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Protein

Malonyl CoA-acyl carrier protein transacylase

Gene

fabD

Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier-protein].

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei93 – 931By similarity
Active sitei201 – 2011By similarity

GO - Molecular functioni

  1. [acyl-carrier-protein] S-malonyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. fatty acid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-355-MONOMER.
UniPathwayiUPA00094.

Names & Taxonomyi

Protein namesi
Recommended name:
Malonyl CoA-acyl carrier protein transacylase (EC:2.3.1.39)
Short name:
MCT
Gene namesi
Name:fabD
Ordered Locus Names:BUsg_338
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 310310Malonyl CoA-acyl carrier protein transacylasePRO_0000194212Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi198804.BUsg338.

Structurei

3D structure databases

ProteinModelPortaliQ8K9J6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FabD family.Curated

Phylogenomic databases

eggNOGiCOG0331.
KOiK00645.
OMAiRRIDKTV.
OrthoDBiEOG6W19KW.

Family and domain databases

Gene3Di3.40.366.10. 2 hits.
InterProiIPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view]
PfamiPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000446. Mct. 1 hit.
SUPFAMiSSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
TIGRFAMsiTIGR00128. fabD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8K9J6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSFAMLFPG QGSQYKNMLS SFFQKKNNLF KKIFDEASEY VNYNLLNLIK
60 70 80 90 100
NGAKKKRDDY KYIQSAILTS SIAIYQLWKE KNGRRPALMS GHSLGEYSAL
110 120 130 140 150
VCANAIKFSD ALKIVKLRSK LMQKIIINKP SLVQAIIGLD KVIIKNICLQ
160 170 180 190 200
YLPKIVSIAS INSDDQIIIS GEKLAVREVG LKCKKKGAKY VIKLNINTPI
210 220 230 240 250
HSQLMKPVSE QIKYLLKSIK IKSPQIPVIN NVDVICEKNE KKIKKALVRQ
260 270 280 290 300
FYSTVRWKEI IDLIKSKKIF TMLEIGPNKI LSNLIKKNDN ITVLNTNNLK
310
NFLIAFKTIH
Length:310
Mass (Da):35,351
Last modified:October 1, 2002 - v1
Checksum:i376559CB2CD16F85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA. Translation: AAM67892.1.
RefSeqiNP_660681.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM67892; AAM67892; BUsg_338.
GeneIDi1005568.
KEGGibas:BUsg338.
PATRICi21247491. VBIBucAph100086_0352.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013218 Genomic DNA. Translation: AAM67892.1.
RefSeqiNP_660681.1. NC_004061.1.

3D structure databases

ProteinModelPortaliQ8K9J6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198804.BUsg338.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM67892; AAM67892; BUsg_338.
GeneIDi1005568.
KEGGibas:BUsg338.
PATRICi21247491. VBIBucAph100086_0352.

Phylogenomic databases

eggNOGiCOG0331.
KOiK00645.
OMAiRRIDKTV.
OrthoDBiEOG6W19KW.

Enzyme and pathway databases

UniPathwayiUPA00094.
BioCyciBAPH198804:GHMG-355-MONOMER.

Family and domain databases

Gene3Di3.40.366.10. 2 hits.
InterProiIPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view]
PfamiPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000446. Mct. 1 hit.
SUPFAMiSSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
TIGRFAMsiTIGR00128. fabD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiFABD_BUCAP
AccessioniPrimary (citable) accession number: Q8K9J6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: October 1, 2002
Last modified: March 4, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.