ID   FABI_BUCAP              Reviewed;         260 AA.
AC   Q8K9Q6;
DT   15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   16-JUN-2009, entry version 48.
DE   RecName: Full=Enoyl-[acyl-carrier-protein] reductase [NADH];
DE            EC=1.3.1.9;
DE   AltName: Full=NADH-dependent enoyl-ACP reductase;
GN   Name=fabI; OrderedLocusNames=BUsg_255;
OS   Buchnera aphidicola subsp. Schizaphis graminum.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Buchnera.
OX   NCBI_TaxID=98794;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   MEDLINE=22084549; PubMed=12089438; DOI=10.1126/science.1071278;
RA   Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S.,
RA   Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
RT   "50 million years of genomic stasis in endosymbiotic bacteria.";
RL   Science 296:2376-2379(2002).
CC   -!- CATALYTIC ACTIVITY: Acyl-[acyl-carrier-protein] + NAD(+) = trans-
CC       2,3-dehydroacyl-[acyl-carrier-protein] + NADH.
CC   -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases
CC       (SDR) family. FabI subfamily.
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DR   EMBL; AE013218; AAM67813.1; -; Genomic_DNA.
DR   RefSeq; NP_660602.1; -.
DR   HSSP; P29132; 1DFI.
DR   GeneID; 1005457; -.
DR   GenomeReviews; AE013218_GR; BUsg_255.
DR   KEGG; bas:BUsg255; -.
DR   HOGENOM; Q8K9Q6; -.
DR   OMA; Q8K9Q6; LVHCLAF.
DR   BioCyc; BAPH198804:BUSG255-MON; -.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0004318; F:enoyl-[acyl-carrier-protein] reductase (NAD...; IEA:EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR002198; DH_sc/Rdtase_SDR.
DR   InterPro; IPR014358; Enoyl-ACP_Rdtase_NADH.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR19410; ADH_short_C2; 1.
DR   PANTHER; PTHR19410:SF12; Enoyl-ACP_rdct; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Fatty acid biosynthesis; Lipid synthesis; NAD;
KW   Oxidoreductase.
FT   CHAIN         1    260       Enoyl-[acyl-carrier-protein] reductase
FT                                [NADH].
FT                                /FTId=PRO_0000054897.
FT   NP_BIND      10     36       NAD (By similarity).
FT   ACT_SITE    156    156       Proton acceptor (By similarity).
SQ   SEQUENCE   260 AA;  29268 MW;  B97D1279FEFD3C71 CRC64;
     MGILKGKKIL ITGILNEKSI AFGIAKSMYK QEAELIFVCQ NKKIINKIKY LIKSINYNTI
     FFCDVSHDEN IKELFFNIKK VWNNFDGLVH SIAYCPKKQM HEDFVESSSR KSFNICHEIS
     SYSFLSMARE CKNMLNKFSS LVTLSYLGSQ KIVSNYNMMG LAKSSLEANV RYMANSLGKN
     NIRVNAISSG PIKTTSSYQI KNFNKIQKIH KLFSLTKNHV SSEEIGNVAA FLCSDLSIGI
     TGSIINVDHG FNLNGINSII
//