Reviewed, UniProtKB/Swiss-Prot Q8K9U1 (COAE_BUCAP)

Names and origin

Protein names

Recommended name:
    Dephospho-CoA kinase
    EC=2.7.1.24
Alternative name(s):
    Dephosphocoenzyme A kinase

Gene names

Name:	coaE
Ordered Locus Names:	BUsg_197

Organism

Buchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP]

Taxonomic identifier

98794 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	210 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A By similarity.
Catalytic activity	ATP + 3'-dephospho-CoA = ADP + CoA. HAMAP MF_00376
Pathway	Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme A from pantothenate: step 5/5. HAMAP MF_00376
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the coaE family. Contains 1 DPCK (dephospho-CoA kinase) domain.

Ontologies

Keywords
Biological process	Coenzyme A biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP dephospho-CoA kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 210	210	Dephospho-CoA kinase HAMAP MF_00376		PRO_0000172920
Regions
	Domain	4 – 201	198	DPCK
	Nucleotide binding	9 – 16	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8K9U1-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 13B5614106473FCD	FASTA	210	24,892
	10 20 30 40 50 60 MIYIVALTGG ICSGKTTVSD RFKKIGINVI DTDVIGRKII EKNKKISDSI KKKFGKKILN 70 80 90 100 110 120 KDNSINRFLL RNCIFNEKKS RLWLENILHP EILKKSKKKI KLIQSTWCLW VVPLLFEKKI 130 140 150 160 170 180 QKKANRILLI DTPIRIQIRR MIKRDKININ EAKKIISYQV RRKKRISLSD DIILNKNKNI 190 200 210 EKLSLYIHYL NNFYIYLSKQ NNPKNMKKII

References

[1]

"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE013218 Genomic DNA. Translation: AAM67761.1.
RefSeq	NP_660550.1.
3D structure databases
HSSP	HSSP built from PDB template 1N3B based on UniProtKB P36679.
ModBase	Search...
Genome annotation databases
GeneID	1005394.
GenomeReviews	Gene locus BUsg_197 in contig AE013218_GR.
KEGG	bas:BUsg197.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8K9U1.
OMA	Q8K9U1. DICTEIW.
Enzyme and pathway databases
BioCyc	BAPH198804:BUSG197-MON.
Family and domain databases
HAMAP	MF_00376. [Tree]
InterPro	IPR001977. Depp_CoAkinase. [Graphical view]
PANTHER	PTHR10695. Depp_CoAkinase. 1 hit.
Pfam	PF01121. CoaE. 1 hit. [Graphical view]
ProDom	PD003329. Depp_CoAkinase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00152. Depp_CoAkinase. 1 hit.
PROSITE	PS51219. DPCK. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

COAE_BUCAP

Accession

Primary (citable) accession number: Q8K9U1

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
Last sequence update:	October 1, 2002
Last modified:	June 16, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)