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Q8K9L9 (TSAB_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaB
Gene names
Name:tsaB
Ordered Locus Names:BUsg_315
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length210 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t6A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the KAE1 / TsaD family. TsaB subfamily.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processthreonylcarbamoyladenosine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 210210tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
PRO_0000096993

Sequences

Sequence LengthMass (Da)Tools
Q8K9L9 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: CC92F0C8113A8342

FASTA21024,122
        10         20         30         40         50         60 
MSDIILAIDT SIDHCSVAVY KKKVIYSLSE NCKKEHTIKI LPMIKKVLMN AKITLKDLNY 

        70         80         90        100        110        120 
VAFSKGPGKF TGIRISIGIA QSLSLSLKIP IFGISTLSIL AQKAWRKYKK KQILVAVNAK 

       130        140        150        160        170        180 
IGQVYWGEYL RNNTLLWTGE KTESLIKINK IEDKMKKLKK KWILVGDGWK KIKRENSLKF 

       190        200        210 
EQKKILYPNA KDIIPFLFSE NSKPRILSFF 

« Hide

References

[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE013218 Genomic DNA. Translation: AAM67869.1.
RefSeqNP_660658.1. NC_004061.1.

3D structure databases

ProteinModelPortalQ8K9L9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING198804.BUsg315.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM67869; AAM67869; BUsg_315.
GeneID1005520.
KEGGbas:BUsg315.
PATRIC21247439. VBIBucAph100086_0329.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1214.
KOK14742.
OMAFIGVRIG.
OrthoDBEOG6D8B8B.

Enzyme and pathway databases

BioCycBAPH198804:GHMG-329-MONOMER.

Family and domain databases

InterProIPR000905. Gcp-like_dom.
IPR022496. T6A_YeaZ.
[Graphical view]
PfamPF00814. Peptidase_M22. 1 hit.
[Graphical view]
TIGRFAMsTIGR03725. T6A_YeaZ. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTSAB_BUCAP
AccessionPrimary (citable) accession number: Q8K9L9
Entry history
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: October 1, 2002
Last modified: May 14, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names