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Q8K9J6 (FABD_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Malonyl CoA-acyl carrier protein transacylase
Short name=MCT
EC=2.3.1.39
Gene names
Name:fabD
Ordered Locus Names:BUsg_338
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length310 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Malonyl-CoA + [acyl-carrier-protein] = CoA + malonyl-[acyl-carrier-protein].

Pathway

Lipid metabolism; fatty acid biosynthesis.

Sequence similarities

Belongs to the fabD family.

Ontologies

Keywords
   Biological processFatty acid biosynthesis
Lipid synthesis
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processfatty acid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular function[acyl-carrier-protein] S-malonyltransferase activity

Inferred from electronic annotation. Source: EC

binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 310310Malonyl CoA-acyl carrier protein transacylase
PRO_0000194212

Sites

Active site931 By similarity
Active site2011 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8K9J6 [UniParc].

Last modified October 1, 2002. Version 1.
Checksum: 376559CB2CD16F85

FASTA31035,351
        10         20         30         40         50         60 
MNSFAMLFPG QGSQYKNMLS SFFQKKNNLF KKIFDEASEY VNYNLLNLIK NGAKKKRDDY 

        70         80         90        100        110        120 
KYIQSAILTS SIAIYQLWKE KNGRRPALMS GHSLGEYSAL VCANAIKFSD ALKIVKLRSK 

       130        140        150        160        170        180 
LMQKIIINKP SLVQAIIGLD KVIIKNICLQ YLPKIVSIAS INSDDQIIIS GEKLAVREVG 

       190        200        210        220        230        240 
LKCKKKGAKY VIKLNINTPI HSQLMKPVSE QIKYLLKSIK IKSPQIPVIN NVDVICEKNE 

       250        260        270        280        290        300 
KKIKKALVRQ FYSTVRWKEI IDLIKSKKIF TMLEIGPNKI LSNLIKKNDN ITVLNTNNLK 

       310 
NFLIAFKTIH

« Hide

References

[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE013218 Genomic DNA. Translation: AAM67892.1.
RefSeqNP_660681.1. NC_004061.1.

3D structure databases

ProteinModelPortalQ8K9J6.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBUCT00000000246; EBBUCP00000000246; EBBUCG00000000246.
GeneID1005568.
GenomeReviewsGene locus BUsg_338 in contig AE013218_GR.
KEGGbas:BUsg338.
PATRIC21247491. VBIBucAph100086_0352.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000008204.
HOGENOMHBG687898.
OMAFAANYNC.

Enzyme and pathway databases

BioCycBAPH198804:BUSG338-MONOMER.

Family and domain databases

InterProIPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view]
Gene3DG3DSA:3.40.366.10. Ac_transferase_reg. 2 hits.
KOK00645.
PfamPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
PIRSFPIRSF000446. Mct. 1 hit.
SUPFAMSSF52151. Acyl_Trfase/lysoPlipase. 1 hit.
SSF55048. Malonyl_transacylase_ACP-bd. 1 hit.
TIGRFAMsTIGR00128. FabD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameFABD_BUCAP
AccessionPrimary (citable) accession number: Q8K9J6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: October 1, 2002
Last modified: January 25, 2012
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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