Q8K9N8 (LOLC_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Lipoprotein-releasing system transmembrane protein LolC

Gene names

Name:	lolC
Ordered Locus Names:	BUsg_284

Organism

Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]

Taxonomic identifier

198804 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Schizaphis graminum)

Protein attributes

Sequence length	399 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA By similarity.
Subcellular location	Cell membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 399	399	Lipoprotein-releasing system transmembrane protein LolC		PRO_0000201809
Regions
	Transmembrane	25 – 45	21	Helical; Potential
	Transmembrane	266 – 286	21	Helical; Potential
	Transmembrane	312 – 332	21	Helical; Potential
	Transmembrane	358 – 378	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8K9N8 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: BF4B1BD037EE9BB0	FASTA	399	46,486
	10 20 30 40 50 60 MYKPIYIFIG LRYLWNPYLP NFKKIIIILS ILGIGIGISS TIITISIMNG FQNKFKNDIL 70 80 90 100 110 120 SFIPHIIITN KNRNINKLNF PKETLKLKNV EEITDFISKK VIIENKNEIN IGEIIGINIK 130 140 150 160 170 180 NEKNLENYNI KKFLHTLHSR KYNAIIGSEL AKKMHVNIND QIKLIVLPIS KKKFLQNDLN 190 200 210 220 230 240 IKLFKITGIF STNSEIDEYQ ILINKKNALN FLNYNKNYIT GWKIKLKDPF ILNIQKIKKL 250 260 270 280 290 300 NKNFIILDWK TKKGELFKAM KIEKYIMLFF FILILLVSSF NIVISLTMNV LDKKNNISIF 310 320 330 340 350 360 QSQGLSRYKI MLIFIILGST ISIVGNSFGT IISIILIFQK DFLNFLIKIF FIDIEIPIEI 370 380 390 SLIQILTINI TFIFLTILST LYPIWYAIKS TPSRILSDE

References

[1]

"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sg.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE013218 Genomic DNA. Translation: AAM67840.1.
RefSeq	NP_660629.1. NC_004061.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	198804.BUsg284.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAM67840; AAM67840; BUsg_284.
GeneID	1005488.
KEGG	bas:BUsg284.
PATRIC	21247375. VBIBucAph100086_0297.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG4591.
KO	K09808.
OMA	FYAHSEV.
ProtClustDB	CLSK315866.
Enzyme and pathway databases
BioCyc	BAPH198804:GHMG-298-MONOMER.
Family and domain databases
InterPro	IPR025857. MacB_PCD. IPR003838. Permease_FtsX-like. [Graphical view]
Pfam	PF02687. FtsX. 1 hit. PF12704. MacB_PCD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LOLC_BUCAP

Accession

Primary (citable) accession number: Q8K9N8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
Last sequence update:	October 1, 2002
Last modified:	May 29, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program