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Q8KCT7 (SYD_CHLTE) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aspartate--tRNA ligase
EC=6.1.1.12
Alternative name(s):
Aspartyl-tRNA synthetase
Short name=AspRS
Gene names
Name:aspS
Ordered Locus Names:CT1323
OrganismChlorobium tepidum
Taxonomic identifier1097 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobaculum

Protein attributes

Sequence length603 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). HAMAP MF_00044_B

Subunit structure

Homodimer By similarity. HAMAP MF_00044_B

Subcellular location

Cytoplasm HAMAP MF_00044_B.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processtRNA aminoacylation for protein translation

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

aspartate-tRNA ligase activity

Inferred from electronic annotation. Source: EC

nucleic acid binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 603603Aspartate--tRNA ligase HAMAP MF_00044_B
PRO_0000110855

Sequences

Sequence LengthMass (Da)Tools
Q8KCT7 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 6F43978ABCB29877

FASTA60368,599
        10         20         30         40         50         60 
MSKEPTTADG LQNRFRTHYC GRLNRKSEGE LVRIAGWVHR IRDHGGLIFI DLRDHTGICQ 

        70         80         90        100        110        120 
LVVLPENESQ FKLAETLHSE SVISAEGKVV LRSDETVNPR LASGAIEVVV SSIQIESNAD 

       130        140        150        160        170        180 
PLPFPVADDM PTSEELRLKY RFLDLRREKL HENIIFRSKL TAAVRKYLTD LDFIEIQTPI 

       190        200        210        220        230        240 
LTSSSPEGAR DFLVPSRLHP GKFYALPQAP QQFKQLLMVA GFPRYFQIAP CFRDEDARAD 

       250        260        270        280        290        300 
RSPGEFYQID IEMSFIEQDD LFVILEGMFK HLVENMSHKR ITQFPFPRIS YKDVMNRYGS 

       310        320        330        340        350        360 
DKPDLRIPLE IQDVTELFVN SGFKVFASNT AEGSCVKAMV LKGMGNESRL FYDKAEKRAR 

       370        380        390        400        410        420 
ELGSAGLAYI QFKEEGPKGP VVKFLSEAEM NALKERLGIV TGDVVFFGAG KWEKTCKIMG 

       430        440        450        460        470        480 
GMRNYFADLF PLDKDELSFC WIVDFPMFEY NEEDKKIDFS HNPFSMPQGE MEALESKFPL 

       490        500        510        520        530        540 
DILAYQYDIV CNGIELSSGA IRNHRPDIMY KAFEIAGYSK EEVDARFGHM IEAFKHGAPP 

       550        560        570        580        590        600 
HGGIAPGLDR LVMILRDEQN IREVIAFPMN QSAQDLMMAA PSEVTAQQLK ELCIRIELPE 


EEK

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE006470 Genomic DNA. Translation: AAM72553.1.
RefSeqNP_662211.1. NC_002932.3.

3D structure databases

ProteinModelPortalQ8KCT7.
ModBaseSearch...

Proteomic databases

PRIDEQ8KCT7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1006692.
GenomeReviewsGene locus CT1323 in contig AE006470_GR.
KEGGcte:CT1323.
NMPDRfig|194439.1.peg.1305.
PATRIC21400597. VBIChlTep116050_1204.
TIGRCT1323.

Phylogenomic databases

HOGENOMHBG396032.
OMAYQLDVEM.
ProtClustDBPRK00476.

Enzyme and pathway databases

BioCycCTEP194439:CT_1323-MONOMER.

Family and domain databases

HAMAPMF_00044_B. Asp_tRNA_synth_B.
[Tree]
InterProIPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR004524. Asp-tRNA-synth_IIb_bac/mt.
IPR002312. Asp/Asn-tRNA-synth_IIb.
IPR004115. GAD_dom.
IPR012340. NA-bd_OB-fold.
IPR016027. NA-bd_OB-fold-like.
IPR004365. NA-bd_OB_tRNA-helicase.
[Graphical view]
Gene3DG3DSA:3.30.1360.30. GAD_dom. 1 hit.
G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KOK01876.
PANTHERPTHR22594. aa-tRNA-synt_II. 1 hit.
PTHR22594:SF5. AspS_bac. 1 hit.
PfamPF02938. GAD. 1 hit.
PF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti. 1 hit.
[Graphical view]
PRINTSPR01042. TRNASYNTHASP.
SUPFAMSSF50249. Nucleic_acid_OB. 1 hit.
SSF55261. SSF55261. 1 hit.
TIGRFAMsTIGR00459. AspS_bact. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYD_CHLTE
AccessionPrimary (citable) accession number: Q8KCT7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 27, 2003
Last sequence update: October 1, 2002
Last modified: January 25, 2012
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries

SIMILARITY comments

Index of protein domains and families

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