Reviewed, UniProtKB/Swiss-Prot Q8KA80 (EFP_BUCAP)

Names and origin

Protein names

Recommended name:
    Elongation factor P
      Short name=EF-P

Gene names

Name:	efp
Ordered Locus Names:	BUsg_021

Organism

Buchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP]

Taxonomic identifier

98794 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	187 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase By similarity.
Pathway	Protein biosynthesis; polypeptide chain elongation. HAMAP MF_00141
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the elongation factor P family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Elongation factor
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translational elongation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 187	187	Elongation factor P HAMAP MF_00141		PRO_0000094216

Sequences

	Sequence		Length	Mass (Da)
	Q8KA80-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 86C6C324DACF059D	FASTA	187	21,469
	10 20 30 40 50 60 MRVYHSNNFR SGRKIIFEKE PCLIESSEFV KPGKGQSFVR VKLRKLLTKQ LIEKTFKSTD 70 80 90 100 110 120 SLEIADVSEY TLSYLYNDGH FWYFINNNFE ELSVDKKIVG VNKKWLSEQD TCVITFWNNQ 130 140 150 160 170 180 AISITPNIFV ELKVIDTEIA LKSDTINTTT KLATLSTGAI LKVPLFIQIG SLIKVDTRSG EYVSRIK

References

[1]

"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE013218 Genomic DNA. Translation: AAM67593.1.
RefSeq	NP_660382.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1005837.
GenomeReviews	Gene locus BUsg_021 in contig AE013218_GR.
KEGG	bas:BUsg021.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8KA80.
OMA	MATYSSN
Enzyme and pathway databases
BioCyc	BAPH198804:BUSG021-MON.
Family and domain databases
HAMAP	MF_00141. [Tree]
InterPro	IPR015365. Elong-fact-P_C. IPR012340. NA-bd_OB-fold. IPR016027. NA-bd_OB-fold-like. IPR020599. Transl_elong_fac_P/YeiP. IPR013185. Transl_elong_KOW-like. IPR001059. Transl_elong_P/YeiP_cen. IPR013852. Transl_elong_P/YeiP_CS. IPR011768. Transl_elongation_fac_P. IPR014722. Transl_SH3-like_sub. IPR008991. Translation_prot_SH3-like. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 2 hits. G3DSA:2.30.30.30. Ribosomal_L2. 1 hit.
Pfam	PF01132. EFP. 1 hit. PF08207. EFP_N. 1 hit. PF09285. Elong-fact-P_C. 1 hit. [Graphical view]
PIRSF	PIRSF005901. EF-P. 1 hit.
SMART	SM00841. Elong-fact-P_C. 1 hit. [Graphical view]
TIGRFAMs	TIGR00038. efp. 1 hit.
PROSITE	PS01275. EFP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFP_BUCAP

Accession

Primary (citable) accession number: Q8KA80

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
Last sequence update:	October 1, 2002
Last modified:	November 24, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)