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Q8K9X0 (RF1_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Peptide chain release factor 1

Short name=RF-1
Gene names
Name:prfA
Ordered Locus Names:BUsg_165
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length361 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA By similarity. HAMAP-Rule MF_00093

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00093.

Post-translational modification

Methylated by PrmC. Methylation increases the termination efficiency of RF1 By similarity. HAMAP-Rule MF_00093

Sequence similarities

Belongs to the prokaryotic/mitochondrial release factor family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   PTMMethylation
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation release factor activity, codon specific

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 361361Peptide chain release factor 1 HAMAP-Rule MF_00093
PRO_0000177647

Amino acid modifications

Modified residue2351N5-methylglutamine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8K9X0 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 0C69E163BA05D21D

FASTA36141,459
        10         20         30         40         50         60 
MNSSIFNKLK SLRNRYEEIE IMLSQKDTIS NQEKFKNLSK EYLQISEIVK NFIKWEKLET 

        70         80         90        100        110        120 
DIKNINLLFN DVEMHDIAQE ELFIVKKQKK KLEEKIKILL LPVDPNDQHS CFIEIRAATG 

       130        140        150        160        170        180 
GDESSIFAGE LFRMYTRYAE NYMWKTEIMS SSENERGGFK EIIAKVTGKG ACGRLKFESG 

       190        200        210        220        230        240 
GHRVQRVPET ESQGRIHTST CTVAIMPVRP KTKKEEIKVS DLKIDTFRSS GAGGQHVNTT 

       250        260        270        280        290        300 
DSAIRITHIP SGNVVECQDE RSQHKNKAKA LSILSARVYA DKLAKSQKEN SSMRRILLGT 

       310        320        330        340        350        360 
GERSDRNRTY NFAQNRITDH RINLTIYKLN EVLQGKLDLL IDPIMQEYQA DMLSSLSEFK 


L 

« Hide

References

[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE013218 Genomic DNA. Translation: AAM67732.1.
RefSeqNP_660521.1. NC_004061.1.

3D structure databases

ProteinModelPortalQ8K9X0.
SMRQ8K9X0. Positions 8-353.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING198804.BUsg165.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM67732; AAM67732; BUsg_165.
GeneID1005362.
KEGGbas:BUsg165.
PATRIC21247111. VBIBucAph100086_0169.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0216.
KOK02835.
OMAYGQLKFE.
OrthoDBEOG6TN48J.

Enzyme and pathway databases

BioCycBAPH198804:GHMG-174-MONOMER.

Family and domain databases

Gene3D3.30.160.20. 1 hit.
HAMAPMF_00093. Rel_fac_1.
InterProIPR014720. dsRNA-bd_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004373. PrfA.
[Graphical view]
PfamPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsTIGR00019. prfA. 1 hit.
PROSITEPS00745. RF_PROK_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRF1_BUCAP
AccessionPrimary (citable) accession number: Q8K9X0
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: May 14, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names