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Q8KA49

- PTHP_BUCAP

UniProt

Q8KA49 - PTHP_BUCAP

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Protein

Phosphocarrier protein HPr

Gene

ptsH

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III) (By similarity).By similarity

Catalytic activityi

Protein HPr N(pi)-phospho-L-histidine + protein EIIA = protein HPr + protein EIIA N(tau)-phospho-L-histidine.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei15 – 151Pros-phosphohistidine intermediatePROSITE-ProRule annotation

GO - Molecular functioni

  1. protein serine/threonine kinase activity Source: UniProtKB-KW

GO - Biological processi

  1. phosphoenolpyruvate-dependent sugar phosphotransferase system Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Biological processi

Phosphotransferase system, Sugar transport, Transport

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-67-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphocarrier protein HPr (EC:2.7.11.-)
Alternative name(s):
Histidine-containing protein
Gene namesi
Name:ptsH
Ordered Locus Names:BUsg_062
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8585Phosphocarrier protein HPrPRO_0000107845Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi198804.BUsg062.

Structurei

3D structure databases

ProteinModelPortaliQ8KA49.
SMRiQ8KA49. Positions 1-85.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 8585HPrPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the HPr family.Curated
Contains 1 HPr domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG1925.
KOiK02784.
OMAiAPHGIHT.
OrthoDBiEOG6XDGX2.

Family and domain databases

Gene3Di3.30.1340.10. 1 hit.
InterProiIPR000032. HPr_prot-like.
IPR001020. PTS_HPr_His_P_site.
IPR002114. PTS_HPr_Ser_P_site.
[Graphical view]
PfamiPF00381. PTS-HPr. 1 hit.
[Graphical view]
PRINTSiPR00107. PHOSPHOCPHPR.
SUPFAMiSSF55594. SSF55594. 1 hit.
TIGRFAMsiTIGR01003. PTS_HPr_family. 1 hit.
PROSITEiPS51350. PTS_HPR_DOM. 1 hit.
PS00369. PTS_HPR_HIS. 1 hit.
PS00589. PTS_HPR_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8KA49-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFQKEIKINA LHGLHTRPAA EFVKEAKNFI SDIHIIYHGK SVNAKSLFKI
60 70 80
QTLGLVKDSV IILSAEGEDE KKAVEHLSKI MTELE
Length:85
Mass (Da):9,571
Last modified:October 1, 2002 - v1
Checksum:i6882A1A6206EAC0E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE013218 Genomic DNA. Translation: AAM67633.1.
RefSeqiNP_660422.1. NC_004061.1.
WP_011053599.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM67633; AAM67633; BUsg_062.
GeneIDi1005878.
KEGGibas:BUsg062.
PATRICi21246889. VBIBucAph100086_0062.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE013218 Genomic DNA. Translation: AAM67633.1 .
RefSeqi NP_660422.1. NC_004061.1.
WP_011053599.1. NC_004061.1.

3D structure databases

ProteinModelPortali Q8KA49.
SMRi Q8KA49. Positions 1-85.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198804.BUsg062.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM67633 ; AAM67633 ; BUsg_062 .
GeneIDi 1005878.
KEGGi bas:BUsg062.
PATRICi 21246889. VBIBucAph100086_0062.

Phylogenomic databases

eggNOGi COG1925.
KOi K02784.
OMAi APHGIHT.
OrthoDBi EOG6XDGX2.

Enzyme and pathway databases

BioCyci BAPH198804:GHMG-67-MONOMER.

Family and domain databases

Gene3Di 3.30.1340.10. 1 hit.
InterProi IPR000032. HPr_prot-like.
IPR001020. PTS_HPr_His_P_site.
IPR002114. PTS_HPr_Ser_P_site.
[Graphical view ]
Pfami PF00381. PTS-HPr. 1 hit.
[Graphical view ]
PRINTSi PR00107. PHOSPHOCPHPR.
SUPFAMi SSF55594. SSF55594. 1 hit.
TIGRFAMsi TIGR01003. PTS_HPr_family. 1 hit.
PROSITEi PS51350. PTS_HPR_DOM. 1 hit.
PS00369. PTS_HPR_HIS. 1 hit.
PS00589. PTS_HPR_SER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiPTHP_BUCAP
AccessioniPrimary (citable) accession number: Q8KA49
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: October 29, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3