Q8KA69 (DBH_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-binding protein HU

Gene names

Name:	hup
Synonyms:	hupA
Ordered Locus Names:	BUsg_033

Organism

Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]

Taxonomic identifier

198804 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	90 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the bacterial histone-like protein family.

Ontologies

Keywords
Biological process	DNA condensation
Ligand	DNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	chromosome condensation Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 90	90	DNA-binding protein HU		PRO_0000104925

Sequences

	Sequence		Length	Mass (Da)
	Q8KA69 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 8AA4A05ED9E17214	FASTA	90	9,825
	10 20 30 40 50 60 MNKTQLIKII SKQSNLSKIQ IKSTLEKILS AIIESLKKGE SVQIVGFGTF KVNSRASRTG 70 80 90 RNPQTGKEII IPATKVPSFI SGKTLKNAIK

References

[1]	"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sg.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE013218 Genomic DNA. Translation: AAM67604.1.
RefSeq	NP_660393.1. NC_004061.1.
3D structure databases
ProteinModelPortal	Q8KA69.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000000070; EBBUCP00000000070; EBBUCG00000000070.
GeneID	1005849.
GenomeReviews	Gene locus BUsg_033 in contig AE013218_GR.
KEGG	bas:BUsg033.
PATRIC	21246823. VBIBucAph100086_0033.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000007762.
HOGENOM	HBG705085.
OMA	MNSITYE.
ProtClustDB	CLSK315016.
Enzyme and pathway databases
BioCyc	BAPH198804:BUSG033-MONOMER.
Family and domain databases
InterPro	IPR023630. DNA-bd_HU/IHF. IPR000119. Hist_DNA-bd_bac. IPR020816. Histone-like_DNA-bd_CS. IPR010992. IHF-like_DNA-bd. [Graphical view]
Gene3D	G3DSA:4.10.520.10. Hist_DNA_bd_bac. 1 hit.
KO	K05787.
Pfam	PF00216. Bac_DNA_binding. 1 hit. [Graphical view]
PRINTS	PR01727. DNABINDINGHU.
SMART	SM00411. BHL. 1 hit. [Graphical view]
SUPFAM	SSF47729. IHF_like_DNA_bnd. 1 hit.
PROSITE	PS00045. HISTONE_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DBH_BUCAP

Accession

Primary (citable) accession number: Q8KA69

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program