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Q8KCI9 (AROC_CHLTE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chorismate synthase

EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:CT1432
OrganismChlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS) [Reference proteome] [HAMAP]
Taxonomic identifier194439 [NCBI]
Taxonomic lineageBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobaculum

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP-Rule MF_00300

Cofactor

Reduced flavin By similarity. HAMAP-Rule MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP-Rule MF_00300

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

chorismate biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionchorismate synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Chorismate synthase HAMAP-Rule MF_00300
PRO_0000140574

Sequences

Sequence LengthMass (Da)Tools
Q8KCI9 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 2D556ACD8B85217A

FASTA39742,278
        10         20         30         40         50         60 
MIRYFTAGES HGPALSAIVE GMPAGVALTE SDINDQLARR QQGYGRGGRM KIETDRAEVL 

        70         80         90        100        110        120 
SGVRFGKTIG SPVAMLIRNR DWENWTTSMA QFEDHATEVQ KITIPRPGHA DLTGFVKYGF 

       130        140        150        160        170        180 
DDIRPVIDRS SARETAARVA AGSLARAFLR QLGIQIGSYI STIGPVSEAA APASLQELLD 

       190        200        210        220        230        240 
AGAESLAAEA DKSPVRMLDP EAETAAIAAI DQAKADGDTL GGIVELYITG VPMGLGSYVQ 

       250        260        270        280        290        300 
HDRRLDSELA AAIMSIQAIK GVEIGPAFDN ARKPGSQVHD ELFAGGEKGL RRETNRAGGI 

       310        320        330        340        350        360 
EGSMSSGQPI HIRAAMKPIS SLVSPLSSFD LATLEAVQSR FERSDTCAVP AAGVVAEAVV 

       370        380        390 
APVIANALLE KLGGDHMAEI KERLEVYRAA LRMRFEK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006470 Genomic DNA. Translation: AAM72660.1.
RefSeqNP_662318.1. NC_002932.3.

3D structure databases

ProteinModelPortalQ8KCI9.
SMRQ8KCI9. Positions 1-394.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING194439.CT1432.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM72660; AAM72660; CT1432.
GeneID1005980.
KEGGcte:CT1432.
PATRIC21400791. VBIChlTep116050_1300.

Phylogenomic databases

eggNOGCOG0082.
HOGENOMHOG000060334.
KOK01736.
OMAYMRDLKK.
OrthoDBEOG6WDSHT.

Enzyme and pathway databases

BioCycCTEP194439:GHN0-1471-MONOMER.
UniPathwayUPA00053; UER00090.

Family and domain databases

Gene3D3.60.150.10. 1 hit.
HAMAPMF_00300. Chorismate_synth.
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
PANTHERPTHR21085. PTHR21085. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. SSF103263. 1 hit.
TIGRFAMsTIGR00033. aroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_CHLTE
AccessionPrimary (citable) accession number: Q8KCI9
Entry history
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: October 1, 2002
Last modified: May 14, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways