ID   COAE_BUCAP              Reviewed;         210 AA.
AC   Q8K9U1;
DT   08-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   16-JUN-2009, entry version 44.
DE   RecName: Full=Dephospho-CoA kinase;
DE            EC=2.7.1.24;
DE   AltName: Full=Dephosphocoenzyme A kinase;
GN   Name=coaE; OrderedLocusNames=BUsg_197;
OS   Buchnera aphidicola subsp. Schizaphis graminum.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Buchnera.
OX   NCBI_TaxID=98794;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   MEDLINE=22084549; PubMed=12089438; DOI=10.1126/science.1071278;
RA   Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S.,
RA   Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
RT   "50 million years of genomic stasis in endosymbiotic bacteria.";
RL   Science 296:2376-2379(2002).
CC   -!- FUNCTION: Catalyzes the phosphorylation of the 3'-hydroxyl group
CC       of dephosphocoenzyme A to form coenzyme A (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + 3'-dephospho-CoA = ADP + CoA.
CC   -!- PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme
CC       A from pantothenate: step 5/5.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the coaE family.
CC   -!- SIMILARITY: Contains 1 DPCK (dephospho-CoA kinase) domain.
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DR   EMBL; AE013218; AAM67761.1; -; Genomic_DNA.
DR   RefSeq; NP_660550.1; -.
DR   HSSP; P36679; 1N3B.
DR   GeneID; 1005394; -.
DR   GenomeReviews; AE013218_GR; BUsg_197.
DR   KEGG; bas:BUsg197; -.
DR   HOGENOM; Q8K9U1; -.
DR   OMA; Q8K9U1; DICTEIW.
DR   BioCyc; BAPH198804:BUSG197-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004140; F:dephospho-CoA kinase activity; IEA:HAMAP.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00376; -; 1.
DR   InterPro; IPR001977; Depp_CoAkinase.
DR   PANTHER; PTHR10695; Depp_CoAkinase; 1.
DR   Pfam; PF01121; CoaE; 1.
DR   ProDom; PD003329; Depp_CoAkinase; 1.
DR   TIGRFAMs; TIGR00152; Depp_CoAkinase; 1.
DR   PROSITE; PS51219; DPCK; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coenzyme A biosynthesis; Complete proteome; Cytoplasm;
KW   Kinase; Nucleotide-binding; Transferase.
FT   CHAIN         1    210       Dephospho-CoA kinase.
FT                                /FTId=PRO_0000172920.
FT   DOMAIN        4    201       DPCK.
FT   NP_BIND       9     16       ATP (Potential).
SQ   SEQUENCE   210 AA;  24892 MW;  13B5614106473FCD CRC64;
     MIYIVALTGG ICSGKTTVSD RFKKIGINVI DTDVIGRKII EKNKKISDSI KKKFGKKILN
     KDNSINRFLL RNCIFNEKKS RLWLENILHP EILKKSKKKI KLIQSTWCLW VVPLLFEKKI
     QKKANRILLI DTPIRIQIRR MIKRDKININ EAKKIISYQV RRKKRISLSD DIILNKNKNI
     EKLSLYIHYL NNFYIYLSKQ NNPKNMKKII
//