Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8K9R4

- TADA_BUCAP

UniProt

Q8K9R4 - TADA_BUCAP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

tRNA-specific adenosine deaminase

Gene

tadA

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).UniRule annotation

Catalytic activityi

Adenine(34) in tRNA + H2O = hypoxanthine(34) in tRNA + NH3.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi55 – 551Zinc; via pros nitrogen; catalyticUniRule annotation
Active sitei57 – 571Proton donorUniRule annotation
Metal bindingi85 – 851Zinc; catalyticUniRule annotation
Metal bindingi88 – 881Zinc; catalyticUniRule annotation

GO - Molecular functioni

  1. tRNA-specific adenosine-34 deaminase activity Source: UniProtKB-HAMAP
  2. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. tRNA wobble adenosine to inosine editing Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-260-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA-specific adenosine deaminaseUniRule annotation (EC:3.5.4.33UniRule annotation)
Gene namesi
Name:tadAUniRule annotation
Ordered Locus Names:BUsg_246
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 151151tRNA-specific adenosine deaminasePRO_0000171730Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi198804.BUsg246.

Structurei

3D structure databases

ProteinModelPortaliQ8K9R4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 10399CMP/dCMP deaminase zinc-bindingUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the cytidine and deoxycytidylate deaminase family.UniRule annotation
Contains 1 CMP/dCMP deaminase zinc-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0590.
KOiK11991.
OMAiAVVFDSN.
OrthoDBiEOG64FKGZ.

Family and domain databases

HAMAPiMF_00972. tRNA_aden_deaminase.
InterProiIPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR016193. Cytidine_deaminase-like.
IPR028883. tRNA_aden_deaminase.
[Graphical view]
PfamiPF00383. dCMP_cyt_deam_1. 1 hit.
[Graphical view]
SUPFAMiSSF53927. SSF53927. 1 hit.
PROSITEiPS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8K9R4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKSNRDSYWM KIALKYAYYA EENGEVPIGA ILVFQEKIIG TGWNSVISQN
60 70 80 90 100
DSTAHAEIIA LREAGRNIKN YRLVNTTLYV TLQPCMMCCG AIINSRIKRL
110 120 130 140 150
VFGASYKDLK KNPFLKKIFI NLEKNKLKIK KHIMRNECAK ILSNFFKNKR

F
Length:151
Mass (Da):17,502
Last modified:October 1, 2002 - v1
Checksum:i8B3F699B11203951
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA. Translation: AAM67805.1.
RefSeqiNP_660594.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM67805; AAM67805; BUsg_246.
GeneIDi1005448.
KEGGibas:BUsg246.
PATRICi21247295. VBIBucAph100086_0257.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA. Translation: AAM67805.1 .
RefSeqi NP_660594.1. NC_004061.1.

3D structure databases

ProteinModelPortali Q8K9R4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198804.BUsg246.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM67805 ; AAM67805 ; BUsg_246 .
GeneIDi 1005448.
KEGGi bas:BUsg246.
PATRICi 21247295. VBIBucAph100086_0257.

Phylogenomic databases

eggNOGi COG0590.
KOi K11991.
OMAi AVVFDSN.
OrthoDBi EOG64FKGZ.

Enzyme and pathway databases

BioCyci BAPH198804:GHMG-260-MONOMER.

Family and domain databases

HAMAPi MF_00972. tRNA_aden_deaminase.
InterProi IPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR016193. Cytidine_deaminase-like.
IPR028883. tRNA_aden_deaminase.
[Graphical view ]
Pfami PF00383. dCMP_cyt_deam_1. 1 hit.
[Graphical view ]
SUPFAMi SSF53927. SSF53927. 1 hit.
PROSITEi PS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiTADA_BUCAP
AccessioniPrimary (citable) accession number: Q8K9R4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: October 1, 2002
Last modified: November 26, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3