Reviewed, UniProtKB/Swiss-Prot Q8KA06 (SYGA_BUCAP)

Names and origin

Protein names

Recommended name:
    Glycyl-tRNA synthetase alpha subunit
    EC=6.1.1.14
Alternative name(s):
    Glycine--tRNA ligase alpha subunit
      Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	BUsg_128

Organism

Buchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP]

Taxonomic identifier

98794 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	292 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00254
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glycine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 292	292	Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254		PRO_0000072831

Sequences

	Sequence		Length	Mass (Da)
	Q8KA06-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 180B7BB3CED6E37B	FASTA	292	34,557
	10 20 30 40 50 60 MENNHNNFSN LITILQEYWT EQECAIFQPL DLPIGAGTFH NTTFFGTIGP EPIRAAYIQS 70 80 90 100 110 120 CRRPTDGRYG KNPNRLQHYY QFQVIIKPPL KNIQNIYLKS LNLLKISEKR NDIRFVEDNW 130 140 150 160 170 180 ENPTLGAWGI GWEVWLNGME ITQFTYFQQV GGLECNPVTV EITYGLERIA MHMQNQSNVY 190 200 210 220 230 240 DLIWSENKFK KITYGDIFQQ NEIEQSKYNF EYSDINLLFE YFQKYIFEAK KLIELKKPLL 250 260 270 280 290 LVSYEKILQA SHVFNLLDAR KAISSSERQN YILKIRKLAK KIAQEYLYSR KK

References

[1]

"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE013218 Genomic DNA. Translation: AAM67696.1.
RefSeq	NP_660485.1.
3D structure databases
HSSP	HSSP built from PDB template 1J5W based on UniProtKB Q9WY59.
ModBase	Search...
Genome annotation databases
GeneID	1005945.
GenomeReviews	Gene locus BUsg_128 in contig AE013218_GR.
KEGG	bas:BUsg128.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8KA06.
OMA	CRRPTDG.
Enzyme and pathway databases
BioCyc	BAPH198804:BUSG128-MON.
Family and domain databases
HAMAP	MF_00254. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
ProDom	PD006985. tRNA_synt_2e. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_BUCAP

Accession

Primary (citable) accession number: Q8KA06

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
Last sequence update:	October 1, 2002
Last modified:	November 3, 2009
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)