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Protein

Peptide chain release factor 1

Gene

prfA

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.UniRule annotation

GO - Molecular functioni

Keywordsi

Biological processProtein biosynthesis

Enzyme and pathway databases

BioCyciBAPH198804:G1FZU-178-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide chain release factor 1UniRule annotation
Short name:
RF-1UniRule annotation
Gene namesi
Name:prfAUniRule annotation
Ordered Locus Names:BUsg_165
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera
Proteomesi
  • UP000000416 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001776471 – 361Peptide chain release factor 1Add BLAST361

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei235N5-methylglutamineUniRule annotation1

Post-translational modificationi

Methylated by PrmC. Methylation increases the termination efficiency of RF1.UniRule annotation

Keywords - PTMi

Methylation

Proteomic databases

PRIDEiQ8K9X0

Interactioni

Protein-protein interaction databases

STRINGi198804.BUsg165

Structurei

3D structure databases

ProteinModelPortaliQ8K9X0
SMRiQ8K9X0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the prokaryotic/mitochondrial release factor family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C8K Bacteria
COG0216 LUCA
KOiK02835
OMAiWKVEIVS
OrthoDBiPOG091H021P

Family and domain databases

HAMAPiMF_00093 Rel_fac_1, 1 hit
InterProiView protein in InterPro
IPR005139 PCRF
IPR000352 Pep_chain_release_fac_I_II
IPR004373 PrfA
PfamiView protein in Pfam
PF03462 PCRF, 1 hit
PF00472 RF-1, 1 hit
SMARTiView protein in SMART
SM00937 PCRF, 1 hit
TIGRFAMsiTIGR00019 prfA, 1 hit
PROSITEiView protein in PROSITE
PS00745 RF_PROK_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q8K9X0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSSIFNKLK SLRNRYEEIE IMLSQKDTIS NQEKFKNLSK EYLQISEIVK
60 70 80 90 100
NFIKWEKLET DIKNINLLFN DVEMHDIAQE ELFIVKKQKK KLEEKIKILL
110 120 130 140 150
LPVDPNDQHS CFIEIRAATG GDESSIFAGE LFRMYTRYAE NYMWKTEIMS
160 170 180 190 200
SSENERGGFK EIIAKVTGKG ACGRLKFESG GHRVQRVPET ESQGRIHTST
210 220 230 240 250
CTVAIMPVRP KTKKEEIKVS DLKIDTFRSS GAGGQHVNTT DSAIRITHIP
260 270 280 290 300
SGNVVECQDE RSQHKNKAKA LSILSARVYA DKLAKSQKEN SSMRRILLGT
310 320 330 340 350
GERSDRNRTY NFAQNRITDH RINLTIYKLN EVLQGKLDLL IDPIMQEYQA
360
DMLSSLSEFK L
Length:361
Mass (Da):41,459
Last modified:October 1, 2002 - v1
Checksum:i0C69E163BA05D21D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA Translation: AAM67732.1
RefSeqiWP_011053699.1, NC_004061.1

Genome annotation databases

EnsemblBacteriaiAAM67732; AAM67732; BUsg_165
KEGGibas:BUsg_165

Similar proteinsi

Entry informationi

Entry nameiRF1_BUCAP
AccessioniPrimary (citable) accession number: Q8K9X0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: May 23, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health