Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q8K9U1 (COAE_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Dephospho-CoA kinase

EC=2.7.1.24
Alternative name(s):
Dephosphocoenzyme A kinase
Gene names
Name:coaE
Ordered Locus Names:BUsg_197
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length210 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A By similarity. HAMAP-Rule MF_00376

Catalytic activity

ATP + 3'-dephospho-CoA = ADP + CoA. HAMAP-Rule MF_00376

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5. HAMAP-Rule MF_00376

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00376.

Sequence similarities

Belongs to the CoaE family.

Contains 1 DPCK (dephospho-CoA kinase) domain.

Ontologies

Keywords
   Biological processCoenzyme A biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcoenzyme A biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

dephospho-CoA kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 210210Dephospho-CoA kinase HAMAP-Rule MF_00376
PRO_0000172920

Regions

Domain4 – 201198DPCK
Nucleotide binding9 – 168ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q8K9U1 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 13B5614106473FCD

FASTA21024,892
        10         20         30         40         50         60 
MIYIVALTGG ICSGKTTVSD RFKKIGINVI DTDVIGRKII EKNKKISDSI KKKFGKKILN 

        70         80         90        100        110        120 
KDNSINRFLL RNCIFNEKKS RLWLENILHP EILKKSKKKI KLIQSTWCLW VVPLLFEKKI 

       130        140        150        160        170        180 
QKKANRILLI DTPIRIQIRR MIKRDKININ EAKKIISYQV RRKKRISLSD DIILNKNKNI 

       190        200        210 
EKLSLYIHYL NNFYIYLSKQ NNPKNMKKII 

« Hide

References

[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE013218 Genomic DNA. Translation: AAM67761.1.
RefSeqNP_660550.1. NC_004061.1.

3D structure databases

ProteinModelPortalQ8K9U1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING198804.BUsg197.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM67761; AAM67761; BUsg_197.
GeneID1005394.
KEGGbas:BUsg197.
PATRIC21247181. VBIBucAph100086_0204.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0237.
KOK00859.
OMAGGKKRYP.
OrthoDBEOG6HTP3H.
ProtClustDBCLSK315784.

Enzyme and pathway databases

BioCycBAPH198804:GHMG-207-MONOMER.
UniPathwayUPA00241; UER00356.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00376. Dephospho_CoA_kinase.
InterProIPR001977. Depp_CoAkinase.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF01121. CoaE. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00152. TIGR00152. 1 hit.
PROSITEPS51219. DPCK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOAE_BUCAP
AccessionPrimary (citable) accession number: Q8K9U1
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: April 16, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names