SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8K9R4

- TADA_BUCAP

UniProt

Q8K9R4 - TADA_BUCAP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

tRNA-specific adenosine deaminase

Gene
tadA, BUsg_246
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) By similarity.UniRule annotation

Catalytic activityi

Adenine(34) in tRNA + H2O = hypoxanthine(34) in tRNA + NH3.UniRule annotation

Cofactori

Binds 1 zinc ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi55 – 551Zinc; via pros nitrogen; catalytic By similarity
Active sitei57 – 571Proton donor By similarity
Metal bindingi85 – 851Zinc; catalytic By similarity
Metal bindingi88 – 881Zinc; catalytic By similarity

GO - Molecular functioni

  1. tRNA-specific adenosine-34 deaminase activity Source: UniProtKB-HAMAP
  2. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. tRNA wobble adenosine to inosine editing Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-260-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA-specific adenosine deaminase (EC:3.5.4.33)
Gene namesi
Name:tadA
Ordered Locus Names:BUsg_246
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 151151tRNA-specific adenosine deaminaseUniRule annotationPRO_0000171730Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi198804.BUsg246.

Structurei

3D structure databases

ProteinModelPortaliQ8K9R4.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 10399CMP/dCMP deaminase zinc-bindingAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0590.
KOiK11991.
OMAiAVVFDSN.
OrthoDBiEOG64FKGZ.

Family and domain databases

HAMAPiMF_00972. tRNA_aden_deaminase.
InterProiIPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR016193. Cytidine_deaminase-like.
IPR028883. tRNA_aden_deaminase.
[Graphical view]
PfamiPF00383. dCMP_cyt_deam_1. 1 hit.
[Graphical view]
SUPFAMiSSF53927. SSF53927. 1 hit.
PROSITEiPS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8K9R4-1 [UniParc]FASTAAdd to Basket

« Hide

MKSNRDSYWM KIALKYAYYA EENGEVPIGA ILVFQEKIIG TGWNSVISQN    50
DSTAHAEIIA LREAGRNIKN YRLVNTTLYV TLQPCMMCCG AIINSRIKRL 100
VFGASYKDLK KNPFLKKIFI NLEKNKLKIK KHIMRNECAK ILSNFFKNKR 150
F 151
Length:151
Mass (Da):17,502
Last modified:October 1, 2002 - v1
Checksum:i8B3F699B11203951
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE013218 Genomic DNA. Translation: AAM67805.1.
RefSeqiNP_660594.1. NC_004061.1.
WP_011053772.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM67805; AAM67805; BUsg_246.
GeneIDi1005448.
KEGGibas:BUsg246.
PATRICi21247295. VBIBucAph100086_0257.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE013218 Genomic DNA. Translation: AAM67805.1 .
RefSeqi NP_660594.1. NC_004061.1.
WP_011053772.1. NC_004061.1.

3D structure databases

ProteinModelPortali Q8K9R4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198804.BUsg246.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM67805 ; AAM67805 ; BUsg_246 .
GeneIDi 1005448.
KEGGi bas:BUsg246.
PATRICi 21247295. VBIBucAph100086_0257.

Phylogenomic databases

eggNOGi COG0590.
KOi K11991.
OMAi AVVFDSN.
OrthoDBi EOG64FKGZ.

Enzyme and pathway databases

BioCyci BAPH198804:GHMG-260-MONOMER.

Family and domain databases

HAMAPi MF_00972. tRNA_aden_deaminase.
InterProi IPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR016193. Cytidine_deaminase-like.
IPR028883. tRNA_aden_deaminase.
[Graphical view ]
Pfami PF00383. dCMP_cyt_deam_1. 1 hit.
[Graphical view ]
SUPFAMi SSF53927. SSF53927. 1 hit.
PROSITEi PS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiTADA_BUCAP
AccessioniPrimary (citable) accession number: Q8K9R4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: October 1, 2002
Last modified: September 3, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi