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Q8K9W5 (PTA_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate acetyltransferase

EC=2.3.1.8
Alternative name(s):
Phosphotransacetylase
Gene names
Name:pta
Ordered Locus Names:BUsg_170
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length709 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in acetate metabolism By similarity.

Catalytic activity

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.

Subunit structure

Homohexamer By similarity.

Subcellular location

Cytoplasm Potential.

Domain

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.

Sequence similarities

In the N-terminal section; belongs to the CobB/CobQ family.

In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphate acetyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 709709Phosphate acetyltransferase
PRO_0000179123

Regions

Region389 – 709321Phosphate acetyltransferase

Sequences

Sequence LengthMass (Da)Tools
Q8K9W5 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: DF21DF13C0FC3FB7

FASTA70981,236
        10         20         30         40         50         60 
MSRIIMLIPL NKKVSLTTIS LSILYFFNKK EQKNCFKSFS YLPLIKSDNI NFIRAYFSKK 

        70         80         90        100        110        120 
INVLDDINFF KKNFNSDEYS YLLDKIIKEC FNKKKINEFI LIKGISRKEH DDADQINFDI 

       130        140        150        160        170        180 
AQNIDAEVIF IDNLKDFSLG CFKRKERKIN VFLQQKKYKN FLGLIFSDIN SPFIFNKMKY 

       190        200        210        220        230        240 
NFFDKLIILK NTKKNTCIHA IKKNIFFNSF FRVIAFIPWN KKLVKSSVIN IFKFLNATLV 

       250        260        270        280        290        300 
NTISIKDAFI KNITIFDEDS SVILKKSYAN TLVLISSSRM ETFFKTLYLV CKSKKIGAIL 

       310        320        330        340        350        360 
LTGVLKLSEN SIKLLKFLTN QGVPVFFIKE NTVETLSQLQ KFNFNINVQN KYFINKLLEY 

       370        380        390        400        410        420 
TSSFFNKNHL ISLKKKTTNF YKKTYSPKEF CYRLKILSKS KHKRIILPES YEPRILKAAS 

       430        440        450        460        470        480 
ICHRLGIAEC ILLGDPKKIY NIANENKIDL NKNIEIKDPI LIRDQYVPRL LEIRKNKKID 

       490        500        510        520        530        540 
EIFARKQLKD NVILATLILE SGKVDGLVSG TINTTANTIR PALQIIKTDP IYSLVSSIFF 

       550        560        570        580        590        600 
ILLPNEVLIY GDCAINIEPN SKELAEIAIQ SANSAKMFGI EPRIAMLSYS TGFSGTGWQV 

       610        620        630        640        650        660 
EKIRDATSIV KSKRPDLLID GPIQYDAAIS KEVAKLKIPY SSILGSANIF IFPDLNSGNI 

       670        680        690        700 
TYKAVQRSAD LICIGPMLQG LKKPVNDLSR GASVEDIVYT IALTSIQSL 

« Hide

References

[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE013218 Genomic DNA. Translation: AAM67737.1.
RefSeqNP_660526.1. NC_004061.1.

3D structure databases

ProteinModelPortalQ8K9W5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING198804.BUsg170.

Proteomic databases

PRIDEQ8K9W5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM67737; AAM67737; BUsg_170.
GeneID1005367.
KEGGbas:BUsg170.
PATRIC21247121. VBIBucAph100086_0174.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0280.
KOK13788.
OMAYSIANDN.
OrthoDBEOG6BKJ5W.

Enzyme and pathway databases

BioCycBAPH198804:GHMG-179-MONOMER.
UniPathwayUPA00340; UER00459.

Family and domain databases

Gene3D3.40.1390.20. 1 hit.
InterProIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr_N_like.
[Graphical view]
PfamPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMSSF75138. SSF75138. 1 hit.
TIGRFAMsTIGR00651. pta. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTA_BUCAP
AccessionPrimary (citable) accession number: Q8K9W5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: October 1, 2002
Last modified: June 11, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names