Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8K9U3

- SECA_BUCAP

UniProt

Q8K9U3 - SECA_BUCAP

Protein

Protein translocase subunit SecA

Gene

secA

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.UniRule annotation

    Cofactori

    May bind 1 zinc ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi859 – 8591ZincUniRule annotation
    Metal bindingi861 – 8611ZincUniRule annotation
    Metal bindingi870 – 8701ZincUniRule annotation
    Metal bindingi871 – 8711ZincUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi102 – 1098ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. intracellular protein transmembrane transport Source: UniProtKB-HAMAP
    2. protein import Source: InterPro
    3. protein targeting Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Protein transport, Translocation, Transport

    Keywords - Ligandi

    ATP-binding, Metal-binding, Nucleotide-binding, Zinc

    Enzyme and pathway databases

    BioCyciBAPH198804:GHMG-205-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein translocase subunit SecAUniRule annotation
    Gene namesi
    Name:secAUniRule annotation
    Ordered Locus Names:BUsg_195
    OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
    Taxonomic identifieri198804 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000000416: Chromosome

    Subcellular locationi

    Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation. Cytoplasm UniRule annotation
    Note: Distribution is 50-50.UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Cytoplasm, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 874874Protein translocase subunit SecAPRO_0000109579Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.UniRule annotation

    Protein-protein interaction databases

    STRINGi198804.BUsg195.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8K9U3.
    SMRiQ8K9U3. Positions 9-829.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the SecA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0653.
    KOiK03070.
    OMAiEAYEFQQ.
    OrthoDBiEOG654P48.

    Family and domain databases

    Gene3Di1.10.3060.10. 1 hit.
    3.40.50.300. 3 hits.
    3.90.1440.10. 1 hit.
    HAMAPiMF_01382. SecA.
    InterProiIPR027417. P-loop_NTPase.
    IPR004027. SEC_C_motif.
    IPR000185. SecA.
    IPR020937. SecA_CS.
    IPR011115. SecA_DEAD.
    IPR014018. SecA_motor_DEAD.
    IPR011130. SecA_preprotein_X-link_dom.
    IPR011116. SecA_Wing/Scaffold.
    [Graphical view]
    PfamiPF02810. SEC-C. 1 hit.
    PF07517. SecA_DEAD. 1 hit.
    PF01043. SecA_PP_bind. 1 hit.
    PF07516. SecA_SW. 1 hit.
    [Graphical view]
    PRINTSiPR00906. SECA.
    SMARTiSM00957. SecA_DEAD. 1 hit.
    SM00958. SecA_PP_bind. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 3 hits.
    SSF81767. SSF81767. 1 hit.
    SSF81886. SSF81886. 1 hit.
    TIGRFAMsiTIGR00963. secA. 1 hit.
    PROSITEiPS01312. SECA. 1 hit.
    PS51196. SECA_MOTOR_DEAD. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8K9U3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFIKFLHKIF SNRNDRILKK FKKIVSSINQ LEEKFKKLSD KKLQENTGIF    50
    RLRLKKGECL DDLLPESFAT VREASRRVFN MRHFDVQILG GIVLNKQCIA 100
    EMRTGEGKTL TSTLPAYLNA LTGRGVHIVT MNDYLAERDA KNNTPLFEFL 150
    GLTVGLNLPE MSFIDKKKAY LCDITYGTNN EYGFDYLRDN MIFSAEERVQ 200
    RELNYALIDE VDSILIDEAR TPLIISGPSE DSSFLYKEIN KLVPSLICQK 250
    KEDSDKFHGN GHFSIDEKSK QIYLTERGLV EVEKILLDRK LMKKEESLYS 300
    SNNIILMHHV ISALRAHNLF TRNIDYLVKD NNIIIVDEHT GRTMPGRRWS 350
    DGLHQAIEAK ENVTVRNENQ TLASITFQNY FRLYKKIAGM TGTAATESFE 400
    FSSIYNLDTV IIPPNKPMIR KDLSDLVYMT EEEKINAILK DIKNCIKKNQ 450
    PVLVGTISIE KSEMISKKLK ILNIKHNVLN AKFHAREAEI IAQAGKPKSV 500
    TIATNMAGRG TDIVLGGSLE SQLEKNMYLD KIETIKRNWK KQHDLVVLSG 550
    GLHIIGTERH ESRRIDNQLR GRSGRQGDSG SSRFYLSMED SLMRIFASDK 600
    IISMMRKLGL SLNEAIEHPW VTKAIENAQK KVENRNFDIR KQLLEYDDVC 650
    NEQRRVIYAQ RNKLIDSENI QQNIYDILKD VLHSIIKTHL NFDFPKNTRN 700
    ILDLENKLSI EFNLNISIKD WLKKDHDIKK ENIIKKIIDI AKKNYLNKEI 750
    QIGFHNIRMI EKSIMLKTLD SLWKEHLSAM DYLRQGIHLR GYAQKDPKQE 800
    YKRESFNMFS NMLELLKYEV ISFLSKLDIS YIKSNLHLNM NNNSSIVNND 850
    IKMGRNTPCF CKSGKKYKYC HGSL 874
    Length:874
    Mass (Da):101,164
    Last modified:October 1, 2002 - v1
    Checksum:iBC49815F42051791
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67759.1.
    RefSeqiNP_660548.1. NC_004061.1.
    WP_011053726.1. NC_004061.1.

    Genome annotation databases

    EnsemblBacteriaiAAM67759; AAM67759; BUsg_195.
    GeneIDi1005392.
    KEGGibas:BUsg195.
    PATRICi21247177. VBIBucAph100086_0202.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67759.1 .
    RefSeqi NP_660548.1. NC_004061.1.
    WP_011053726.1. NC_004061.1.

    3D structure databases

    ProteinModelPortali Q8K9U3.
    SMRi Q8K9U3. Positions 9-829.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 198804.BUsg195.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM67759 ; AAM67759 ; BUsg_195 .
    GeneIDi 1005392.
    KEGGi bas:BUsg195.
    PATRICi 21247177. VBIBucAph100086_0202.

    Phylogenomic databases

    eggNOGi COG0653.
    KOi K03070.
    OMAi EAYEFQQ.
    OrthoDBi EOG654P48.

    Enzyme and pathway databases

    BioCyci BAPH198804:GHMG-205-MONOMER.

    Family and domain databases

    Gene3Di 1.10.3060.10. 1 hit.
    3.40.50.300. 3 hits.
    3.90.1440.10. 1 hit.
    HAMAPi MF_01382. SecA.
    InterProi IPR027417. P-loop_NTPase.
    IPR004027. SEC_C_motif.
    IPR000185. SecA.
    IPR020937. SecA_CS.
    IPR011115. SecA_DEAD.
    IPR014018. SecA_motor_DEAD.
    IPR011130. SecA_preprotein_X-link_dom.
    IPR011116. SecA_Wing/Scaffold.
    [Graphical view ]
    Pfami PF02810. SEC-C. 1 hit.
    PF07517. SecA_DEAD. 1 hit.
    PF01043. SecA_PP_bind. 1 hit.
    PF07516. SecA_SW. 1 hit.
    [Graphical view ]
    PRINTSi PR00906. SECA.
    SMARTi SM00957. SecA_DEAD. 1 hit.
    SM00958. SecA_PP_bind. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 3 hits.
    SSF81767. SSF81767. 1 hit.
    SSF81886. SSF81886. 1 hit.
    TIGRFAMsi TIGR00963. secA. 1 hit.
    PROSITEi PS01312. SECA. 1 hit.
    PS51196. SECA_MOTOR_DEAD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Sg.

    Entry informationi

    Entry nameiSECA_BUCAP
    AccessioniPrimary (citable) accession number: Q8K9U3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Buchnera aphidicola (subsp. Schizaphis graminum)
      Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3