Reviewed, UniProtKB/Swiss-Prot Q8K9N9 (6PGL_BUCAP)

Names and origin

Protein names

Recommended name:
    6-phosphogluconolactonase
      Short name=6-P-gluconolactonase
    EC=3.1.1.31

Gene names

Name:	pgl
Ordered Locus Names:	BUsg_282

Organism

Buchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP]

Taxonomic identifier

98794 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	333 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity. HAMAP MF_01605
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605
Sequence similarities	Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 333	333	6-phosphogluconolactonase HAMAP MF_01605		PRO_0000171129

Sequences

	Sequence		Length	Mass (Da)
	Q8K9N9-1 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 7D6B61FAEC29855C	FASTA	333	38,373
	10 20 30 40 50 60 MQQIIYIANA ESENIEVWIL YNNGDMKLIQ TVQTDGQVQP ISIIKNTKLL YAGIRPKNRV 70 80 90 100 110 120 ITYQIDKNGL LKKKKESIVP GTPNYISFDS SEKFLFCSSY HADCISVSPL DKNGIPKDPI 130 140 150 160 170 180 QIIHNIEGCH AAKFNSKYNV LFITSLKNDC IYLYYLTHFG ILKSTEQKLV FSQKNSGPRH 190 200 210 220 230 240 VIFHPNQNFS YTVNELNGSV DVWKISKENK VLEVKNIQNI KLLNDLISKK YWSSDIHLTS 250 260 270 280 290 300 CGNFLYVSDR YLNSISLFHV NKNDNTIIFF KQYLTEEQPR AFCIDRNNNY LIVIGQKSNK 310 320 330 LSVYKICQKT GELKKINQYQ TGNGPLWITS FLI

References

[1]

"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE013218 Genomic DNA. Translation: AAM67839.1.
RefSeq	NP_660628.1.
3D structure databases
SMR	Q8K9N9. Positions 1-331.
ModBase	Search...
Genome annotation databases
GeneID	1005486.
GenomeReviews	Gene locus BUsg_282 in contig AE013218_GR.
KEGG	bas:BUsg282.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG741123.
OMA	AYVINEL.
Enzyme and pathway databases
BioCyc	BAPH198804:BUSG282-MONOMER.
Family and domain databases
HAMAP	MF_01605. 6P-gluconolactonase. [Tree]
InterPro	IPR015943. WD40/YVTN_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

6PGL_BUCAP

Accession

Primary (citable) accession number: Q8K9N9

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 15, 2002
Last sequence update:	October 1, 2002
Last modified:	February 9, 2010
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)