Q8KA67 (RL1_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L1

Gene names

Name:	rplA
Ordered Locus Names:	BUsg_038

Organism

Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]

Taxonomic identifier

198804 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	231 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release By similarity. HAMAP MF_01318_B Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA By similarity. HAMAP MF_01318_B
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L1P family.

Ontologies

Keywords
Biological process	Translation regulation
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Repressor Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	regulation of translation Inferred from electronic annotation. Source: UniProtKB-KW translation Inferred from electronic annotation. Source: InterPro
Cellular component	large ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 231	231	50S ribosomal protein L1 HAMAP MF_01318_B		PRO_0000125631

Sequences

	Sequence		Length	Mass (Da)
	Q8KA67 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 4D234DACF932A3C2	FASTA	231	25,609
	10 20 30 40 50 60 MKKINKRMKK IKNDINFEKL YYIDELIQLL KKSSNVNFNE SIDVAINLGI NPKKSDQNIR 70 80 90 100 110 120 GSTILPHGTG RCVKVAVFTQ GENIKIAKKA GAEFIGMEDL AEQIKKEGIK FHTAIASPDA 130 140 150 160 170 180 MKIVTQLGQI LGPRGLMPNP KLGTVTTNIE EAIKNAKTGQ VCYRNDKNGI IHATIGRINF 190 200 210 220 230 ERNQIKENFN VFLESIKKAK PPQSKGIYIK KVVLSSTMGI GLTLDQSSLS I

References

[1]	"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sg.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE013218 Genomic DNA. Translation: AAM67609.1.
RefSeq	NP_660398.1. NC_004061.1.
3D structure databases
ProteinModelPortal	Q8KA67.
SMR	Q8KA67. Positions 6-227.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000000356; EBBUCP00000000356; EBBUCG00000000356.
GeneID	1005854.
GenomeReviews	Gene locus BUsg_038 in contig AE013218_GR.
KEGG	bas:BUsg038.
PATRIC	21246833. VBIBucAph100086_0038.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000007956.
HOGENOM	HBG297400.
OMA	FEDYIEK.
ProtClustDB	PRK05424.
Enzyme and pathway databases
BioCyc	BAPH198804:BUSG038-MONOMER.
Family and domain databases
HAMAP	MF_01318_B. Ribosomal_L1_B. [Tree]
InterPro	IPR005878. Ribosom_L1_bac-type. IPR002143. Ribosomal_L1. IPR016094. Ribosomal_L1_2-a/b-sand. IPR016095. Ribosomal_L1_3-a/b-sand. IPR023673. Ribosomal_L1_CS. IPR023674. Ribosomal_L1_SF. [Graphical view]
Gene3D	G3DSA:3.30.190.20. Ribosomal_L1_2-a/b-sand. 2 hits. G3DSA:3.40.50.790. Ribosomal_L1_3-a/b-sand. 1 hit.
KO	K02863.
Pfam	PF00687. Ribosomal_L1. 1 hit. [Graphical view]
PIRSF	PIRSF002155. Ribosomal_L1. 1 hit.
SUPFAM	SSF56808. Ribosomal_L1. 1 hit.
TIGRFAMs	TIGR01169. RplA_bact. 1 hit.
PROSITE	PS01199. RIBOSOMAL_L1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL1_BUCAP

Accession

Primary (citable) accession number: Q8KA67

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
Last sequence update:	October 1, 2002
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program