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Q8K9T4

- MURG_BUCAP

UniProt

Q8K9T4 - MURG_BUCAP

Protein

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Gene

murG

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (01 Oct 2002)
      Previous versions | rss
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    Functioni

    Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).UniRule annotation

    Catalytic activityi

    UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. carbohydrate binding Source: InterPro
    2. UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity Source: UniProtKB-EC
    3. undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. cell cycle Source: UniProtKB-KW
    2. cell division Source: UniProtKB-KW
    3. lipid glycosylation Source: UniProtKB-HAMAP
    4. peptidoglycan biosynthetic process Source: UniProtKB-HAMAP
    5. regulation of cell shape Source: UniProtKB-KW
    6. UDP-N-acetylgalactosamine biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Cell cycle, Cell division, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

    Enzyme and pathway databases

    BioCyciBAPH198804:GHMG-220-MONOMER.
    UniPathwayiUPA00219.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseUniRule annotation (EC:2.4.1.227UniRule annotation)
    Alternative name(s):
    Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferaseUniRule annotation
    Gene namesi
    Name:murGUniRule annotation
    Ordered Locus Names:BUsg_210
    OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
    Taxonomic identifieri198804 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000000416: Chromosome

    Subcellular locationi

    Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

    GO - Cellular componenti

    1. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 354354UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferasePRO_0000109154Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi198804.BUsg210.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8K9T4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 28 family. MurG subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0707.
    KOiK02563.
    OMAiPFIKDMA.
    OrthoDBiEOG61VZFD.

    Family and domain databases

    HAMAPiMF_00033. MurG.
    InterProiIPR006009. GlcNAc_MurG.
    IPR004276. Glyco_trans_28.
    IPR007235. Glyco_trans_28_C.
    [Graphical view]
    PfamiPF04101. Glyco_tran_28_C. 1 hit.
    PF03033. Glyco_transf_28. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01133. murG. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8K9T4-1 [UniParc]FASTAAdd to Basket

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    MNSKRIIILA GGSGGHVFPG LTIAKHLIKK GWDINWIGTK NKIESEIIPK    50
    CNIKIHFIKI QGLRNSSLKN LIMTPINVLN SYLQVRKIIK NWIPDIILGM 100
    GGYVSGPGGL AAWSCKIPFI LHEQNKIAGI TNKLLSKIST KNMQAFSGTL 150
    LNAEIVGNPI RKNIIDIPPP IKRFKNRKGP LRILIIGGSQ GASIFNKILP 200
    KISFFLQEKA IIWHQSGNND LQKTRKKYKK YSTYKHIVSS FIKNIAEAYE 250
    WADIIISRSG ALTVSEITVV GLGAIFIPYP HKDKQQYLNA EDLENNGAAK 300
    IIEQSMFTAE LIIKILNSLN REKLFIMAKK AYSLGIRNST SKISKIIHDV 350
    SNKI 354
    Length:354
    Mass (Da):39,559
    Last modified:October 1, 2002 - v1
    Checksum:i848B5F42605F2852
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67773.1.
    RefSeqiNP_660562.1. NC_004061.1.

    Genome annotation databases

    EnsemblBacteriaiAAM67773; AAM67773; BUsg_210.
    GeneIDi1005409.
    KEGGibas:BUsg210.
    PATRICi21247209. VBIBucAph100086_0218.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013218 Genomic DNA. Translation: AAM67773.1 .
    RefSeqi NP_660562.1. NC_004061.1.

    3D structure databases

    ProteinModelPortali Q8K9T4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 198804.BUsg210.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM67773 ; AAM67773 ; BUsg_210 .
    GeneIDi 1005409.
    KEGGi bas:BUsg210.
    PATRICi 21247209. VBIBucAph100086_0218.

    Phylogenomic databases

    eggNOGi COG0707.
    KOi K02563.
    OMAi PFIKDMA.
    OrthoDBi EOG61VZFD.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .
    BioCyci BAPH198804:GHMG-220-MONOMER.

    Family and domain databases

    HAMAPi MF_00033. MurG.
    InterProi IPR006009. GlcNAc_MurG.
    IPR004276. Glyco_trans_28.
    IPR007235. Glyco_trans_28_C.
    [Graphical view ]
    Pfami PF04101. Glyco_tran_28_C. 1 hit.
    PF03033. Glyco_transf_28. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01133. murG. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Sg.

    Entry informationi

    Entry nameiMURG_BUCAP
    AccessioniPrimary (citable) accession number: Q8K9T4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2002
    Last sequence update: October 1, 2002
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Buchnera aphidicola (subsp. Schizaphis graminum)
      Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3