Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q8K9T4 (MURG_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
EC=2.4.1.227
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase
Gene names
Name:murG
Ordered Locus Names:BUsg_210
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera ›

Protein attributes

Sequence length354 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II) By similarity. HAMAP-Rule MF_00033

Catalytic activity

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP-Rule MF_00033

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00033

Subcellular location

Cell membrane; Peripheral membrane protein By similarity HAMAP-Rule MF_00033.

Sequence similarities

Belongs to the glycosyltransferase 28 family. MurG subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 354354UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase HAMAP-Rule MF_00033
PRO_0000109154

Sequences

Sequence LengthMass (Da)Tools
Q8K9T4 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 848B5F42605F2852

FASTA35439,559
        10         20         30         40         50         60 
MNSKRIIILA GGSGGHVFPG LTIAKHLIKK GWDINWIGTK NKIESEIIPK CNIKIHFIKI 

        70         80         90        100        110        120 
QGLRNSSLKN LIMTPINVLN SYLQVRKIIK NWIPDIILGM GGYVSGPGGL AAWSCKIPFI 

       130        140        150        160        170        180 
LHEQNKIAGI TNKLLSKIST KNMQAFSGTL LNAEIVGNPI RKNIIDIPPP IKRFKNRKGP 

       190        200        210        220        230        240 
LRILIIGGSQ GASIFNKILP KISFFLQEKA IIWHQSGNND LQKTRKKYKK YSTYKHIVSS 

       250        260        270        280        290        300 
FIKNIAEAYE WADIIISRSG ALTVSEITVV GLGAIFIPYP HKDKQQYLNA EDLENNGAAK 

       310        320        330        340        350 
IIEQSMFTAE LIIKILNSLN REKLFIMAKK AYSLGIRNST SKISKIIHDV SNKI

« Hide

References

[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE013218 Genomic DNA. Translation: AAM67773.1.
RefSeqNP_660562.1. NC_004061.1.

3D structure databases

ProteinModelPortalQ8K9T4.
ModBaseSearch...

Protein-protein interaction databases

STRING198804.BUsg210.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM67773; AAM67773; BUsg_210.
GeneID1005409.
KEGGbas:BUsg210.
PATRIC21247209. VBIBucAph100086_0218.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0707.
KOK02563.
OMADDHQTKN.
ProtClustDBPRK00726.

Enzyme and pathway databases

BioCycBAPH198804:GHMG-275-MONOMER.
UniPathwayUPA00219.

Family and domain databases

HAMAPMF_00033. MurG.
InterProIPR006009. GlcNAc_MurG.
IPR004276. Glyco_trans_28.
IPR007235. Glyco_trans_28_C.
[Graphical view]
PANTHERPTHR21015:SF22. PTHR21015:SF22. 1 hit.
PfamPF04101. Glyco_tran_28_C. 1 hit.
PF03033. Glyco_transf_28. 1 hit.
[Graphical view]
TIGRFAMsTIGR01133. murG. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMURG_BUCAP
AccessionPrimary (citable) accession number: Q8K9T4
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2002
Last modified: May 1, 2013
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents