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Q8KC29 (Q8KC29_CHLTE) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydroorotate dehydrogenase HAMAP MF_00224
Short name=DHOD HAMAP MF_00224
Short name=DHODase HAMAP MF_00224
Short name=DHOdehase HAMAP MF_00224
EC=1.3.-.- HAMAP MF_00224
Gene names
Name:pyrDI EMBL AAM72822.1
Synonyms:pyrD HAMAP MF_00224
Ordered Locus Names:CT1597
OrganismChlorobium tepidum
Taxonomic identifier1097 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobaculum

Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of dihydroorotate to orotate By similarity. HAMAP MF_00224

Catalytic activity

(S)-dihydroorotate + acceptor = orotate + reduced acceptor. HAMAP MF_00224

Cofactor

Binds 1 FMN per subunit By similarity. HAMAP MF_00224 SAAS SAAS012135

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway. HAMAP MF_00224

Subcellular location

Cytoplasm By similarity HAMAP MF_00224.

Sequence similarities

Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. HAMAP MF_00224

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1321Nucleophile By similarity PIRSR PIRSR000164-1

Sequences

Sequence LengthMass (Da)Tools
Q8KC29 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 8C7840929B5FD8EC

FASTA30532,270
        10         20         30         40         50         60 
MNSPAAVKLG RGLNLRSPVM LASGTVSYGE ELSQLCDLSK IGGLVTKAIS PEPRTGNPPQ 

        70         80         90        100        110        120 
RIAETSCGMI NAIGLANVGL DKFVSDKVPF LQTLDTQVIV NIAGKSIDDY CQVVERLDTV 

       130        140        150        160        170        180 
EGIAAYELNL SCPNVKGECM IMGVSPDATR EIVSTLRKQT RRHLMVKLTP NVTSISAIAL 

       190        200        210        220        230        240 
AAEEAGADSV SLINTVVGMA VDYRKRKPLL KNVTGGLSGP AIKPIALAKV WEVSKAVKIP 

       250        260        270        280        290        300 
IVGMGGIASF SDAMEFLLVG ASAIQIGTMN FVYPDIGEKI AVAIDKFFSQ PDAPAFQEYV 


GSLMV

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE006470 Genomic DNA. Translation: AAM72822.1.
RefSeqNP_662480.1. NC_002932.3.

3D structure databases

HSSPHSSP built from PDB template 1EP2 based on UniProtKB P54322.
ProteinModelPortalQ8KC29.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1006098.
GenomeReviewsGene locus CT1597 in contig AE006470_GR.
KEGGcte:CT1597.
NMPDRfig|194439.1.peg.1574.
PATRIC21401079. VBIChlTep116050_1444.
TIGRCT1597.

Phylogenomic databases

HOGENOMHBG472415.
OMAVALRMVW.
ProtClustDBCLSK637846.

Family and domain databases

HAMAPMF_00224. DHO_dh_type1.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR005720. Dihydroorotate_DH.
IPR024920. Dihydroorotate_DH_1.
IPR012135. Dihydroorotate_DH_1_2.
IPR001295. Dihydroorotate_DH_CS.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK00226.
PfamPF01180. DHO_dh. 1 hit.
[Graphical view]
PIRSFPIRSF000164. DHO_oxidase. 1 hit.
TIGRFAMsTIGR01037. PyrD_sub1_fam. 1 hit.
PROSITEPS00912. DHODEHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ8KC29_CHLTE
AccessionPrimary (citable) accession number: Q8KC29
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2002
Last sequence update: October 1, 2002
Last modified: January 25, 2012
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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