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Reviewed, UniProtKB/Swiss-Prot Q8K9U1 (COAE_BUCAP)

Last modified June 16, 2009. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Dephospho-CoA kinase
    EC=2.7.1.24
Alternative name(s):
    Dephosphocoenzyme A kinase
Gene names
Name: coaE
Ordered Locus Names: BUsg_197
OrganismBuchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP]
Taxonomic identifier98794 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length210 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A By similarity.

Catalytic activity

ATP + 3'-dephospho-CoA = ADP + CoA. HAMAP MF_00376

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme A from pantothenate: step 5/5. HAMAP MF_00376

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the coaE family.

Contains 1 DPCK (dephospho-CoA kinase) domain.

Ontologies

Keywords
   Biological processCoenzyme A biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcoenzyme A biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

dephospho-CoA kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 210210Dephospho-CoA kinase HAMAP MF_00376
PRO_0000172920

Regions

Domain4 – 201198DPCK
Nucleotide binding9 – 168ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q8K9U1-1 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 13B5614106473FCD

FASTA21024,892
        10         20         30         40         50         60 
MIYIVALTGG ICSGKTTVSD RFKKIGINVI DTDVIGRKII EKNKKISDSI KKKFGKKILN 

        70         80         90        100        110        120 
KDNSINRFLL RNCIFNEKKS RLWLENILHP EILKKSKKKI KLIQSTWCLW VVPLLFEKKI 

       130        140        150        160        170        180 
QKKANRILLI DTPIRIQIRR MIKRDKININ EAKKIISYQV RRKKRISLSD DIILNKNKNI 

       190        200        210 
EKLSLYIHYL NNFYIYLSKQ NNPKNMKKII 

« Hide

References

[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

AE013218 Genomic DNA. Translation: AAM67761.1.
RefSeqNP_660550.1.

3D structure databases

HSSPHSSP built from PDB template 1N3B based on UniProtKB P36679.
ModBaseSearch...

Genome annotation databases

GeneID1005394.
GenomeReviewsGene locus BUsg_197 in contig AE013218_GR.
KEGGbas:BUsg197.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ8K9U1.
OMAQ8K9U1. DICTEIW.

Enzyme and pathway databases

BioCycBAPH198804:BUSG197-MON.

Family and domain databases

HAMAPMF_00376.
[Tree]
InterProIPR001977. Depp_CoAkinase.
[Graphical view]
PANTHERPTHR10695. Depp_CoAkinase. 1 hit.
PfamPF01121. CoaE. 1 hit.
[Graphical view]
ProDomPD003329. Depp_CoAkinase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR00152. Depp_CoAkinase. 1 hit.
PROSITEPS51219. DPCK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOAE_BUCAP
AccessionPrimary (citable) accession number: Q8K9U1
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: June 16, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents