum T.V., Hansen C.L., Craven M.B., Radune D., Vamathevan J.J., Khouri H.M., White O., Gruber T.M., Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002) [PubMed: 12093901] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49652 / DSM 12025 / TLS.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE006470 Genomic DNA. Translation: AAM71596.1.
RefSeq	NP_661254.1. NC_002932.3.
3D structure databases
HSSP	HSSP built from PDB template 1DFI based on UniProtKB P29132.
ProteinModelPortal	Q8KFH6.
ModBase	Search...
Proteomic databases
PRIDE	Q8KFH6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1008012.
GenomeReviews	Gene locus CT0350 in contig AE006470_GR.
KEGG	cte:CT0350.
NMPDR	fig|194439.1.peg.348.
PATRIC	21398815. VBIChlTep116050_0339.
TIGR	CT0350.
Phylogenomic databases
HOGENOM	HBG750976.
OMA	NATAEEC.
ProtClustDB	CLSK813438.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR014358. Enoyl-ACP_Rdtase_NADH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00208.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PIRSF	PIRSF000094. Enoyl-ACP_rdct. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8KFH6_CHLTE

Accession

Primary (citable) accession number: Q8KFH6

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2002
Last sequence update:	October 1, 2002
Last modified:	December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)