Q8KC69 (SURE_CHLTE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	CT1557

Organism

Chlorobium tepidum

Taxonomic identifier

1097 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobaculum

Protein attributes

Sequence length	263 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 263	263	5'-nucleotidase surE HAMAP MF_00060		PRO_0000111803
Sites
	Metal binding	15	1	Divalent metal cation By similarity
	Metal binding	16	1	Divalent metal cation By similarity
	Metal binding	46	1	Divalent metal cation By similarity
	Metal binding	102	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8KC69 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 67F91925FDB774C7	FASTA	263	29,242
	10 20 30 40 50 60 MTTKPQKPHI LVCNDDGIEG LGLHALAASM KKLGSVTVVA PAEPQSGKSH GMTLGEPLRI 70 80 90 100 110 120 RRYQKNNRFF GYTVSGTPVD CIKVALSHIL DAKPDLIVSG INYGSNTAMN SLYSGTVAAA 130 140 150 160 170 180 REGAIQNVPS LAFSLTTYEN ADFTYAAKFA RQLAREVLRR GMPPDTILSA NIPNVPEKEI 190 200 210 220 230 240 RGILFTRQGR SRWEESTIER HDMYGNPYYW LAGSLQLHDN DLAEDEYAVR HNYVAVTPIT 250 260 CDMTDHRFRS ELETWGLQNT IKK

References

[1]

"The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium." Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M., Dodson R.J., DeBoy R.T., Gwinn M.L., Nelson W.C., Haft D.H., Hickey E.K., Peterson J.D., Durkin A.S., Kolonay J.F., Yang F., Holt I.E., Umayam L.A., Mason T.M. , Brenner M., Shea T.P., Parksey D.S., Nierman W.C., Feldblyum T.V., Hansen C.L., Craven M.B., Radune D., Vamathevan J.J., Khouri H.M., White O., Gruber T.M., Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002) [PubMed: 12093901] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49652 / DSM 12025 / TLS.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE006470 Genomic DNA. Translation: AAM72782.1.
RefSeq	NP_662440.1. NC_002932.3.
3D structure databases
ProteinModelPortal	Q8KC69.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1007226.
GenomeReviews	Gene locus CT1557 in contig AE006470_GR.
KEGG	cte:CT1557.
NMPDR	fig|194439.1.peg.1534.
PATRIC	21401011. VBIChlTep116050_1410.
TIGR	CT1557.
Phylogenomic databases
HOGENOM	HBG600532.
OMA	SINVIYS.
ProtClustDB	PRK13932.
Enzyme and pathway databases
BioCyc	CTEP194439:CT_1557-MONOMER.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_CHLTE

Accession

Primary (citable) accession number: Q8KC69

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 27, 2003
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program