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Q8KA49

- PTHP_BUCAP

UniProt

Q8KA49 - PTHP_BUCAP

Protein

Phosphocarrier protein HPr

Gene

ptsH

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III) By similarity.By similarity

    Catalytic activityi

    Protein HPr N(pi)-phospho-L-histidine + protein EIIA = protein HPr + protein EIIA N(tau)-phospho-L-histidine.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei15 – 151Pros-phosphohistidine intermediatePROSITE-ProRule annotation

    GO - Molecular functioni

    1. protein serine/threonine kinase activity Source: UniProtKB-KW

    GO - Biological processi

    1. phosphoenolpyruvate-dependent sugar phosphotransferase system Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Biological processi

    Phosphotransferase system, Sugar transport, Transport

    Enzyme and pathway databases

    BioCyciBAPH198804:GHMG-67-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphocarrier protein HPr (EC:2.7.11.-)
    Alternative name(s):
    Histidine-containing protein
    Gene namesi
    Name:ptsH
    Ordered Locus Names:BUsg_062
    OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
    Taxonomic identifieri198804 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000000416: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 8585Phosphocarrier protein HPrPRO_0000107845Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi198804.BUsg062.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8KA49.
    SMRiQ8KA49. Positions 1-85.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 8585HPrPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the HPr family.Curated
    Contains 1 HPr domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG1925.
    KOiK02784.
    OMAiAPHGIHT.
    OrthoDBiEOG6XDGX2.

    Family and domain databases

    Gene3Di3.30.1340.10. 1 hit.
    InterProiIPR000032. HPr_prot-like.
    IPR001020. PTS_HPr_His_P_site.
    IPR002114. PTS_HPr_Ser_P_site.
    [Graphical view]
    PfamiPF00381. PTS-HPr. 1 hit.
    [Graphical view]
    PRINTSiPR00107. PHOSPHOCPHPR.
    SUPFAMiSSF55594. SSF55594. 1 hit.
    TIGRFAMsiTIGR01003. PTS_HPr_family. 1 hit.
    PROSITEiPS51350. PTS_HPR_DOM. 1 hit.
    PS00369. PTS_HPR_HIS. 1 hit.
    PS00589. PTS_HPR_SER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8KA49-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFQKEIKINA LHGLHTRPAA EFVKEAKNFI SDIHIIYHGK SVNAKSLFKI   50
    QTLGLVKDSV IILSAEGEDE KKAVEHLSKI MTELE 85
    Length:85
    Mass (Da):9,571
    Last modified:October 1, 2002 - v1
    Checksum:i6882A1A6206EAC0E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67633.1.
    RefSeqiNP_660422.1. NC_004061.1.
    WP_011053599.1. NC_004061.1.

    Genome annotation databases

    EnsemblBacteriaiAAM67633; AAM67633; BUsg_062.
    GeneIDi1005878.
    KEGGibas:BUsg062.
    PATRICi21246889. VBIBucAph100086_0062.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67633.1 .
    RefSeqi NP_660422.1. NC_004061.1.
    WP_011053599.1. NC_004061.1.

    3D structure databases

    ProteinModelPortali Q8KA49.
    SMRi Q8KA49. Positions 1-85.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 198804.BUsg062.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM67633 ; AAM67633 ; BUsg_062 .
    GeneIDi 1005878.
    KEGGi bas:BUsg062.
    PATRICi 21246889. VBIBucAph100086_0062.

    Phylogenomic databases

    eggNOGi COG1925.
    KOi K02784.
    OMAi APHGIHT.
    OrthoDBi EOG6XDGX2.

    Enzyme and pathway databases

    BioCyci BAPH198804:GHMG-67-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1340.10. 1 hit.
    InterProi IPR000032. HPr_prot-like.
    IPR001020. PTS_HPr_His_P_site.
    IPR002114. PTS_HPr_Ser_P_site.
    [Graphical view ]
    Pfami PF00381. PTS-HPr. 1 hit.
    [Graphical view ]
    PRINTSi PR00107. PHOSPHOCPHPR.
    SUPFAMi SSF55594. SSF55594. 1 hit.
    TIGRFAMsi TIGR01003. PTS_HPr_family. 1 hit.
    PROSITEi PS51350. PTS_HPR_DOM. 1 hit.
    PS00369. PTS_HPR_HIS. 1 hit.
    PS00589. PTS_HPR_SER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Sg.

    Entry informationi

    Entry nameiPTHP_BUCAP
    AccessioniPrimary (citable) accession number: Q8KA49
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Buchnera aphidicola (subsp. Schizaphis graminum)
      Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3