Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8KA01

- SURA_BUCAP

UniProt

Q8KA01 - SURA_BUCAP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Chaperone SurA

Gene

surA

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation By similarity.By similarity

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).

GO - Molecular functioni

  1. peptide binding Source: InterPro
  2. peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. biofilm formation Source: InterPro
  2. chaperone mediated protein folding requiring cofactor Source: InterPro
  3. Gram-negative-bacterium-type cell outer membrane assembly Source: InterPro
  4. maintenance of stationary phase Source: InterPro
  5. protein stabilization Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Chaperone, Isomerase, Rotamase

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-143-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone SurA
Alternative name(s):
Peptidyl-prolyl cis-trans isomerase SurA (EC:5.2.1.8)
Short name:
PPIase SurA
Rotamase SurA
Gene namesi
Name:surA
Ordered Locus Names:BUsg_133
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416: Chromosome

Subcellular locationi

Periplasm By similarity
Note: Is capable of associating with the outer membrane.By similarity

GO - Cellular componenti

  1. outer membrane-bounded periplasmic space Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence AnalysisAdd
BLAST
Chaini22 – 432411Chaperone SurAPRO_0000025541Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi198804.BUsg133.

Structurei

3D structure databases

ProteinModelPortaliQ8KA01.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini175 – 276102PpiC 1Add
BLAST
Domaini286 – 386101PpiC 2Add
BLAST

Domaini

The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition By similarity.By similarity

Sequence similaritiesi

Contains 2 PpiC domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiCOG0760.
KOiK03771.
OMAiLGKMQLS.
OrthoDBiEOG6M9DS4.

Family and domain databases

HAMAPiMF_01183. Chaperone_SurA.
InterProiIPR000297. PPIase_PpiC.
IPR023034. PPIase_SurA.
IPR015391. SurA_N.
IPR027304. Trigger_fact/SurA_dom.
[Graphical view]
PfamiPF00639. Rotamase. 1 hit.
PF09312. SurA_N. 1 hit.
[Graphical view]
SUPFAMiSSF109998. SSF109998. 1 hit.
PROSITEiPS50198. PPIC_PPIASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8KA01-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKVYFFLILY VFLSFFSITY SKELEIDKII AIVNNQIILN SDVNQVLFSL
60 70 80 90 100
KEEDQRVKIP LKINFLRNKI IKKLITETLI LEEAKKFNIV VTDDQVNNVL
110 120 130 140 150
SKYALKKNIT IEELKRNILM NNTNTSFSYN DYFNKIKNSL KVKIIQDYVL
160 170 180 190 200
HNRVHISEKE VDLFLNKLIN TQNELKKIDI NCIFLPFIKE KNKIFIKNTK
210 220 230 240 250
ILADHFAKKI KKDASFNYYY EYFKKNNNIF LSKEIRSKSL KYLKKIFLNK
260 270 280 290 300
LKIIKKNQIL GPILGLKGFY ILKINKIENE NKENLTTEFH IQHCLIRPSV
310 320 330 340 350
ILDDKQAKNS IYYIYNNIKN KKYSFDYAVQ KLSHDVYSSH KKGDLGWIST
360 370 380 390 400
DFFSNDFRNF LTDLRKNEIS KPIKSNFGWH IIKLLDIRQV DKSNRIDKNL
410 420 430
VYRFLLEKKI KKERYNWIRQ LKKSSYIKIF KN
Length:432
Mass (Da):51,748
Last modified:October 1, 2002 - v1
Checksum:i698284DB452257ED
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE013218 Genomic DNA. Translation: AAM67701.1.
RefSeqiNP_660490.1. NC_004061.1.
WP_011053668.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM67701; AAM67701; BUsg_133.
GeneIDi1005950.
KEGGibas:BUsg133.
PATRICi21247047. VBIBucAph100086_0137.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE013218 Genomic DNA. Translation: AAM67701.1 .
RefSeqi NP_660490.1. NC_004061.1.
WP_011053668.1. NC_004061.1.

3D structure databases

ProteinModelPortali Q8KA01.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198804.BUsg133.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM67701 ; AAM67701 ; BUsg_133 .
GeneIDi 1005950.
KEGGi bas:BUsg133.
PATRICi 21247047. VBIBucAph100086_0137.

Phylogenomic databases

eggNOGi COG0760.
KOi K03771.
OMAi LGKMQLS.
OrthoDBi EOG6M9DS4.

Enzyme and pathway databases

BioCyci BAPH198804:GHMG-143-MONOMER.

Family and domain databases

HAMAPi MF_01183. Chaperone_SurA.
InterProi IPR000297. PPIase_PpiC.
IPR023034. PPIase_SurA.
IPR015391. SurA_N.
IPR027304. Trigger_fact/SurA_dom.
[Graphical view ]
Pfami PF00639. Rotamase. 1 hit.
PF09312. SurA_N. 1 hit.
[Graphical view ]
SUPFAMi SSF109998. SSF109998. 1 hit.
PROSITEi PS50198. PPIC_PPIASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiSURA_BUCAP
AccessioniPrimary (citable) accession number: Q8KA01
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: October 1, 2002
Last modified: October 1, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3