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Q8KDQ7 (G6PI_CHLTE) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:CT0988
OrganismChlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS) [Reference proteome] [HAMAP]
Taxonomic identifier194439 [NCBI]
Taxonomic lineageBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobaculum

Protein attributes

Sequence length559 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 559559Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180623

Sites

Active site3521Proton donor By similarity
Active site3831 By similarity
Active site5111 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8KDQ7 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 8EC0A13F91C120D1

FASTA55963,089
        10         20         30         40         50         60 
MYLSRSAEWS ALESHYQDIS HQAMIDLFST DPNRHERFSL SFNAIHLDYS KNRISARTME 

        70         80         90        100        110        120 
LLMDLVRRSG IEKKRRQMFE GEQINFTEHR SVLHTALRRP PGYTMTIDGN DVASEVSDVL 

       130        140        150        160        170        180 
DQMKAFCKKV ISGEWKGYTG KRITDVVNIG IGGSDLGPFM VTEALKPFAH GKLKVHFVSN 

       190        200        210        220        230        240 
VDGSHLVETL RGLNPETTLF IIASKTFTTQ ETLANAVSAR AWFLVKAGNR DHVAKHFVAV 

       250        260        270        280        290        300 
STNREKVEEF GIDPDNMFRF WDWVGGRYSL WSAIGLSIAL YLGFDRFREL LAGAHAMDEH 

       310        320        330        340        350        360 
FLNAPLEENM PMILAMLGIW YNNFFGAHSQ AIIPYDQYLH RFPAYLQQLD MESNGKRVDR 

       370        380        390        400        410        420 
AGHEVDYATG PVIWGEPGTN AQHAFFQLLH QGTEIVPVDF IVSLKSQNPV GEHHDMLVAN 

       430        440        450        460        470        480 
CFAQSEALMK GKSEAEARAE LEAAGLSGGD LEKLLPHKLF PGNRPTNTIV LDELNPFNLG 

       490        500        510        520        530        540 
SLIALYEHKV FVQGVVWNIN SFDQWGVELG KQLAKAILPE FDAVDPVETH DASTNALINR 

       550 
YRQFRNGLKF PKSNQLKMF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006470 Genomic DNA. Translation: AAM72223.1.
RefSeqNP_661881.1. NC_002932.3.

3D structure databases

ProteinModelPortalQ8KDQ7.
SMRQ8KDQ7. Positions 3-545.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING194439.CT0988.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM72223; AAM72223; CT0988.
GeneID1007039.
KEGGcte:CT0988.
PATRIC21399975. VBIChlTep116050_0899.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMANCHFVAN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycCTEP194439:GHN0-1025-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_CHLTE
AccessionPrimary (citable) accession number: Q8KDQ7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 27, 2003
Last sequence update: October 1, 2002
Last modified: June 11, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways