Reviewed,
UniProtKB/Swiss-Prot Q8KA59 (ARLY_BUCAP)
Last modified
February 9, 2010.
Version 58.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Argininosuccinate lyase Short name=ASAL EC=4.3.2.1 Alternative name(s): Arginosuccinase | ||||
| Gene names |
| ||||
| Organism | Buchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 98794 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera |
Protein attributes
| Sequence length | 459 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | 2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. HAMAP MF_00006 |
| Pathway | Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. HAMAP MF_00006 |
| Subcellular location | Cytoplasm Probable HAMAP MF_00006. |
| Sequence similarities | Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Arginine biosynthesis |
| Cellular component | Cytoplasm |
| Molecular function | Lyase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | arginine biosynthetic process via ornithine Inferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | argininosuccinate lyase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 459 | 459 | Argininosuccinate lyase HAMAP MF_00006 | PRO_0000137749 | |||
Sequences
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References
| [1] | "50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE013218 Genomic DNA. Translation: AAM67619.1. |
| RefSeq | NP_660408.1. |
3D structure databases | |
| SMR | Q8KA59. Positions 3-456. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1005864. |
| GenomeReviews | Gene locus BUsg_048 in contig AE013218_GR. |
| KEGG | bas:BUsg048. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG539632. |
| OMA | MAEDLIF. |
Enzyme and pathway databases | |
| BioCyc | BAPH198804:BUSG048-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00006. Arg_succ_lyase. [Tree] |
| InterPro | IPR009049. Argininosuccinate_lyase. IPR003031. D_crystallin. IPR000362. Fumarate_lyase. IPR020557. Fumarate_lyase_CS. IPR008948. L-Aspartase-like. [Graphical view] |
| PANTHER | PTHR11444:SF3. argH. 1 hit. |
| Pfam | PF00206. Lyase_1. 1 hit. [Graphical view] |
| PRINTS | PR00145. ARGSUCLYASE. PR00149. FUMRATELYASE. |
| TIGRFAMs | TIGR00838. argH. 1 hit. |
| PROSITE | PS00163. FUMARATE_LYASES. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ARLY_BUCAP | ||||||||
| Accession | Primary (citable) accession number: Q8KA59 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Buchnera aphidicola (subsp. Schizaphis graminum) Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


