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Q8KA77

- FTSY_BUCAP

UniProt

Q8KA77 - FTSY_BUCAP

Protein

Signal recognition particle receptor FtsY

Gene

ftsY

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi156 – 1638GTPUniRule annotation
    Nucleotide bindingi238 – 2425GTPUniRule annotation
    Nucleotide bindingi302 – 3054GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: UniProtKB-HAMAP
    2. GTP binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. SRP-dependent cotranslational protein targeting to membrane Source: InterPro

    Keywords - Molecular functioni

    Receptor

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBAPH198804:GHMG-26-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Signal recognition particle receptor FtsYUniRule annotation
    Short name:
    SRP receptorUniRule annotation
    Gene namesi
    Name:ftsYUniRule annotation
    Ordered Locus Names:BUsg_025
    OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
    Taxonomic identifieri198804 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000000416: Chromosome

    Subcellular locationi

    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. intrinsic component of plasma membrane Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cell membrane, Cytoplasm, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 351351Signal recognition particle receptor FtsYPRO_0000101129Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.UniRule annotation

    Protein-protein interaction databases

    STRINGi198804.BUsg025.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8KA77.
    SMRiQ8KA77. Positions 58-351.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding SRP family. FtsY subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0552.
    KOiK03110.
    OMAiSIDEIDW.
    OrthoDBiEOG62K1ZH.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00920. FtsY.
    InterProiIPR003593. AAA+_ATPase.
    IPR027417. P-loop_NTPase.
    IPR013822. Signal_recog_particl_SRP54_hlx.
    IPR004390. SR_rcpt_FtsY.
    IPR000897. SRP54_GTPase_dom.
    [Graphical view]
    PfamiPF00448. SRP54. 1 hit.
    PF02881. SRP54_N. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    SM00962. SRP54. 1 hit.
    SM00963. SRP54_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF47364. SSF47364. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00064. ftsY. 1 hit.
    PROSITEiPS00300. SRP54. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8KA77-1 [UniParc]FASTAAdd to Basket

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    MNFDKKNSFF SWINSKIKKN NKKEKKENIL LKKEKEGIHT IQNIDNKKID    50
    FLFKLKNSLN KTKQFFGDSI SRIFLSKKID DAFFEELEDT MLLSDIGVHT 100
    TDQIISKLIN DATHKELKNP EKVYFLLKEH MYSILNRVEK PLKISNHTPF 150
    VILVVGINGT GKTTTVSKLA KKYKLAGKSV MLAAADTFRA AGIEQLQILG 200
    KRNNIPVISQ SSGSDPASVA FDAVKSAISK KIDVLIIDTA GRLHNKLHLL 250
    EELKKMVRVI KKLNLSAPHE IMLIIDACNG QNTIKQTEMF HKAINLTGLV 300
    ITKLDGTAKG GVIFSLANQF LIPIRYIGIG EKTTDLVVFN SNDFIKSIFV 350
    K 351
    Length:351
    Mass (Da):39,470
    Last modified:October 1, 2002 - v1
    Checksum:i1CA5A59A4B6E7FF3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67596.1.
    RefSeqiNP_660385.1. NC_004061.1.
    WP_011053562.1. NC_004061.1.

    Genome annotation databases

    EnsemblBacteriaiAAM67596; AAM67596; BUsg_025.
    GeneIDi1005841.
    KEGGibas:BUsg025.
    PATRICi21246807. VBIBucAph100086_0025.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67596.1 .
    RefSeqi NP_660385.1. NC_004061.1.
    WP_011053562.1. NC_004061.1.

    3D structure databases

    ProteinModelPortali Q8KA77.
    SMRi Q8KA77. Positions 58-351.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 198804.BUsg025.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM67596 ; AAM67596 ; BUsg_025 .
    GeneIDi 1005841.
    KEGGi bas:BUsg025.
    PATRICi 21246807. VBIBucAph100086_0025.

    Phylogenomic databases

    eggNOGi COG0552.
    KOi K03110.
    OMAi SIDEIDW.
    OrthoDBi EOG62K1ZH.

    Enzyme and pathway databases

    BioCyci BAPH198804:GHMG-26-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00920. FtsY.
    InterProi IPR003593. AAA+_ATPase.
    IPR027417. P-loop_NTPase.
    IPR013822. Signal_recog_particl_SRP54_hlx.
    IPR004390. SR_rcpt_FtsY.
    IPR000897. SRP54_GTPase_dom.
    [Graphical view ]
    Pfami PF00448. SRP54. 1 hit.
    PF02881. SRP54_N. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    SM00962. SRP54. 1 hit.
    SM00963. SRP54_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47364. SSF47364. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00064. ftsY. 1 hit.
    PROSITEi PS00300. SRP54. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Sg.

    Entry informationi

    Entry nameiFTSY_BUCAP
    AccessioniPrimary (citable) accession number: Q8KA77
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 15, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Buchnera aphidicola (subsp. Schizaphis graminum)
      Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3