Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.UniRule annotation

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.UniRule annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Glucose-6-phosphate 1-dehydrogenase (zwf)
  2. 6-phosphogluconolactonase (pgl)
  3. 6-phosphogluconate dehydrogenase, decarboxylating (gnd)
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processCarbohydrate metabolism, Glucose metabolism

Enzyme and pathway databases

BioCyciBAPH198804:G1FZU-300-MONOMER
UniPathwayiUPA00115; UER00409

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonaseUniRule annotation (EC:3.1.1.31UniRule annotation)
Short name:
6-P-gluconolactonaseUniRule annotation
Gene namesi
Name:pglUniRule annotation
Ordered Locus Names:BUsg_282
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera
Proteomesi
  • UP000000416 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001711291 – 3336-phosphogluconolactonaseAdd BLAST333

Interactioni

Protein-protein interaction databases

STRINGi198804.BUsg282

Structurei

3D structure databases

ProteinModelPortaliQ8K9N9
SMRiQ8K9N9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cycloisomerase 2 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105HHQ Bacteria
COG2706 LUCA
KOiK07404
OMAiEGNWPRD
OrthoDBiPOG091H07R3

Family and domain databases

Gene3Di2.130.10.10, 1 hit
HAMAPiMF_01605 6P_gluconolactonase, 1 hit
InterProiView protein in InterPro
IPR022528 6-phosphogluconolactonase_YbhE
IPR019405 Lactonase_7-beta_prop
IPR015943 WD40/YVTN_repeat-like_dom_sf
PfamiView protein in Pfam
PF10282 Lactonase, 1 hit

Sequencei

Sequence statusi: Complete.

Q8K9N9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQIIYIANA ESENIEVWIL YNNGDMKLIQ TVQTDGQVQP ISIIKNTKLL
60 70 80 90 100
YAGIRPKNRV ITYQIDKNGL LKKKKESIVP GTPNYISFDS SEKFLFCSSY
110 120 130 140 150
HADCISVSPL DKNGIPKDPI QIIHNIEGCH AAKFNSKYNV LFITSLKNDC
160 170 180 190 200
IYLYYLTHFG ILKSTEQKLV FSQKNSGPRH VIFHPNQNFS YTVNELNGSV
210 220 230 240 250
DVWKISKENK VLEVKNIQNI KLLNDLISKK YWSSDIHLTS CGNFLYVSDR
260 270 280 290 300
YLNSISLFHV NKNDNTIIFF KQYLTEEQPR AFCIDRNNNY LIVIGQKSNK
310 320 330
LSVYKICQKT GELKKINQYQ TGNGPLWITS FLI
Length:333
Mass (Da):38,373
Last modified:October 1, 2002 - v1
Checksum:i7D6B61FAEC29855C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA Translation: AAM67839.1
RefSeqiWP_011053806.1, NC_004061.1

Genome annotation databases

EnsemblBacteriaiAAM67839; AAM67839; BUsg_282
KEGGibas:BUsg_282

Similar proteinsi

Entry informationi

Entry namei6PGL_BUCAP
AccessioniPrimary (citable) accession number: Q8K9N9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: October 1, 2002
Last modified: March 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health