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Protein

tRNA threonylcarbamoyladenosine biosynthesis protein TsaB

Gene

tsaB

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t6A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-329-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaB
Gene namesi
Name:tsaB
Ordered Locus Names:BUsg_315
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 210210tRNA threonylcarbamoyladenosine biosynthesis protein TsaBPRO_0000096993Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi198804.BUsg315.

Structurei

3D structure databases

ProteinModelPortaliQ8K9L9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the KAE1 / TsaD family. TsaB subfamily.Curated

Phylogenomic databases

eggNOGiCOG1214.
KOiK14742.
OMAiFIGVRIG.
OrthoDBiEOG6D8B8B.

Family and domain databases

InterProiIPR000905. Gcp-like_dom.
IPR022496. T6A_YeaZ.
[Graphical view]
PfamiPF00814. Peptidase_M22. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03725. T6A_YeaZ. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8K9L9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDIILAIDT SIDHCSVAVY KKKVIYSLSE NCKKEHTIKI LPMIKKVLMN
60 70 80 90 100
AKITLKDLNY VAFSKGPGKF TGIRISIGIA QSLSLSLKIP IFGISTLSIL
110 120 130 140 150
AQKAWRKYKK KQILVAVNAK IGQVYWGEYL RNNTLLWTGE KTESLIKINK
160 170 180 190 200
IEDKMKKLKK KWILVGDGWK KIKRENSLKF EQKKILYPNA KDIIPFLFSE
210
NSKPRILSFF
Length:210
Mass (Da):24,122
Last modified:October 1, 2002 - v1
Checksum:iCC92F0C8113A8342
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA. Translation: AAM67869.1.
RefSeqiNP_660658.1. NC_004061.1.
WP_011053836.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM67869; AAM67869; BUsg_315.
KEGGibas:BUsg315.
PATRICi21247439. VBIBucAph100086_0329.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA. Translation: AAM67869.1.
RefSeqiNP_660658.1. NC_004061.1.
WP_011053836.1. NC_004061.1.

3D structure databases

ProteinModelPortaliQ8K9L9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198804.BUsg315.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM67869; AAM67869; BUsg_315.
KEGGibas:BUsg315.
PATRICi21247439. VBIBucAph100086_0329.

Phylogenomic databases

eggNOGiCOG1214.
KOiK14742.
OMAiFIGVRIG.
OrthoDBiEOG6D8B8B.

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-329-MONOMER.

Family and domain databases

InterProiIPR000905. Gcp-like_dom.
IPR022496. T6A_YeaZ.
[Graphical view]
PfamiPF00814. Peptidase_M22. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03725. T6A_YeaZ. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiTSAB_BUCAP
AccessioniPrimary (citable) accession number: Q8K9L9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: October 1, 2002
Last modified: May 27, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.