Reviewed, UniProtKB/Swiss-Prot Q8K9L5 (RSMC_BUCAP)

Names and origin

Protein names

Recommended name:
    Ribosomal RNA small subunit methyltransferase C
    EC=2.1.1.52
Alternative name(s):
    rRNA (guanine-N(2)-)-methyltransferase rsmC
    16S rRNA m2G1207 methyltransferase

Gene names

Name:	rsmC
Ordered Locus Names:	BUsg_319

Organism

Buchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP]

Taxonomic identifier

98794 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	336 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle By similarity.
Catalytic activity	S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N(2)-methylguanine. HAMAP MF_01862
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the methyltransferase superfamily. RsmC family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rRNA methylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 336	336	Ribosomal RNA small subunit methyltransferase C HAMAP MF_01862		PRO_0000097488

Sequences

	Sequence		Length	Mass (Da)
	Q8K9L5-1 [UniParc]. Last modified November 15, 2002. Version 2. Checksum: 43BBC5E1D2535CFF	FASTA	336	38,871
	10 20 30 40 50 60 MIFSKNSQLI LRHQKIFKNK IVFFSGNIED ELPINLLTIK TKIHLQKSQN FLKINNNKNI 70 80 90 100 110 120 TFYRKLLVSQ DTVQDCNILI YYWPKNKSEA RFQLFNILSF LPIKSEIFIV GSNSSGVKSA 130 140 150 160 170 180 KLILEESIKL KKIDNANHSI LMSGILINKT KFKLEKFFKI HIWKNLIIKS LPGVFGHKKI 190 200 210 220 230 240 DEGSKFIAST FSEKINGKIL DVGCGSGFLS VSILRKSPKC VVTMIDRKLS ALESSKATLD 250 260 270 280 290 300 ANFFKGEVLS SNIYSNIFKK FNMIVSNPPL HDDLKINFDI TKKIIFNSKK HLKKNGELRF 310 320 330 VTNHCFSYDF YLKKVFSEFH IMKKDNKYKV YQAFLK

References

[1]

"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE013218 Genomic DNA. Translation: AAM67873.1. Different initiation.
RefSeq	NP_660662.2.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1005524.
GenomeReviews	Gene locus BUsg_319 in contig AE013218_GR.
KEGG	bas:BUsg319.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8K9L5.
OMA	Q8K9L5. IGENRAG.
Enzyme and pathway databases
BioCyc	BAPH198804:BUSG319-MON.
Family and domain databases
HAMAP	MF_01862. [Tree]
InterPro	IPR013675. Mtase_sm_N. IPR007848. Small_mtfrase. [Graphical view]
Pfam	PF05175. MTS. 1 hit. PF08468. MTS_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RSMC_BUCAP

Accession

Primary (citable) accession number: Q8K9L5

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 15, 2002
Last sequence update:	November 15, 2002
Last modified:	June 16, 2009
This is version 45 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)