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Q8KAE1

- PGK_CHLTE

UniProt

Q8KAE1 - PGK_CHLTE

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Chlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei37 – 371SubstrateUniRule annotation
    Binding sitei119 – 1191SubstrateUniRule annotation
    Binding sitei152 – 1521SubstrateUniRule annotation
    Binding sitei203 – 2031ATPUniRule annotation
    Binding sitei294 – 2941ATP; via carbonyl oxygenUniRule annotation
    Binding sitei325 – 3251ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi354 – 3574ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCTEP194439:GHN0-2270-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:CT2222
    OrganismiChlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS)
    Taxonomic identifieri194439 [NCBI]
    Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobaculum
    ProteomesiUP000001007: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 397397Phosphoglycerate kinasePRO_0000145928Add
    BLAST

    Proteomic databases

    PRIDEiQ8KAE1.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi194439.CT2222.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8KAE1.
    SMRiQ8KAE1. Positions 1-397.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni21 – 233Substrate bindingUniRule annotation
    Regioni60 – 634Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227108.
    KOiK00927.
    OMAiFPVDYVT.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8KAE1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQKKTLSDIS LQGKRVLMRV DFNVPLDQDR NITDEKRIVE ALPSIRKVID    50
    NGGRLILMSH LGRPKGKVNP AFSLSPVAKR LSELLDCPVT MAGDCIGTEV 100
    MQQVLALQDG DVLMLENLRF HPEEEANDPD FARELASLGE IYVNDAFGTA 150
    HRAHASTEGI THFMQTAVAG YLIEKELRYL GTALNDAQRP FVAILGGAKI 200
    SGKIDVLESL FEKVDTVLVG GAMVFTFFKA QGLDVGNSLV EENKLELAVS 250
    LLEKAKAKNV RLLLPEDVVV AGEISADAPS RVEPVSAISA GMIGLDIGPA 300
    TIETYRKEIL DAKTVLWNGP MGVFEIDQFA RGTFAVAQAL ADATAEGAIT 350
    IIGGGDSAAA IAKAGLSDKV THVSTGGGAS LEFLEGKELP GIAALND 397
    Length:397
    Mass (Da):42,290
    Last modified:October 1, 2002 - v1
    Checksum:i375A08041F0224A7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006470 Genomic DNA. Translation: AAM73438.1.
    RefSeqiNP_663096.1. NC_002932.3.

    Genome annotation databases

    EnsemblBacteriaiAAM73438; AAM73438; CT2222.
    GeneIDi1007338.
    KEGGicte:CT2222.
    PATRICi21402241. VBIChlTep116050_2016.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006470 Genomic DNA. Translation: AAM73438.1 .
    RefSeqi NP_663096.1. NC_002932.3.

    3D structure databases

    ProteinModelPortali Q8KAE1.
    SMRi Q8KAE1. Positions 1-397.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 194439.CT2222.

    Proteomic databases

    PRIDEi Q8KAE1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM73438 ; AAM73438 ; CT2222 .
    GeneIDi 1007338.
    KEGGi cte:CT2222.
    PATRICi 21402241. VBIChlTep116050_2016.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227108.
    KOi K00927.
    OMAi FPVDYVT.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci CTEP194439:GHN0-2270-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 49652 / DSM 12025 / TLS.

    Entry informationi

    Entry nameiPGK_CHLTE
    AccessioniPrimary (citable) accession number: Q8KAE1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 23, 2003
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3