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Q8KA77

- FTSY_BUCAP

UniProt

Q8KA77 - FTSY_BUCAP

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Protein

Signal recognition particle receptor FtsY

Gene
ftsY, BUsg_025
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi156 – 1638GTP By similarity
Nucleotide bindingi238 – 2425GTP By similarity
Nucleotide bindingi302 – 3054GTP By similarity

GO - Molecular functioni

  1. GTPase activity Source: UniProtKB-HAMAP
  2. GTP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. SRP-dependent cotranslational protein targeting to membrane Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-26-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Signal recognition particle receptor FtsY
Short name:
SRP receptor
Gene namesi
Name:ftsY
Ordered Locus Names:BUsg_025
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. intrinsic component of plasma membrane Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 351351Signal recognition particle receptor FtsYUniRule annotationPRO_0000101129Add
BLAST

Interactioni

Subunit structurei

Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule By similarity.

Protein-protein interaction databases

STRINGi198804.BUsg025.

Structurei

3D structure databases

ProteinModelPortaliQ8KA77.
SMRiQ8KA77. Positions 58-351.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0552.
KOiK03110.
OMAiSIDEIDW.
OrthoDBiEOG62K1ZH.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00920. FtsY.
InterProiIPR003593. AAA+_ATPase.
IPR027417. P-loop_NTPase.
IPR013822. Signal_recog_particl_SRP54_hlx.
IPR004390. SR_rcpt_FtsY.
IPR000897. SRP54_GTPase_dom.
[Graphical view]
PfamiPF00448. SRP54. 1 hit.
PF02881. SRP54_N. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00962. SRP54. 1 hit.
SM00963. SRP54_N. 1 hit.
[Graphical view]
SUPFAMiSSF47364. SSF47364. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00064. ftsY. 1 hit.
PROSITEiPS00300. SRP54. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8KA77-1 [UniParc]FASTAAdd to Basket

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MNFDKKNSFF SWINSKIKKN NKKEKKENIL LKKEKEGIHT IQNIDNKKID    50
FLFKLKNSLN KTKQFFGDSI SRIFLSKKID DAFFEELEDT MLLSDIGVHT 100
TDQIISKLIN DATHKELKNP EKVYFLLKEH MYSILNRVEK PLKISNHTPF 150
VILVVGINGT GKTTTVSKLA KKYKLAGKSV MLAAADTFRA AGIEQLQILG 200
KRNNIPVISQ SSGSDPASVA FDAVKSAISK KIDVLIIDTA GRLHNKLHLL 250
EELKKMVRVI KKLNLSAPHE IMLIIDACNG QNTIKQTEMF HKAINLTGLV 300
ITKLDGTAKG GVIFSLANQF LIPIRYIGIG EKTTDLVVFN SNDFIKSIFV 350
K 351
Length:351
Mass (Da):39,470
Last modified:October 1, 2002 - v1
Checksum:i1CA5A59A4B6E7FF3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE013218 Genomic DNA. Translation: AAM67596.1.
RefSeqiNP_660385.1. NC_004061.1.
WP_011053562.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM67596; AAM67596; BUsg_025.
GeneIDi1005841.
KEGGibas:BUsg025.
PATRICi21246807. VBIBucAph100086_0025.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE013218 Genomic DNA. Translation: AAM67596.1 .
RefSeqi NP_660385.1. NC_004061.1.
WP_011053562.1. NC_004061.1.

3D structure databases

ProteinModelPortali Q8KA77.
SMRi Q8KA77. Positions 58-351.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198804.BUsg025.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM67596 ; AAM67596 ; BUsg_025 .
GeneIDi 1005841.
KEGGi bas:BUsg025.
PATRICi 21246807. VBIBucAph100086_0025.

Phylogenomic databases

eggNOGi COG0552.
KOi K03110.
OMAi SIDEIDW.
OrthoDBi EOG62K1ZH.

Enzyme and pathway databases

BioCyci BAPH198804:GHMG-26-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00920. FtsY.
InterProi IPR003593. AAA+_ATPase.
IPR027417. P-loop_NTPase.
IPR013822. Signal_recog_particl_SRP54_hlx.
IPR004390. SR_rcpt_FtsY.
IPR000897. SRP54_GTPase_dom.
[Graphical view ]
Pfami PF00448. SRP54. 1 hit.
PF02881. SRP54_N. 1 hit.
[Graphical view ]
SMARTi SM00382. AAA. 1 hit.
SM00962. SRP54. 1 hit.
SM00963. SRP54_N. 1 hit.
[Graphical view ]
SUPFAMi SSF47364. SSF47364. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00064. ftsY. 1 hit.
PROSITEi PS00300. SRP54. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiFTSY_BUCAP
AccessioniPrimary (citable) accession number: Q8KA77
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: October 1, 2002
Last modified: September 3, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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