Reviewed,
UniProtKB/Swiss-Prot Q8KA61 (ARGC_BUCAP)
Last modified
June 16, 2009.
Version 51.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: N-acetyl-gamma-glutamyl-phosphate reductase Short name=AGPR EC=1.2.1.38 Alternative name(s): N-acetyl-glutamate semialdehyde dehydrogenase Short name=NAGSA dehydrogenase | ||||
| Gene names |
| ||||
| Organism | Buchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 98794 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera |
Protein attributes
| Sequence length | 334 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH. HAMAP MF_00150 |
| Pathway | Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4. HAMAP MF_00150 |
| Subcellular location | Cytoplasm Probable. |
| Sequence similarities | Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Arginine biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | arginine biosynthetic process Inferred from electronic annotation. Source: HAMAP oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | N-acetyl-gamma-glutamyl-phosphate reductase activity Inferred from electronic annotation. Source: HAMAP NAD or NADH bindingInferred from electronic annotation. Source: InterPro protein dimerization activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 334 | 334 | N-acetyl-gamma-glutamyl-phosphate reductase HAMAP MF_00150 | PRO_0000112392 | |||||
Sites | |||||||||
| Active site | 154 | 1 | By similarity | ||||||
Sequences
| ||||||||||||||||||
References
| [1] | "50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| AE013218 Genomic DNA. Translation: AAM67616.1. | |
| RefSeq | NP_660405.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1005861. |
| GenomeReviews | Gene locus BUsg_045 in contig AE013218_GR. |
| KEGG | bas:BUsg045. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q8KA61. |
| OMA | Q8KA61. VCRIAVH. |
Enzyme and pathway databases | |
| BioCyc | BAPH198804:BUSG045-MON. |
Family and domain databases | |
| HAMAP | MF_00150. [Tree] |
| InterPro | IPR000706. AGPR_act_site. IPR000534. Semialdehyde_DH_NAD-bd. IPR012280. Semialdhyde_DH_C. [Graphical view] |
| Pfam | PF01118. Semialdhyde_dh. 1 hit. PF02774. Semialdhyde_dhC. 1 hit. [Graphical view] |
| ProDom | PD003765. AGPR_act_site. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| TIGRFAMs | TIGR01850. argC. 1 hit. |
| PROSITE | PS01224. ARGC. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ARGC_BUCAP | ||||||||
| Accession | Primary (citable) accession number: Q8KA61 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Buchnera aphidicola (subsp. Schizaphis graminum) Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


