Q8K9L4 (OMPA_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
OmpA-like protein

Gene names

Name:	ompA
Ordered Locus Names:	BUsg_320

Organism

Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]

Taxonomic identifier

198804 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Schizaphis graminum)

Protein attributes

Sequence length	347 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Acts as a porin with low permeability that allows slow penetration of small solutes By similarity.
Subunit structure	Monomer Probable.
Subcellular location	Cell membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the OmpA family. Contains 1 OmpA-like domain.

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Cell membrane Membrane
Domain	Signal Transmembrane Transmembrane beta strand
Molecular function	Porin
PTM	Disulfide bond
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ion transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cell outer membrane Inferred from electronic annotation. Source: InterPro plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell pore complex Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	porin activity Inferred from electronic annotation. Source: UniProtKB-KW structural molecule activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21	Potential
	Chain	22 – 347	326	OmpA-like protein		PRO_0000020106
Regions
	Transmembrane	26 – 39	14	Beta stranded; Potential
	Transmembrane	63 – 75	13	Beta stranded; Potential
	Transmembrane	78 – 93	16	Beta stranded; Potential
	Transmembrane	106 – 116	11	Beta stranded; Potential
	Transmembrane	120 – 135	16	Beta stranded; Potential
	Transmembrane	154 – 165	12	Beta stranded; Potential
	Transmembrane	171 – 187	17	Beta stranded; Potential
	Transmembrane	193 – 204	12	Beta stranded; Potential
	Domain	220 – 347	128	OmpA-like
	Region	207 – 218	12	Hinge-like
Amino acid modifications
	Disulfide bond	321 ↔ 333		By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8K9L4 [UniParc]. Last modified October 1, 2002. Version 1. Checksum: 55D23E2AF7D5A887	FASTA	347	39,950
	10 20 30 40 50 60 MKKQALTIIF LLVSLVTGIQ AKENDHWYLG TKMGWSDFNI LEYRSKDITP FDTKIDTKNP 70 80 90 100 110 120 LGAPVFGLFL GYEFNPYFSF EIENDTTGFS PHLIFQKNEQ NIQINSLQLA TKLSYPITDD 130 140 150 160 170 180 FHIYTQLGGM MFWDNLSFKK DLQNIFTEKS RLIPNVSLGA EYIFNKKFIT RLDYTWKSNI 190 200 210 220 230 240 AKIMNLSMKP VLGDVALSFG WKFGKSNINE IFSSYIPQSS DKQYVALNEN INFPFNSTEL 250 260 270 280 290 300 KPISHDKLQK LQKEIKNIKS KNIFIMLSGH ADRIGNKEYN QKLSENRAYS IKNYFTSHGI 310 320 330 340 SQDKISIQGM GNEFSLTNQI CKDVSDRPLL ISCLAPDRRV EIEVLSD

References

[1]

"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sg.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE013218 Genomic DNA. Translation: AAM67874.1.
RefSeq	NP_660663.1. NC_004061.1.
3D structure databases
ProteinModelPortal	Q8K9L4.
ModBase	Search...
Protein-protein interaction databases
STRING	198804.BUsg320.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAM67874; AAM67874; BUsg_320.
GeneID	1005525.
KEGG	bas:BUsg320.
PATRIC	21247455. VBIBucAph100086_0334.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2885.
KO	K03286.
OMA	RVEYQYL.
ProtClustDB	CLSK315890.
Enzyme and pathway databases
BioCyc	BAPH198804:GHMG-337-MONOMER.
Family and domain databases
Gene3D	2.40.160.20. 1 hit. 3.30.1330.60. 1 hit.
InterPro	IPR011250. OMP/PagP_b-brl. IPR006664. OMP_bac. IPR002368. OmpA. IPR006690. OMPA-like_CS. IPR000498. OmpA-like_TM_dom. IPR006665. OmpA/MotB_C. [Graphical view]
Pfam	PF00691. OmpA. 1 hit. PF01389. OmpA_membrane. 1 hit. [Graphical view]
PRINTS	PR01021. OMPADOMAIN. PR01022. OUTRMMBRANEA.
SUPFAM	SSF103088. OmpA/MotB_C. 1 hit. SSF56925. SSF56925. 1 hit.
PROSITE	PS01068. OMPA_1. 1 hit. PS51123. OMPA_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

OMPA_BUCAP

Accession

Primary (citable) accession number: Q8K9L4

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 15, 2002
Last sequence update:	October 1, 2002
Last modified:	May 29, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program