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Q8K9J6

- FABD_BUCAP

UniProt

Q8K9J6 - FABD_BUCAP

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Protein
Malonyl CoA-acyl carrier protein transacylase
Gene
fabD, BUsg_338
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier-protein].

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei93 – 931 By similarity
Active sitei201 – 2011 By similarity

GO - Molecular functioni

  1. [acyl-carrier-protein] S-malonyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. fatty acid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-355-MONOMER.
UniPathwayiUPA00094.

Names & Taxonomyi

Protein namesi
Recommended name:
Malonyl CoA-acyl carrier protein transacylase (EC:2.3.1.39)
Short name:
MCT
Gene namesi
Name:fabD
Ordered Locus Names:BUsg_338
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 310310Malonyl CoA-acyl carrier protein transacylase
PRO_0000194212Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi198804.BUsg338.

Structurei

3D structure databases

ProteinModelPortaliQ8K9J6.

Family & Domainsi

Sequence similaritiesi

Belongs to the FabD family.

Phylogenomic databases

eggNOGiCOG0331.
KOiK00645.
OMAiIWRVWQE.
OrthoDBiEOG6W19KW.

Family and domain databases

Gene3Di3.40.366.10. 2 hits.
InterProiIPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view]
PfamiPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000446. Mct. 1 hit.
SUPFAMiSSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
TIGRFAMsiTIGR00128. fabD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8K9J6-1 [UniParc]FASTAAdd to Basket

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MNSFAMLFPG QGSQYKNMLS SFFQKKNNLF KKIFDEASEY VNYNLLNLIK    50
NGAKKKRDDY KYIQSAILTS SIAIYQLWKE KNGRRPALMS GHSLGEYSAL 100
VCANAIKFSD ALKIVKLRSK LMQKIIINKP SLVQAIIGLD KVIIKNICLQ 150
YLPKIVSIAS INSDDQIIIS GEKLAVREVG LKCKKKGAKY VIKLNINTPI 200
HSQLMKPVSE QIKYLLKSIK IKSPQIPVIN NVDVICEKNE KKIKKALVRQ 250
FYSTVRWKEI IDLIKSKKIF TMLEIGPNKI LSNLIKKNDN ITVLNTNNLK 300
NFLIAFKTIH 310
Length:310
Mass (Da):35,351
Last modified:October 1, 2002 - v1
Checksum:i376559CB2CD16F85
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE013218 Genomic DNA. Translation: AAM67892.1.
RefSeqiNP_660681.1. NC_004061.1.
WP_011053859.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM67892; AAM67892; BUsg_338.
GeneIDi1005568.
KEGGibas:BUsg338.
PATRICi21247491. VBIBucAph100086_0352.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE013218 Genomic DNA. Translation: AAM67892.1 .
RefSeqi NP_660681.1. NC_004061.1.
WP_011053859.1. NC_004061.1.

3D structure databases

ProteinModelPortali Q8K9J6.
ModBasei Search...

Protein-protein interaction databases

STRINGi 198804.BUsg338.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM67892 ; AAM67892 ; BUsg_338 .
GeneIDi 1005568.
KEGGi bas:BUsg338.
PATRICi 21247491. VBIBucAph100086_0352.

Phylogenomic databases

eggNOGi COG0331.
KOi K00645.
OMAi IWRVWQE.
OrthoDBi EOG6W19KW.

Enzyme and pathway databases

UniPathwayi UPA00094 .
BioCyci BAPH198804:GHMG-355-MONOMER.

Family and domain databases

Gene3Di 3.40.366.10. 2 hits.
InterProi IPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view ]
Pfami PF00698. Acyl_transf_1. 1 hit.
[Graphical view ]
PIRSFi PIRSF000446. Mct. 1 hit.
SUPFAMi SSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
TIGRFAMsi TIGR00128. fabD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiFABD_BUCAP
AccessioniPrimary (citable) accession number: Q8K9J6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: October 1, 2002
Last modified: September 3, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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