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Q8K9V1

- THRC_BUCAP

UniProt

Q8K9V1 - THRC_BUCAP

Protein

Threonine synthase

Gene

thrC

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.By similarity

    Catalytic activityi

    O-phospho-L-homoserine + H2O = L-threonine + phosphate.

    Cofactori

    Pyridoxal phosphate.By similarity

    Pathwayi

    GO - Molecular functioni

    1. pyridoxal phosphate binding Source: InterPro
    2. threonine synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. threonine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Amino-acid biosynthesis, Threonine biosynthesis

    Keywords - Ligandi

    Pyridoxal phosphate

    Enzyme and pathway databases

    BioCyciBAPH198804:GHMG-196-MONOMER.
    UniPathwayiUPA00050; UER00065.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Threonine synthase (EC:4.2.3.1)
    Short name:
    TS
    Gene namesi
    Name:thrC
    Ordered Locus Names:BUsg_186
    OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
    Taxonomic identifieri198804 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000000416: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 429429Threonine synthasePRO_0000185628Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei108 – 1081N6-(pyridoxal phosphate)lysineBy similarity

    Proteomic databases

    PRIDEiQ8K9V1.

    Interactioni

    Protein-protein interaction databases

    STRINGi198804.BUsg186.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8K9V1.
    SMRiQ8K9V1. Positions 1-427.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the threonine synthase family.Curated

    Phylogenomic databases

    eggNOGiCOG0498.
    KOiK01733.
    OMAiCAINAVE.
    OrthoDBiEOG65BDJX.

    Family and domain databases

    Gene3Di3.90.1380.10. 1 hit.
    InterProiIPR000634. Ser/Thr_deHydtase_PyrdxlP-BS.
    IPR029144. Thr_synth_N.
    IPR004450. Thr_synthase_like.
    IPR001926. Trp_syn_b_sub_like_PLP_eny_SF.
    [Graphical view]
    PfamiPF00291. PALP. 1 hit.
    PF14821. Thr_synth_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF53686. SSF53686. 1 hit.
    TIGRFAMsiTIGR00260. thrC. 1 hit.
    PROSITEiPS00165. DEHYDRATASE_SER_THR. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8K9V1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLYNLKNHN EQVNFETAVK LGLGQKQGLF FPVKLPIMTP VELSKILKMD    50
    FITRSTEILS KFISSEISKE VLHEHVKKAF SFSKPLKICI NKNISCFELF 100
    HGPTLAFKDF GARFMAQMIL CLNKKNESFT ILTATSGDTG AAVAHAFYGM 150
    KNIRVIILYP KGKITLLQEQ LFCTLGKNIK TISINGSFDD CQKLVKKAFD 200
    DKKLKESIGL NSANSINISR LLAQICYYFE AFSLISEEKR KNLVIAVPCG 250
    NFGNLTAGLL AKSLGLPIQS FIACTNSNDT VPRFLNSGKW NPKKTVSTIS 300
    NAMDISCPNN WPRIEELFRR KKWDLKELRF GSVSDNVTKE TLKELFRMGY 350
    VSEPHAAIAY RLLHDQLKKE EFGLFLGTAH PSKFKDTVEK ILENSISLPK 400
    ELKNRNNLPL LSHNINPDFN KLKEFLLEK 429
    Length:429
    Mass (Da):48,585
    Last modified:October 1, 2002 - v1
    Checksum:i36AAB233D3C47BE6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67751.1.
    RefSeqiNP_660540.1. NC_004061.1.
    WP_011053718.1. NC_004061.1.

    Genome annotation databases

    EnsemblBacteriaiAAM67751; AAM67751; BUsg_186.
    GeneIDi1005383.
    KEGGibas:BUsg186.
    PATRICi21247155. VBIBucAph100086_0191.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67751.1 .
    RefSeqi NP_660540.1. NC_004061.1.
    WP_011053718.1. NC_004061.1.

    3D structure databases

    ProteinModelPortali Q8K9V1.
    SMRi Q8K9V1. Positions 1-427.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 198804.BUsg186.

    Proteomic databases

    PRIDEi Q8K9V1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM67751 ; AAM67751 ; BUsg_186 .
    GeneIDi 1005383.
    KEGGi bas:BUsg186.
    PATRICi 21247155. VBIBucAph100086_0191.

    Phylogenomic databases

    eggNOGi COG0498.
    KOi K01733.
    OMAi CAINAVE.
    OrthoDBi EOG65BDJX.

    Enzyme and pathway databases

    UniPathwayi UPA00050 ; UER00065 .
    BioCyci BAPH198804:GHMG-196-MONOMER.

    Family and domain databases

    Gene3Di 3.90.1380.10. 1 hit.
    InterProi IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS.
    IPR029144. Thr_synth_N.
    IPR004450. Thr_synthase_like.
    IPR001926. Trp_syn_b_sub_like_PLP_eny_SF.
    [Graphical view ]
    Pfami PF00291. PALP. 1 hit.
    PF14821. Thr_synth_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53686. SSF53686. 1 hit.
    TIGRFAMsi TIGR00260. thrC. 1 hit.
    PROSITEi PS00165. DEHYDRATASE_SER_THR. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Sg.

    Entry informationi

    Entry nameiTHRC_BUCAP
    AccessioniPrimary (citable) accession number: Q8K9V1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 15, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Buchnera aphidicola (subsp. Schizaphis graminum)
      Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3